Clinical trials: Herniorrhaphies
Hernia, Inguinal, Laparoscopic Surgery
Progrip Versus ProFlor: Two Fixation Free Devices for Laparoscopic Inguinal Hernia Repair
there are currently two methods for fixation free laparoscopic inguinal hernia repair specifically based on the intrinsic properties of the device used.
- Trial name
- ProPro (NCT06556498)
- Testing
- Proflor group, Progrip group
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Palermo
Hiatal Hernia, Paraesophageal Hernia
Nissen Versus Dor Hiatal Hernia Repair
Hiatal hernia can present with a wide range of symptoms. An usual surgical repair technique usually includes Nissen fundoplication, while other procedures are less frequently employed.
- Conditions
- Hiatal Hernia, Paraesophageal Hernia, Recurrence
- Trial name
- NiDor (NCT06725433)
- Testing
- Nissen fundoplication, Dor fundoplication
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- Kuopio University Hospital
Hernia, Ventral, Hernia Incisional
Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh
This study compares short term outcomes of patients undergoing a hernia repair with heavy weight mesh vs medium weight mesh in clean-contaminated and contaminated cases.
- Trial name
- NCT06409091
- Testing
- Medium weight or Heavy weight mesh
- Where
- United States
- Volunteers
- 1,496 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Inguinal Hernia Without Obstruction or Gangrene
Closed Suction Drain vs no Drain on Symptomatic Seroma Formation After Laparoscopic Inguinal Hernia Repair
The current study aims to determine whether a use of closed suction drain following laparoscopic inguinal hernia surgery performed for an inguinoscrotal variety can decrease the incidence of symptomatic seroma formation requiring…
- Trial name
- SALHS (NCT03563092)
- Testing
- Laparoscopic Inguinal Hernia (TEP/TAPP) Surgery
- Where
- India
- Volunteers
- 100 people
- Sponsor
- GEM Hospital & Research Center
Postsurgical Pain
Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
A Three-Part, Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Adaptive Safety, Pharmacokinetics, and Preliminary Efficacy Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
- Trial name
- NCT04774328
- Testing
- CA-008 (vocacapsaicin)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Concentric Analgesics
Recurrent Inguinal Hernia
Recurrent Inguinal Hernia Treatment - Lichtenstein Versus Laparoscopic Totally Extraperitoneal Preperitoneal Hernioplasty
The study aims at detecting possible differences between an open (Lichtenstein) and a video-assisted (TEP) technique in treating recurrent inguinal hernia.
- Trial name
- NCT00642200
- Testing
- Lichtenstein hernioplasty, Laparoscopic TEP
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- North Karelia Central Hospital
Inguinal Hernia, Postoperative Pain
Comparing Erector Spinae Plane (ESP) and Transversus Abdominis Plane (TAP) Block in Inguinal Hernia
The Erectore Spinae Plane Block (ESP Block) is a recently described technique for regional anesthesia that has shown promising results in the treatment of pain after thoracic surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Anesthesia, Local, Anesthesia Complication
- Trial name
- TAPESP (NCT04750512)
- Testing
- ESP block, TAP block
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ghielmini Enea
Chronic Pain
Sensory Abnormalities in Post-surgical Peripheral Neuropathy
The concept of normality is a cornerstone in medical practice and research. As an example, in clinical chemistry, a laboratory value based on a plasma sample exceeding the +/- 1.96 x standard deviation (SD) range, referenced from…
- Trial name
- NCT03966677
- Where
- Denmark
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hernia Repair, Hernia Inguinal
Postsurgical Analgesia After Hernia Repair
The study is designed to evaluate the safety, efficacy, and pharmacokinetics (PK) of three ascending doses of AMT-143 to determine the appropriate dose of AMT-143 for the management of postsurgical pain following inguinal hernia…
- Conditions
- Hernia Repair, Hernia Inguinal, Hernia Surgery, Hernia, Inguinal/Surgery
- Trial name
- NCT06709612
- Testing
- AMT-143, ropivacaine
- Sponsor
- AmacaThera Inc.
Hernia, Recurrence
Magnetic Resonance Imaging of Mesh Position After Ventral Hernia Repair
Purpose of the study is the visualization of the mesh and the determination of the mesh surface observed by MRI at 3 weeks and 13 months after ventral hernia repair with mesh visible IPOM (Dynamesh®).
