Clinical trials: Herniation, Disc
Lumbar Disc Herniation, Instrument-assisted Soft Tissue Mobilization
The Efficacy Of Instrument-Assisted Soft Tissue Mobilization At Lumbar Region Disc Herniations
This study was carried out to investigate the effect of instrument-assisted soft tissue mobilization in patients with lomber region disc herniation.
- Trial name
- NCT04334122
- Testing
- Instrument-assisted soft tisue mobilization, Traditional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Low Level Laser Therapy
Combined Effect of Low Level Laser Therapy and Neural Mobilization on Lumber Disc Prolapse
This study attempts to answer the following research question: what is the combined effect of low level laser therapy and neural mobilization on lumber disc prolapse in decreasing pain, improving functional disability, improving…
- Trial name
- LLLT-NM-LDP (NCT07138300)
- Testing
- Low Level Laser Therapy by (Eme Physio, Lasermed 2200), GaAs laser, 1 cm2 beam area,7,000 Hz, 17 mW, 1 J/cm2, Pesaro, Italy), neural mobilization
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pain, Back, Spinal Stenosis
PREventing Pain After Surgery
The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use.
- Conditions
- Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis
- Trial name
- PREPS (NCT05306665)
- Testing
- ACT intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Brigham and Women's Hospital
Lumbar Disc Herniation
Elongation Longitudinaux Avec Decoaption Osteo-Articulaire (ELDOA) in Lumbar Disc Protrusion
The aim of this randomized controlled trial will be to determine the effectiveness of ELDOA for treating lumbar disc protrusion.
- Trial name
- NCT04043611
- Testing
- Conservative physical therapy management, ELDOA
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- Riphah International University
Lumbar Disc Herniation
Efficacy of Navigable Percutaneous Plasma Disc Decompression Device (L'DISQ) in Patients With Severe Lumbar Disc Herniation
This study aims to assess the clinical outcome of percutaneous disc decompression using the L'DISQ in patients with severe lumbar disc herniation (LDH).
- Trial name
- L'DISQ (NCT05231759)
- Testing
- L'DISQ
- Volunteers
- 30 people
- Sponsor
- Korea University Anam Hospital
Surgical Wound Infection
Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery
The purpose of the study is to determine whether a single, pre-operative dose of cefuroxime is effective in preventing surgical site infection in patients undergoing surgery for herniated disk
- Trial name
- NCT00530400
- Testing
- cefuroxime
- Where
- 2 sites in Switzerland
- Volunteers
- 1,369 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Intervertebral Disk Displacement, Disk Prolapse
Analgetic and Anxiolytic Effect of Preoperative Pregabalin
The purpose of this study is to determine whether the use of oral pregabalin 150 mg as premedication reduces the amount and degree of postoperative pain.
- Trial name
- NCT00353704
- Testing
- pregabalin, morphine
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Asker & Baerum Hospital
Lumbar Disc Herniation
Short Versus Long Post-Operative Restrictions Following Lumbar Discectomy
Post-operative restrictions following lumbar discectomy is a controversial topic. While the most widely accepted protocol restricts bending, lifting, and twisting for four to six weeks following discectomy, a number of studies…
- Trial name
- NCT01363830
- Testing
- Two-Week Post-Operative Restriction, Six-Week Post-Operative Restriction
- Where
- 3 sites in United States
- Volunteers
- 420 people
- Sponsor
- Brigham and Women's Hospital
Protruded Disk
CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients
The purpose of the study is to evaluate the efficacy of CLARIX™ 100 and CLARIX™ CORD 1K as a tissue barrier when used as an annular patch in discectomy patients with low back \& leg pain when compared to traditional discectomy…
- Trial name
- NCT03113786
- Testing
- CLARIX™100, CLARIX CORD 1K
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Amniox Medical, Inc.
