Clinical trials: Herniation, Disc
Lumbar Disc Herniation, Lumbar Degenerative Disease
Multivariate Analysis and Risk Factors Were Used to Predict the Short-term Postoperative Pain of Degenerative Lumbar Spine
The objective of this retrospective clinical study wasto study the risk factors for short-term low back and leg pain after PLIF in patients with lumbar Degenerative disease, and to establish a risk prediction model for short-term…
- Conditions
- Lumbar Disc Herniation, Lumbar Degenerative Disease, Sarcopenia
- Trial name
- NCT06628583
- Testing
- Magnetic Resonance Imaging with Contrast
- Where
- China
- Volunteers
- 936 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Lumbar and Other Intervertebral Disc Disorders With Radiculopathy
Epidural Clonidine for Lumbosacral Radiculopathy
This was a randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy.
- Trial name
- NCT00588354
- Testing
- Clonidine, Triamcinolone hexacetonide, Lidocaine HCl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Degenerative Disc Disease, Disc Herniation
Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
The purpose of this study is to evaluate the efficacy of SeaSpine Shoreline device in surgery of the cervical spine.
- Trial name
- NCT06415136
- Testing
- SeaSpine Shoreline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Source
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine Surgery
Intraoperative Neuromonitoring (IONM) is a tool used by neurophysiologists during spine surgery to prevent irreversible damage to the spinal cord during procedures through a system of alerts.
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Stenosis
- Trial name
- IONM (NCT05110833)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Allina Health System
Lumbar Disc Herniation, Sacroiliac Joint Dysfunction
The Prevalence Of Sacroiliac Joint Dysfunction In Patients With Lumbar Disc Hernia
In this study evaluated the prevalence of sacroiliac joint dysfunction in patients with lumbar disc hernia and examined the variations in clinical parameters cause by this combination.
- Trial name
- NCT03965507
- Testing
- Evaluation of the prevalence of sacroiliac joint dysfunction in lumbar disc herniation
- Volunteers
- 234 people
- Sponsor
- European University of Lefke
Cervical Disc Prolapse
Effect of Superficial Cervical Plexus Block on the Postoperative Quality of Recovery
Pain and discomfort after anterior cervical spine surgery is difficult to quantify and quoted as moderate in severity, often needing oral opioid analgesics.
- Trial name
- QoR (NCT01662219)
- Testing
- Superficial cervical plexus block for experimental group
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- University Health Network, Toronto
Postoperative Pain, Lumbar Disc Herniation
Comparison of Quadro Iliac vs Erector Spinae Plane Block on Postoperative Pain and Opioid Use in Lumbar Discectomies
This multicenter, randomized, controlled study aims to compare the analgesic efficacy of Quadro Iliac Plane Block (QIPB) and Erector Spinae Plane (ESP) Block in lumbar vertebra surgeries.
- Trial name
- NCT06656507
- Testing
- Quadro Iliac Plane Block (QIPB), Erector Spinae Plane Block (ESP)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Lumbar Spine Disc Herniation, Lumbar Radiculitis
Dexamethasone Versus Depo Medrol in Lumbar Epidurals
Comparison of Dexamethasone versus Depo Medrol when used in lumbar epidural injections will be conducted on subjects that have not had previous injections or have not had an injection in the last 12 months.
- Conditions
- Lumbar Spine Disc Herniation, Lumbar Radiculitis, Lumbar Back Pain
- Trial name
- NCT01397552
- Testing
- Dexamethasone, methylprednisolone acetate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
Herniated Disc
Radiofrequency Nucleoplasty vs Percutaneous Nucleotomy vs Decompression Catheter in Lumbar Disc Herniation
The purpose of this study is to learn which of three minimally invasive procedures is the most effective for treatment of contained lumbar disc herniation.
- Trial name
- NCT00300898
- Testing
- Nucleoplasty, Percutaneous decompression, Intervertebral electrothermal disc decompression (IDET)
- Sponsor
- The Cleveland Clinic
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Laminectomy, Postperative Pain Management
Dexamethasone as ESPB Adjuvant in Lumbar Laminectomy
Laminectomy is a routine procedure for patients with lumbar spinal stenosis, offering significant benefits such as reduced low back pain, alleviation of radiculopathy, and improved motor strength 1 23.
- Conditions
- Laminectomy, Postperative Pain Management, Prostaglandin E2, Lumbal Disc Herniation
- Trial name
- NCT07429708
- Testing
- Bilateral ESPB: Ropivacaine 0.375% + Dexamethasone 5mg, Bilateral ESPB: Ropivacaine 0.375%
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Udayana University
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Lumbar Disc Herniation
Bladder Meridian Gua Sha for Lumbar Disc Herniation: Efficacy and CRP Regulation Via Cutaneous-Meridian-Visceral Axis in Shen Period
Based on the "Cutaneous Region-Meridian-Visceral" axis theory, in this study, we investigated clinical efficacy of the Gua Sha intervention on the Bladder Meridian during the Shen Period (3:00-5:00 p.m.) for lumbar disc…
- Trial name
- CRP (NCT07754422)
- Testing
- Control group（standard treatment and care）, Observation group（standard treatment supplemented with Gua Sha）
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Intervertebral Disc Herniation, Back Pain
Immune Response During the Conservative and Minimal Invasive Treatment of Pain Caused by Lumbar Disc Herniation
Bulging of the intervertebral disc in the lumbar part of the spine is one of the most common degenerative changes of the spine in the elderly population, which causes various symptoms such as radicular pain.
- Conditions
- Intervertebral Disc Herniation, Back Pain, Analgesic Nephropathy, Inflammatory Response
- Trial name
- NCT06545812
- Testing
- Transforaminal epidural steroid injection, Physical therapy for disc herniation
- Where
- Croatia
- Volunteers
- 128 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Herniated Intervertebral Disc
Artificial Intelligence Assisted Spine Rehabilitation in Cervical Disc Herniation
The aim of this study is to investigate the effect of artificial intelligence-assisted spinal rehabilitation in neck hernia compared to traditional methods.
- Trial name
- NCT06632028
- Testing
- artificial intelligence assisted spinal rehabilitation, conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Okan University
Back Pain With Radiation, Radiculopathy
Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nuclectomy 3
This study is a First in Human, prospective, multi-center clinical study intended to collect safety and performance information for the Spinal Stabilization Technologies PerQdisc® Nucleus Replacement System and procedure…
- Conditions
- Back Pain With Radiation, Radiculopathy, Back Pain, Disc Herniation
- Trial name
- LOPAIN3 (NCT05732818)
- Testing
- PerQdisc Nucleus Replacement System
- Where
- 2 sites in Paraguay, Uzbekistan
- Volunteers
- 50 people
- Sponsor
- Spinal Stabilization Technologies
Degenerative Disc Disease, Spondylolisthesis
Clinical and Radiological Outcomes of Oblique Lateral Lumbar Interbody Fusion
This study is undertaken to evaluate the outcomes of Oblique Lateral Lumbar Interbody Fusion (OLLIF). Specifically, the study seeks to measure outcomes on radiological imaging, outcomes reported by the patients on standardized…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Lumbar Disc Herniation
- Trial name
- NCT03726190
- Testing
- Oblique Lateral Lumbar Fusion
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Tristate Brain and Spine Institute
Lumbar Radiculopathy, Lumbar Disc Herniation
Treatment Response to TFESI and DRG Pulsed RF in Lumbar Spinal Stenosis and Disc Herniation
Lumbar radiculopathy caused by conditions such as lumbar disc herniation (LDH) and lumbar spinal stenosis (LSS) can lead to chronic pain and reduced quality of life.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07509580
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University