- Trial name
- NCT02177214
- Testing
- MRI scan
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Incisional Hernia
Risk of Recurrence After Incisional Hernia Repair With Mesh Fixation With Absorbable Versus Non-absorbable Tacks
Laparoscopic incisional hernia repair a variety of fixation methods has been proposed to ensure the correct and stable intra-abdominal placement of the mesh, in order to prevent recurrence, but on the other hand avoiding…
- Trial name
- ABSTACK (NCT01740882)
- Where
- Denmark
- Volunteers
- 816 people
- Sponsor
- Hvidovre University Hospital
Hernia, Inguinal, Robotic Surgical Procedures
Robotic vs. Conventional Minimal-invasive Inguinal Hernia Repair
Minimal invasive techniques have become a well established approach for inguinal hernia repair over the last decade in developed countries.
- Trial name
- ROGER-RCT (NCT05216276)
- Testing
- TEP, rTAPP
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Basel, Switzerland
Inguinal Hernia
Safety and Performance Study of TIGR Matrix Surgical Mesh in Inguinal Hernia Repair
This an open, uncontrolled multicenter clinical study to assess the safety and performance of the WK-6 surgical mesh in adult patients with unilateral inguinal hernia.
- Trial name
- NCT01193985
- Testing
- TIGR Matrix Surgical Mesh
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Novus Scientific
Hernia, Inguinal
Absorbable Sutures , Non Absorbable Sutures or Biologic Fibrin Glue for Protesic Mesh Fixing in Lichtenstein Technique for Primitive Groin Hernia Repair: a Randomized Prospective Multicentric Trial
this study has the aim to analize the correlation between three different methods of mesh fixation ( using absorbable or non absorbable sutures or fibrin biological glue) and recurrance and chronic pain ,in the Lichtenstein…
- Trial name
- NCT02011698
- Testing
- Lichtenstein technique groin hernia repair with mesh. Use of absorbale sutures for mesh fixation, Lichtenstein technique groin hernia repair with mesh. Use of non absorbable sutures for mesh fixation, Lichtenstein technique groin hernia repair with mesh. Use of fibrin biological glue for mesh fixation
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Inguinal Hernia
The (Cost-) Effectiveness of Paediatric Laparoscopic Hernia Repair Compared to Open Hernia Repair
This study assess the (cost-)effectiveness of open versus laparoscopic Percutaneous Inguinal Ring Suturing (PIRS) technique for unilateral inguinal hernia repair in children aged 0-16 years.
- Trial name
- HERNIIA-2 (NCT06451432)
- Testing
- Percutaneous Inguinal Ring Suturing (PIRS) technique
- Where
- 9 sites in Netherlands
- Volunteers
- 464 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hernia, Inguinal, Hernia, Femoral
Chronic Postoperative Pain After the Lichtenstein Groin Hernioplasty
The study attempts to quantify the relative risks for chronic postoperative inguinal pain (CPIP) after Lichtenstein repair of groin hernia, depending on mesh type and fixation suture material.
- Conditions
- Hernia, Inguinal, Hernia, Femoral, Postoperative Pain, Chronic Pain
- Trial name
- NCT04839848
- Testing
- Lichtenstein mesh repair
- Volunteers
- 80,733 people
- Sponsor
- Karolinska Institutet
Ventral Hernia Repair, Abdominal Hernia
Comparison Between eTEP-RS vs IPOM PLUS
This study aims to compare the outcomes of Enhanced View Totally Extraperitoneal Rives-Stoppa (eTEP-RS) repair and Intraperitoneal Onlay Mesh Plus (IPOM Plus) repair in the management of ventral wall hernias.
- Trial name
- NCT07055464
- Testing
- eTEP-RS Hernia Repair, IPOM Plus Hernia Repair
- Where
- India
- Volunteers
- 174 people
- Sponsor
- GSVM Medical College
Parastomal Hernia
Improving Decisions and Outcomes in Parastomal Hernia Surgery
The goal of this observational study is to help improve decisions about planned surgery for parastomal hernia and understand the results of treatment.
- Trial name
- IDOPS (NCT07866339)
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Erling Oma
Inguinal Hernia
Pain and Quality of Life After Inguinal Hernia Repair
This study aims to explore the difference in outcomes relating to pain and quality of life after open, laparoscopic, and robotic-assisted inguinal hernia repair.
- Trial name
- PREPARE (NCT04074200)
- Testing
- Open Inguinal Hernia Repair, Laparoscopic Inguinal Hernia Repair, Robotic-Assisted Inguinal Hernia Repair
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Intuitive Surgical
Hernia, Ventral
Abdominal Wall Function and Quality of Life and Before and After Incisional Hernia Repair
The primary objective of the present study is to investigate a possible correlation between abdominal wall function and subjective measures of QoL before and after laparoscopic repair of small- to medium sized incisional hernia.
- Trial name
- QualiFunc (NCT02320071)
- Testing
- Examination of abdominal wall strength changes over time
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Bispebjerg Hospital