Necrosis of Femoral Head, Knee Osteoarthritis
Probiotics Attenuate Postoperative Cognition Decline
The aim of this study was to evaluate whether perioperative probiotics can reduce the incidence of postoperative cognitive dysfunction and postoperative delirium.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Neck of Femur, Lumbar Disc Herniation
- Trial name
- NCT04017403
- Testing
- Bifidobacterium triple live capsule
- Where
- 3 sites in China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Cervical Foraminal Stenosis, Cervical Disc Herniation
Safety and Efficacy of Electromagnetic Navigation System Assisted Percutaneous Endoscopic Lumbar Decompression
There is a shallow learning curve with TELD (transforaminal endoscopic lumbar discectomy). The aim of this study is to assess the safety and efficacy of TELD assisted by electromagnetic navigation for treating lumbar disc…
- Trial name
- NCT05270486
- Testing
- Electromagnetic navigation system
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Disc Herniation
Comparison of the Effectiveness of Reformer Pilates and Conventional Physiotherapy in Lumbar Disc Herniation
This study aims to examine the effects of Reformer Pilates on patient-reported outcomes such as pain level, fatigue, sleep quality, anxiety, kinesiophobia, and quality of life in individuals with lumbar disc herniation (LDH) and…
- Trial name
- NCT06846892
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yasemin Şahbaz
Pain, Neck
Clinical Effects of Ozone Therapy in Cervical Disc Hernia
The aim of the study is to evaluate the clinical effects of Ozone-oxygen therapy as therapeutic substance for nucleolysis application in the patients with cervical disc hernia who had chronic pain and weakness on the neck…
- Trial name
- NCT03056911
- Testing
- Ozone
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Sakarya University
Lumbar Disc Herniation
Exploring the Distribution Patterns and Infrared Characteristics of Force-sensitive Acupoints in Different Lumbar Nerve Segments in Patients With LDH Based on "Press Quickly" Theory
Utilizing the "responsive acupoint palpation" technique and infrared thermography, we investigated the distribution patterns of pressure-sensitive acupoints across different lumbar spinal segments in patients with lumbar disc…
- Trial name
- NCT06318156
- Testing
- Infrared thermal imaging
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zhou Xingchen
Lumbar Disc Herniation, Low Back Pain
Comparison Of Early Mobilization And Electrical Stimulation On Functional Recovery After Lumbar Disc Herniation Surgery
This randomized controlled trial aims to compare the effectiveness of early mobilization alone versus early mobilization combined with electrical stimulation on functional recovery following lumbar disc herniation surgery.
- Conditions
- Lumbar Disc Herniation, Low Back Pain, Postoperative Rehabilitation
- Trial name
- EMES-LDH (NCT07575477)
- Testing
- Early Mobilization Program, Electrical Stimulation (NMES/TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Sciatica, Radiculopathy
The Value of Traction in Treatment of Lumbar Radiculopathy
The purpose of this study is to determine the effectiveness of adding mechanical traction to standard physical therapy treatments for patients with low back pain.
- Conditions
- Sciatica, Radiculopathy, Spinal Diseases, Musculoskeletal Diseases
- Trial name
- NCT00942227
- Testing
- Physical therapy rehabilitation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Intermountain Health Care, Inc.
Disk Herniated Lumbar, Physiotherapy
Supervised Physical Therapy Versus Unsupervised Home Exercise After Surgery for Lumbar Disc Herniation
This is a randomized controlled trial evaluation effect of postoperative rehabilitation after surgery for lumbar disc herniation.
- Conditions
- Disk Herniated Lumbar, Physiotherapy, Surgery
- Trial name
- NCT03505918
- Testing
- No referral for rehabilitation
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Spine Centre of Southern Denmark
Lumbar Disc Herniation, Multimodal Brain Function
Brain Effect Mechanism of Lever Positioning Manipulation on LDH Analgesia Based on Multimodal MRI
In order to further investigate the key brain targets and central response mechanism characteristics of analgesia, the dominant disease of LDH was taken as the object of this study, which was divided into operation group, comfort…
- Conditions
- Lumbar Disc Herniation, Multimodal Brain Function, Analgesia Mechanism, Lever Positioning Manipulation
- Trial name
- NCT05613179
- Testing
- Group1 (lever positioning manipulation)
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Lumbar Disc Herniation
Paraspinal Muscle Remodeling
Lumbar disc herniation is the most common diagnosed degenerative pathology in the lumbar spine with a prevalence of 2 to 3% in the adult population.
- Trial name
- NCT03753711
- Testing
- Multifidus muscle biopsy during minimally invasive back surgery
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Lumbar Disc Herniation, Respiratory Mechanics
Pulmonary Mechanics and Cerebral Oxygenation During Prone Lumbar Disc Surgery
This prospective observational study aims to evaluate the relationship between changes in respiratory mechanics and cerebral oxygenation in adult patients undergoing elective lumbar disc surgery in the prone position under…
- Conditions
- Lumbar Disc Herniation, Respiratory Mechanics, Cerebral Oxygenation
- Trial name
- NCT07862257
- Testing
- Prone Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital