Clinical trials: Hidden Hearing Loss
Hearing Loss
Validation and Evaluation of the French Version of a Hearing Loss Screening Questionnaire in Adults Aged 60 Years Old and More
Nowadays in France, there is no organized screening of the hearing loss in the elderly; however, it is a very common disease and simples tests to perform to detect it exist.
- Trial name
- VF DEPIST 60 (NCT04159428)
- Testing
- HHIE-S survey score
- Where
- France
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Surdity, the Audiological and Electrophysiological Profile of Hidden Hearing Loss
Diagnosis of Hidden Hearing Loss in Adults : Refining the Audiological Profile for Better Diagnosis.
This study aims to investigate the underlying mechanisms of speech-in-noise difficulties in patients with normal conventional pure-tone and speech audiometry.
- Trial name
- SURDICACH (NCT07738549)
- Testing
- Audiometric tests
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Sensorineural Hearing Loss
Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
This is a randomized, double-blind study of PIPE-505, or placebo, in subjects with hearing loss associated with speech-in-noise impairment.
- Trial name
- NCT04462198
- Testing
- PIPE-505
- Where
- 8 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Contineum Therapeutics
Healthy Volunteer, Without Hearing Disorders
Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers
Acoustic overexposure can induced temporary or hearing loss. Usually hearing loss is associated with cochlear cell damages. Recently, a new pathological entity was described and called "hidden hearing loss".
- Trial name
- ECOG (NCT04198909)
- Testing
- Electrocochleography, electrophysiology thet for analyse the wave I generated by the auditory pathways
- Where
- France
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Auditory Diseases, Central
Comparing Hearing Aid Fitting Methods in Blast-exposed Veterans
Since 2000, at least 250,000 U.S. Service members have experienced a blast-related mild traumatic brain injury. A retrospective analysis of over 100,000 post-9/11 Veterans shows that blast injury more than doubles the risk of a…
- Trial name
- SBA (NCT06309264)
- Testing
- Phonak Lumina P90
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Seneorineural Deafness, Sudden Sensorineural Hearing Loss
A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients
The goal of this 2 step-up, exploratory study is to test safey, tolerability and PK/PD profiles in healthy volunteers and safety, tolerability and efficacy in sudden sensorineural hearing loss patients as an early salvage…
- Trial name
- NCT06249919
- Testing
- NS101
- Where
- 15 sites in South Korea
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Neuracle Science Co., LTD.
Hearing Loss, Sensorineural, Cochlear Synaptopathy
Evaluation of the CochSyn Test Prototype to Measure Cochlear Synaptopathy
This study investigates a newly developed test, The CochSyn test that can quantify cochlear synaptopathy (CS) (a new type of sensorineural hearing loss (SNHL)) earlier than the current golden standard pure-tone audiogram.This…
- Conditions
- Hearing Loss, Sensorineural, Cochlear Synaptopathy, Cochlear Hearing Loss
- Trial name
- EarDiTech (NCT06114680)
- Testing
- CochSyn test prototype, Universal Smart Box (USB)
- Where
- Belgium
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hearing Loss, Sensorineural, Cochlear Hearing Loss
Evaluation of the CochSyn Device in Clinical Practice
This study investigates a new type of auditory evoked brain potentials for the quantification and classification of peripheral hearing damage (The CochSyn Test).
- Conditions
- Hearing Loss, Sensorineural, Cochlear Hearing Loss, Cochlear Synaptopathy, DFNA9
- Trial name
- Earditech 2 (NCT07091071)
- Testing
- CochSyn device
- Where
- 3 sites in Belgium
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hidden Hearing Loss, Cochlear Synaptopathy
Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss
It is known that the underlying problem in Hidden Hearing Loss (HHL) is cochlear synaptopathy (CS) and that low-spontaneous-rate auditory nerve fibers play an important role in this pathology.
- Trial name
- NCT07230236
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Noise Exposure, Noise-induced Hearing Loss
Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss
The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia devices for preservation of sensory structures in the cochlea after noise exposure. The main aims of the study are: 1.
- Conditions
- Noise Exposure, Noise-induced Hearing Loss, Noise; Adverse Effect, Mild Therapeutic Hypothermia
- Trial name
- NCT06729632
- Testing
- Cold pack-delivered mild therapeutic hypothermia
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Restorear Devices LLC
Ototoxicity, Drug-Induced
Diagnostic of Various Ototoxicity Induced by Cancer Treatment
Visit the clinic once every 2 weeks for checkups and tests The goal of this clinical trial is to learn if systematic hearing tests (eg fonctional assesment, electrophysiology and seric biomarkers) can diagnose hidden hearing loss…
- Trial name
- BIO-OTOTOX (NCT06490029)
- Testing
- Auditory, vestibular and electrophysiological investigations, Biologic investigations; seric proteins
- Where
- France
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées