Clinical trials: High Blood Pressure, open to volunteers
Pregnancy, Preeclampsia
Effects of Progressive Muscle Relaxation Exercise and Finger Grip Exercise on Stress, Anxiety, Fatigue, Sleep Quality, and Physiological Parameters in Pregnant Women With Preeclampsia
The aim of this study is to examine the effects of progressive muscle relaxation exercise and finger grip exercise on stress, anxiety, sleep quality, fatigue and physiological parameters in preeclamptic pregnant women.
- Trial name
- NCT07630623
- Testing
- Progressive Muscle Relaxation Exercise, Finger Grip Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hatice Nur Nefes Pala
Uncontrolled Hypertension
Remote Hypertension Management for Black Patients
This study will compare two approaches for managing hypertension in Black patients with uncontrolled blood pressure (BP). One approach will include home BP telemonitoring supported by a pharmacist and a community health worker.
- Trial name
- RHYTHM-B (NCT06527794)
- Testing
- RHYTHM (Remote Hypertension Tracking Help Management), Enhanced usual care (UC)
- Where
- United States
- Volunteers
- 864 people
- Sponsor
- Wake Forest University Health Sciences
Pulmonary Hypertension, Interstitial Lung Disease (ILD)
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
This is a Phase 2, open-label, multi-center clinical study to evaluate the safety and tolerability of inhaled mosliciguat in participants with pulmonary hypertension associated with interstitial lung disease (PH-ILD) on a…
- Conditions
- Pulmonary Hypertension, Interstitial Lung Disease (ILD), Lung Diseases, Vascular Diseases
- Trial name
- NCT07333183
- Testing
- inhaled mosliciguat, Dry Powder Inhaler
- Where
- 13 sites in United States
- Volunteers
- 20 people
- Sponsor
- Pulmovant, Inc.
Open Angle Glaucoma, Primary Open Angle Glaucoma
Topical Insulin for Glaucoma (TING2)
This study evaluates the safety and preliminary efficacy of topical sterile human insulin eye drops (EYED-002) in patients with open-angle glaucoma.
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Low Tension Glaucoma, Pigmentary Glaucoma
- Trial name
- NCT07619482
- Testing
- EYED-002 Low Dose (721 U/mL topical insulin), EYED-002 High Dose (1442 U/mL topical insulin), EYED-002 (highest tolerated dose, 12-month)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Prehypertension
A Clinical Trial of an Herbal Liquid Supplement - 'DBPS' for Managing Blood Pressure
Prehypertension is a clinical condition characterized by systolic blood pressure (SBP) readings between 120 and 139 mmHg and/or diastolic blood pressure (DBP) readings between 80 and 89 mmHg, as per the Joint National Committee…
- Trial name
- NCT07629570
- Testing
- DBPS
- Where
- 4 sites in India
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Eetho Brands, Inc
Preeclampsia (PE) Risk, Preeclampsia
Hyperspectral Imaging for Prediction of Preeclampsia
Preeclampsia is a hypertensive pregnancy disorder that can quickly lead to serious, potentially life-threatening outcomes for both the mother and the fetus.
- Trial name
- HIPPA (NCT07106294)
- Where
- Germany
- Volunteers
- 1,430 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Hypertension, Renal Insufficiency
Food Frequency Questionnaire to Assess Sodium Intake
EvalSel can precisely assess the salt intake of hospitalized patients in nephrology and cardiology or in medical consultation. It can determine salt consumption to the nearest gram.
- Trial name
- EVALSEL (NCT05533645)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Lille
Diabetes Mellitus, Hypertension
A Study to Evaluate the Efficacy and Safety of Dapagliflozin in Patient With Type 2 Diabetes Mellitus and Hypertension
The purpose of this clinical trial is to evaluate the efficacy and safety of dapagliflozin in patient with type 2 diabetes mellitus and hypertension
- Trial name
- NCT05970237
- Where
- South Korea
- Volunteers
- 9,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Glaucoma, Ocular Surface Disease
Ocular Surface Disease in Glaucoma Patients on Long-Term Therapy
This cross-sectional study aims to determine the prevalence and severity of ocular surface disease among adult patients with glaucoma receiving long-term topical antiglaucoma medications.
- Conditions
- Glaucoma, Ocular Surface Disease, Dry Eye
- Trial name
- NCT07841912
- Volunteers
- 55 people
- Sponsor
- Assiut University
Intracranial Hemorrhage, Hypertensive, Craniotomy Tumor Removal Surgery
Comparison of Post-Craniotomy Blood Pressure Targets
The goal of this pragmatic clinical trial is to learn if a more intensive or more liberal blood pressure target after surgery is more effective in improving patient outcomes for adults undergoing craniotomy for removal of a brain…
- Trial name
- COMPETE (NCT07093151)
- Testing
- Target SBP <160mmHg, Target SBP <140 mmHg
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Vanderbilt University Medical Center
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hypertension
Transcutaneous Electrical Acupoint Stimulation on Blood Pressure
This study will be conducted in patients with high-normal blood pressure and grade 1 hypertension and will be divided into two phases.
- Trial name
- NCT06537167
- Testing
- Transcutaneous electrical acupoint stimulation
- Volunteers
- 120 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Hypertension, Primary Hypercholesterolaemia
To Evaluate the Efficacy and Safety of Co-administrated HODO-2224-1 and HODO-2224-2 in Patients With Essential Hypertension and Primary Hypercholesterolemia
A Multicenter, Randomized, Double-blind, Active-controlled, Parallel group, Phase 3 trial to Evaluate the Efficacy and Safety of Co-administrated HODO-2224-1 and HODO-2224-2 in Patients with Essential Hypertension and Primary…
- Trial name
- HODO-2224 (NCT06646354)
- Testing
- Ezetimibe/Rosuvastatin/Candesartan/Amlodipine, Candesartan/Amlodipine, Candesartan/Rosuvastatin/Ezetimibe
- Where
- South Korea
- Volunteers
- 125 people
- Sponsor
- Hyundai Pharm
Gestational Hypertension, Preeclampsia (PE)
Postpartum CO Rehabilitation
Some women who develop high blood pressure during pregnancy, such as gestational hypertension or preeclampsia, may continue to have slightly or moderately high blood pressure after giving birth.
- Trial name
- NCT06920537
- Testing
- Postpartum Cardio-obstetric Rehabilitation Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Type 2 Diabetes, Hypertension
A Randomized, Double-blind, Multi-center, Active-controlled, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of THP-00101, THP-00102, and THP-00103 in Subjects With T2DM and Essential Hypertension
[Primary Objective] To demonstrate the superiority of the change in mean sitting systolic blood pressure (MSSBP) and hemoglobin A1c (HbA1c)on week 12 of the combination therapy of THP-00101 (dapagliflozin 10 mg) and THP-00102…
- Trial name
- THP-001-031 (NCT06647745)
- Testing
- THP-00101, THP-00102, THP-00103
- Where
- 2 sites in South Korea, Thailand
- Volunteers
- 221 people
- Sponsor
- THPharm Corp.
Idiopathic Intracranial Hypotension, Venous Sinus Stenosis
Stent Implantation Versus Medical Therapy for Idiopathic IntracraniaL Hypertension (SIMPLE)
The aim of this study is to assess the efficacy of stent implantation versus medical therapy on idiopathic intracranial hypertension with venous sinus stenosis.
- Trial name
- NCT05707442
- Testing
- Stent Implantation, Acetazolamide-based medical therapy, Weight loss
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Beijing Tiantan Hospital
Pulmonary Hypertension
Database for Clinical and Anamnestic Data in Pulmonary Hypertension
Pulmonary hypertension (PH) is defined as a pulmonary arterial mean pressure (meanPAP) ≥ 25 mmHg measured in the right heart catheterization. There are different forms of PH defined in the classification of Dana Point 2008.
- Trial name
- NCT01607502
- Where
- Austria
- Volunteers
- 900 people
- Sponsor
- Medical University of Graz
Hypertension
Comparison of Office and Cuffless Ambulatory Blood Pressure-Guided Management in Patients With Hypertension
Hypertension is a major risk factor for cardiovascular and cerebrovascular diseases, including stroke and myocardial infarction.
- Trial name
- CUFFLESS (NCT07770477)
- Testing
- Cuffless ambulatory blood pressure-guided management, Office blood pressure-guided management
- Where
- 9 sites in South Korea
- Volunteers
- 3,000 people
- Sponsor
- Seoul National University Hospital
Uncontrolled Hypertension
Netrod-Pilot Study of Renal Denervation With NetrodTM Sixelectrode Radiofrequency RDN System
This single-arm, non-randomized, open-label investigation aims to collect safety and efficacy data of the CE-Marked Netrod™ RDN System in treating European patients with primary hypertension in the absence of anti-hypertensive…
- Trial name
- NCT07061054
- Testing
- Netrod™ six-electrode radiofrequency renal denervation system
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Glaucoma
Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP)
Background Glaucoma is a multifactorial, chronic, and progressive eye disease characterized by the irreversible loss of retinal ganglion cells (RGCs).
- Trial name
- NCT07006194
- Testing
- Nicotinamide Tablet
- Where
- 3 sites in Italy
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
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