Clinical trials: Herpetic Neuralgia
Postherpetic Neuralgia ( PHN )
Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic Neuralgia
This randomized controlled clinical trial will evaluate and compare the efficacy and safety of intradermal injection of exosomes, platelet-rich plasma, and corticosteroid in patients with post-herpetic neuralgia.
- Trial name
- NCT07565844
- Testing
- Exosomes, PRP, Corticosteroids
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Zagazig University
Herpetic Neuralgia
Pregabalin Treatment and Prevention Post-herpetic Neuralgia
Pregabalin is effective on herpetic neuralgia, but whether can prevention post-herpetic neuralgia still need to confirm.
- Trial name
- NCT03186443
- Testing
- Pregabalin, Gabapentin
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Post Herpetic Neuralgia, Pain
A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.
This study is a 3-part, Double-blind, Randomized, Placebo-controlled, Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics/Pharmacodynamic properties of iN1011-N17 after Oral Administration in Healthy…
- Conditions
- Post Herpetic Neuralgia, Pain, Osteoarthritis, Neuropathic Pain
- Trial name
- NCT06218784
- Testing
- iN1011-N17 HCl Suspension (Part 1), iN1011-N17 HCl Capsule (Part 1), iN1011-N17 HCl Capsule (Part 2)
- Where
- Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- iN Therapeutics Co., Ltd.
Neuralgia, Postherpetic
A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN)
The purpose of this study is to determine whether gabapentin enacarbil (XP13512/GSK1838262), hereafter referred to as GEn is effective in the treatment of neuropathic pain associated with post-herpetic neuralgia (PHN).
- Trial name
- NCT00619476
- Testing
- GEn 1200mg/day, GEn 2400mg/day, GEn 3600mg/day
- Where
- 83 sites in United States, Canada
- Volunteers
- 376 people
- Sponsor
- XenoPort, Inc.
Trigeminal Nerve Injuries, Post-herpetic Neuralgia
Transcranial Magnetic Stimulation for Facial Pain
Complex oro-facial pain is a poorly diagnosed and poorly treated cause of significant suffering and disability. This study will explore the ability of fMRI to identify patients with complex oro-facial pain who respond to…
- Conditions
- Trigeminal Nerve Injuries, Post-herpetic Neuralgia, Facial Pain, Nervus Intermedius Neuralgia
- Trial name
- NCT02633306
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Minnesota
Neuralgia, Postherpetic
A Study Assessing Efficacy of Brivaracetam in Subjects With Persistent Pain After Shingles (Post-herpetic Neuralgia)
Study will assess efficacy, safety and tolerability of brivaracetam in post-herpetic neuralgia (PHN). Duration of 7 weeks divided into 3 periods with no up-titration, nor down-titration.
- Trial name
- NCT00160667
- Testing
- Brivaracetam
- Where
- 50 sites in Belgium, Bulgaria and 8 more
- Volunteers
- 152 people
- Sponsor
- UCB Pharma
Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy
Validation Study of Neuropathic Pain
This study seeks to validate clinically evoked or obtained objective pain signs with the patient's corresponding quantified subjective pain symptoms.
- Conditions
- Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy, Post Herpetic Pain
- Trial name
- NCT00623961
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Wisconsin, Madison
Postherpetic Neuralgia, Pain
Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia
Neuropathic pain is caused by a virus commonly associated with chicken pox. This virus may become dormant in the nervous system and later reactivate causing herpes zoster, also known as "shingles".
- Trial name
- NCT00478179
- Testing
- Transdermal/Patch (Bupivacaine TTS [Eladur™])
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Durect
Postherpetic Neuralgia
Evaluation of Civamide Patch in Treatment of Postherpetic Neuralgia and Post-Incisional Neuralgia
This proof of concept study is designed to evaluate the safety and efficacy of topically administered Civamide Patch for the treatment of moderate to severe daily pain associated with postherpetic neuralgia localized to the…
- Trial name
- NCT00845923
- Testing
- Civamide Patch
- Where
- 4 sites in United States, Canada
- Volunteers
- 22 people
- Sponsor
- Winston Laboratories
Non-diabetic Painful Peripheral Polyneuropathy, Postherpetic Neuralgia (PHN)
A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment
This study is comparing the efficacy and tolerability of Qutenza with that of pregabalin in patients suffering from peripheral neuropathic pain.
- Conditions
- Non-diabetic Painful Peripheral Polyneuropathy, Postherpetic Neuralgia (PHN), Peripheral Nerve Injury (PNI)
- Trial name
- ELEVATE (NCT01713426)
- Testing
- Qutenza, Pregabalin
- Where
- 98 sites in Armenia, Austria and 20 more
- Volunteers
- 568 people
- Sponsor
- Astellas Pharma Europe Ltd.
Herpes Zoster, Post-herpetic Neuralgia
Reduction of Postherpetic Neuralgia in Herpes Zoster
The addition of gabapentin therapy to standard antiviral treatment with valacyclovir in acute herpes zoster patients will decrease the incidence of post-herpetic neuralgia.
- Trial name
- NCT01250561
- Testing
- Gabapentin, Valacyclovir
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- Center for Clinical Studies, Texas
Post Herpetic Neuralgia (PHN)
Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic Neuralgia
The purpose of this study is to evaluate the therapeutic efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) in the treatment of patients with post-herpetic neuralgia (PHN).
- Trial name
- NCT07123987
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS), traditional medical treatment for PHN
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mohamed Hosny Ismail Easa
Herpetic Neuralgia
To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Herpetic Neuralgia
Investigate the efficacy and safety of HSK16149 capsules in Chinese herpetic Neuralgia following 4 weeks treatment in comparison to pregabalin.
- Trial name
- NCT05763550
- Testing
- HSK16149 20mg BID, HSK16149 40mg BID, Pregabalin 150mg
- Where
- China
- Volunteers
- 331 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Herpes Zoster, Herpes Zoster Vaccine
Study to Estimate the Burden of Herpes Zoster (HZ) and Post-herpetic Neuralgia (PHN) in Italy
The purpose of this study is to collect data on the incidence, complications, economic burden and impact on the quality of life in adults aged ≥ 50 years with HZ disease in Italy.
- Trial name
- NCT01772160
- Testing
- Data collection
- Where
- 43 sites in Italy
- Volunteers
- 395 people
- Sponsor
- GlaxoSmithKline
Post Herpetic Neuralgia
Eslicarbazepine Acetate as Therapy in Post-Herpetic Neuralgia
The primary objective of this study is to assess the efficacy of Eslicarbazepine acetate (ESL) as therapy in subjects with Post-herpetic Neuralgia (PHN) over a 15 week treatment phase.
- Trial name
- NCT01124097
- Testing
- Eslicarbazepine acetate (BIA 2-093)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- Bial - Portela C S.A.
Post Herpetic Neuralgia
Efficacy, Tolerability, and Safety of NXN-462 in Patients With Post-Herpetic Neuralgia
The purpose of this study is to investigate whether NXN-462, a selective nNOS inhibitor, is effective in reducing pain levels in patients with post-herpetic neuralgia.
- Trial name
- NCT01748877
- Testing
- NXN-462
- Where
- 25 sites in United States, Canada
- Volunteers
- 188 people
- Sponsor
- NeurAxon Inc.
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Herpes Zoster
Measuring Herpes Zoster and PHN Associated Burden of Illness and Health Care Utilization Costs in Thailand
Total 7 institutions will be recruited i.e. Clinical Infectious Disease Research Unit Department of Clinical Tropical Medicine, Faculty of Tropical Medicine Mahidol University,Bamrasnaradura Infectious Disease Institute…
- Trial name
- NCT00526864
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Mahidol University
Herpes Zoster, Neuralgia, Postherpetic
Subcutaneous Lidocaine Injection in Acute Herpes Zoster Neuralgia and Post-herpetic Neuralgia
In this study, it was aimed to compare the effect of subcutaneous lidocaine injection, which is routinely applied in pain clinic,in patients who present with pain complaints due to acute herpes zoster and post-herpetic neuralgia…
- Trial name
- SCL-HZ/PHN (NCT06882525)
- Testing
- Lidocaine (drug)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara City Hospital Bilkent
Post Herpetic Neuralgia
Acupuncture as Treatment of Post-herpetic Neuralgia: A RCT A Double-blinded Randomized Clinical Trial.
The aim of this study is to perform the first RCT investigating the possible effect of superficial dry-needling (SDN) - a special kind of acupuncture used for PHN. The participants will be divided into two groups.
- Trial name
- NCT03974438
- Testing
- Superficial dry needling / Acupunture
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital