Clinical trials: High BP
Chronic Kidney Disease
Patient-driven Management of BP in CKD
The proposed research will evaluate if patients managing their blood pressure medications under the guidance of a clinical pharmacist works better to lower blood pressure than patients monitoring their blood pressure at home and…
- Trial name
- NCT05546099
- Testing
- Self-management of BP medications, Self-monitoring of home BP
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- VA Office of Research and Development
Pre-hypertension
Different Dosages of Bioactive Wheat Peptides and Blood Pressure Level and CVD Risk Biomarkers in Healthy Subjects
In this study we will assess the effects of bioactive peptide rich wheat products on blood pressure and estimated cardiovascular disease risk.
- Trial name
- NCT02197910
- Testing
- Comparisons of two kind of pasta with low or high content of wheat bioactive peptides (sequence Low->High), Comparisons of two kind of pasta with low or high content of wheat bioactive peptides (sequence High->Low)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Myocardial Infarction, Hypertension
Reducing Blood Pressure in Patients With High Cardiovascular Risk
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services healthcare system.
- Conditions
- Myocardial Infarction, Hypertension, Stroke
- Trial name
- BP-REACH (NCT05937685)
- Testing
- BP REACH Intervention
- Where
- 4 sites in United States
- Volunteers
- 546 people
- Sponsor
- University of Southern California
Cardiovascular Health, Cardiovascular Risk Factor
The Potassium Supplementation Study
This study will test whether potassium supplementation can reduce the deleterious effect of a high sodium diet on blood vessel function, blood pressure reactivity and autonomic nervous system function in apparently healthy adults.
- Trial name
- NCT05887622
- Testing
- Potassium chloride supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Healthy
Study to Assess the Safety, Tolerability, and Pharmacokinetics of REGN5381 (an NPR1 Agonist) in Adult Humans
The primary objective of the study is to evaluate the safety and tolerability of single intravenous (IV) doses of REGN5381 in healthy normotensive and otherwise healthy hypertensive adults.
- Trial name
- NCT04506645
- Testing
- REGN5381
- Where
- 2 sites in Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Chronic Kidney Disease, Diabetes
Improving Chronic Disease Management With Pieces
ICD-Pieces (Parkland Intelligent e-Coordination and Evaluation System) trial is a National Institutes of Health (NIH) Healthcare Systems(HCS) Collaboratory demonstration project to improve management of patients with a triad of…
- Conditions
- Chronic Kidney Disease, Diabetes, Hypertension, High BP
- Trial name
- ICD-Pieces (NCT02587936)
- Testing
- Collaborative Model of Primary care and Subspecialty care
- Where
- 4 sites in United States
- Volunteers
- 18,268 people
- Sponsor
- University of Texas Southwestern Medical Center
Asymptomatic Atrial Fibrillation
Subclinical Atrial Fibrillation Home Monitoring in Hypertensive Patients
Atrial fibrillation is a highly prevalent and incidental arrhythmia, often asymptomatic, and frequently detected incidentally or in association with a stroke.
- Trial name
- NCT07058831
- Testing
- Home ECG monitoring
- Where
- Argentina
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Research Center Rosario British Sanatorium
Hypertension, Cardiovascular Disease
Detecting and Treating High Blood Pressure in Aboriginal Population and Low and Middle Income Countries
Heart disease and stroke are the number one killers world-wide. When someone has hypertension, the constantly elevated blood pressure damages their blood vessels and the organs that they supply blood to.
- Conditions
- Hypertension, Cardiovascular Disease, Diabetes
- Trial name
- DREAM-GLOBAL (NCT02111226)
- Testing
- SMS text messaging
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- Sunnybrook Health Sciences Centre
Glaucoma, Hypertension
Know Your Pressures NYC
Dr. Lisa A. Hark (PI and Study Chair) and an interdisciplinary team have designed "Know Your Pressures NYC" to conduct blood pressure (BP)/glaucoma screenings in adults age 40+ to identify undiagnosed and/or uncontrolled…
- Conditions
- Glaucoma, Hypertension, Glaucoma, Suspect, Elevated Blood Pressure
- Trial name
- NCT05992415
- Testing
- Virtual Automated Navigator Intervention with Health Education, Usual Care
- Where
- United States
- Volunteers
- 7,085 people, healthy volunteers welcome
- Sponsor
- Columbia University
Blood Pressure, High Blood Pressure
Remote Dietary Counseling to Promote Healthy Diet and Blood Pressure
American College of Cardiology/American Heart Association (ACC/AHA) hypertension guidelines recommend lifestyle modification for patients with elevated blood pressure.
- Conditions
- Blood Pressure, High Blood Pressure, Dietary Modification, Overweight and Obesity
- Trial name
- NCT03700710
- Testing
- Self-Guided Approach, Dietitian-led Approach
- Where
- 2 sites in United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Hypertension (HTN), Hypertension ,Pregnancy
REmote Physical ACtivity Intervention for High Blood Pressure Postpartum
The purpose of this intervention is to help new mothers who had elevated blood pressure during pregnancy become more physically active after birth. The investigators will connect data from FitBits to the electronic health record.
- Conditions
- Hypertension (HTN), Hypertension ,Pregnancy, Physical Activity
- Trial name
- REACH BP (NCT07127731)
- Testing
- Patient Portal Messaging, FitBit EHR Linkage
- Volunteers
- 60 people
- Sponsor
- Northwestern University
High Blood Pressure
OPTImizing Precision of Hypertension Care to Maximize Blood Pressure Control Pilot (OPTI-BP Pilot)
Hypertension (HTN) is a major risk factor for coronary heart disease (CHD), heart failure, kidney failure and stroke. Disparities in HTN prevalence, treatment and control in the US have persisted for decades.
- Trial name
- NCT02814552
- Testing
- HTN PRA App, Blood Sample
- Where
- 3 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Florida
Hypertension
Trial of Low and High Intensity Strategies to Maintain BP Control
The long-range goal of this research is to advance understanding of long-term blood pressure (BP) control in patients with uncontrolled hypertension (HTN).
- Trial name
- NCT00760552
- Testing
- High Intensity Intervention, Low Intensity Intervention, All- 6 month pharmacist intervention
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- US Department of Veterans Affairs
Hypertension, Healthy
Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
(1) To compare cuff-less wrist wearable radial artery blood pressure measurements utilizing ViTrack(developed by Dynocardia) to the cuff based commercially available blood pressure device, in healthy volunteers with normal or…
- Trial name
- NCT04835857
- Testing
- ViTrack, Oscillometric BP Device, Auscultatory cuff
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Dynocardia, Inc
Healthy Sedentary Adults With BP <140/90
Cardiovascular Effects of High-Intensity Interval Training (HIIT)
The purpose of this study is to determine the effect of high-intensity interval training (HIIT) in comparison to moderate-intensity continuous training (MCT) on blood pressure, blood vessel function, and blood pressure reactivity.
- Trial name
- NCT03602170
- Testing
- High-Intensity Interval Training, Moderate-Intensity Continuous Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Delaware
Moderate to High-risk Noncardiac Surgery
Hypotension Prediction Index (HPI) SMART-BP Trial
A multicenter, randomized comparison of intraoperative hemodynamic management with or without a protocolized strategy utilizing Hypotension Prediction Index (HPI) software guidance during moderate-to-high-risk noncardiac surgery.
- Trial name
- NCT05105477
- Testing
- AcumenTM HPI Software Feature, Non-protocolized Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 407 people
- Sponsor
- Edwards Lifesciences
Elevated Blood Pressure, Habitual Sleep Duration of Less Than or Equal to 7 Hours
Sleep Technology Intervention to Target Cardiometabolic Health
The goal of this study is to test the efficacy of a behavioral sleep extension intervention on sleep duration, cardio-metabolic disease risk factors, and health behaviors among adults with elevated blood pressure/hypertension and…
- Trial name
- STITCH (NCT04766424)
- Testing
- Sleep extension intervention, Health education
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Conditionally Healthy Persons, Persons With a High Body Mass Index
Medico-ecological Monitoring ((CSM, MCTQ, SPAQ, PSQI, HRV, Spirometry; Anthropometry, BP) of the Different Population Groups (Students, Schoolchildren, Volunteers) in North Caucasus
Observational Clinical Trial of the chronotype, sleep quality, seasonal pattern, behavioral time preferences, the functional state of the body's regulatory systems and respiratory systems in individuals of different age groups…
- Trial name
- NCT04851080
- Testing
- Heart Rate Variability, Spirometry, Testing of psycho-physiological functions using four questionnaires
- Where
- Russia
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Vladikavkaz Scientific Center of the Russian Academy of Sciences
Non-cardiac Surgical, Intensive Care Unit (ICU)
The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial
The purpose of this study is to compare measurements of blood pressure (BP) and fluid responsiveness between the Philips AMC and invasive radial arterial line in surgical patients.
- Trial name
- HIPULSE (NCT06895590)
- Testing
- Philips Advanced Monitoring Cuff (i.e. AMC)
- Where
- 4 sites in United States, Germany
- Volunteers
- 205 people
- Sponsor
- Philips Clinical & Medical Affairs Global
High Blood Pressure
Behavioral Economics Trial To Enhance Regulation of Blood Pressure (BETTER-BP)
BETTER-BP (Behavioral Economics Trial To Enhance Regulation of Blood Pressure) is a phase II, single-center, prospective, pragmatic randomized clinical trial within the New York City Health and Hospitals (NYC-H+H) system and NYU…
- Trial name
- BETTER-BP (NCT04114669)
- Testing
- Control Condition, Regret Lottery
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- NYU Langone Health