Clinical trials: High Flow Oxygenation
Apneic Oxygenation
Apneic Oxygenation Via Nasal Cannulae: 15 L/Min vs High-Flow
This is a randomized clinical trial investigating the utility of apneic oxygenation via nasal cannulae in the post-induction setting for the purpose of prolonging the safe apneic time.
- Trial name
- NCT02755389
- Testing
- 0 L/min oxygen via conventional nasal cannulae, 15 L/min oxygen via conventional nasal cannulae, 60 L/min oxygen via high-flow nasal cannulae
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Nova Scotia Health Authority
Hypoxia, Pars Plana Vitrectomy
Influence of HFNO on Spontaneous Breathing Support in Patients of Different ASA Risk During Moderate Multimodal Analgo-sedation for Pars Plana Vitrectomy
Pars plana vitrectomy is minimally invasive endoscopic procedure which is usually performed in moderate analgo-sedation given by anesthesiologist combined with topical anesthesia and regional eye anesthesia (retrobulbar or…
- Conditions
- Hypoxia, Pars Plana Vitrectomy, Respiratory Complications
- Trial name
- NCT04055077
- Testing
- Low-flow nasal oxygenation (LFNO) ASA I, Low-flow nasal oxygenation (LFNO) ASA II, Low-flow nasal oxygenation (LFNO) ASA III
- Where
- Croatia
- Volunteers
- 176 people
- Sponsor
- University of Split, School of Medicine
Hypoxemia, Esophageal Cancer
High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients
Hypoxia is the most common adverse event during propofol sedation for gastrointestinal endoscopy. The STOP-BANG questionnaire is a widely used, simple assessment tool for screening obstructive sleep apnea (OSA) risk.
- Conditions
- Hypoxemia, Esophageal Cancer, Gastric Cancer (Diagnosis), Colon Cancer
- Trial name
- NCT07155330
- Testing
- High-flow nasal cannula
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhejiang University
Anesthesia Morbidity
HIFLO ENDO-High Flow Nasal Cannula in GI Endoscopy
Millions of patients undergo upper GI endoscopy in the United States each year. A large number of these patients have anesthesia to assist with their comfort during the procedure.
- Trial name
- NCT03028688
- Testing
- High flow nasal cannula oxygen
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Anesthesia, General, Apnea
High Flow Nasal Cannula for Safe Apnea
This is a prospective randomized controlled trial comparing high flow nasal cannula and buccal oxygenation as method of oxygenation during apnea in children.
- Trial name
- NCT04849520
- Testing
- High flow nasal cannula, Buccal oxygenation
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Hospital
Obesity
Effect of Different-Flow High-Flow Nasal Cannula Versus Traditional Face Mask Oxygenation on Safe Apnea Time in Obese Patients
Obesity is a growing global health problem, and patients with obesity are at higher risk of hypoxemia during induction of general anesthesia.
- Trial name
- NCT07843810
- Testing
- Face Mask, High-Flow Nasal Cannula
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The First People's Hospital of Lianyungang
Apneic Oxygenation
Apneic Oxygenation in the Emergency Department
Apneic oxygenation is a process of delivering continuous oxygen during direct laryngoscopy. Nasal cannulas are used for the purpose of oxygenation; for delivering either low flow or high flow oxygen but haven't been tested in…
- Trial name
- ApOxED (NCT04242537)
- Testing
- High flow nasal cannula oxygen delivery, Low flow nasal cannula oxygen delivery
- Volunteers
- 30 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Laryngeal Disease
Hemodynamic Effects of Apnoeic Oxygenation With High-flow Nasal Oxygen in Adults Undergoing Laryngeal Surgery
During apnoeic oxygenation there is a continuous raise in carbon dioxide with subsequent respiratory acidosis. The hypercapnia and respiratory acidosis have several dose-related effects on both the systemic and the pulmonary…
- Trial name
- CAPOX (NCT06316063)
- Testing
- Apnoeic oxygenation with high-flow nasal oxygen, Mechanical ventilation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Region Stockholm
Anesthesia, General, Pulmonary Atelectasis
High-flow Nasal Oxygenation During Preoxygenation and Atelectasis
Atelectasis after induction of general anesthesia is common even in healthy patients and is clinically problematic, especially in obese patients.
- Trial name
- NCT06205212
- Testing
- high-flow nasal oxygen, facemask
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Patients With Acute Hypoxemic Respiratory Failure
Wean Early With HFNCO vs NPPV in Patients With AHRF
The main purpose of the present study is to verify whether, as compared with conventional weaning, early weaning with high-flow nasal cannula oxygenation or noninvasive positive pressure ventilation may more effective in…
- Trial name
- NCT03171935
- Testing
- High-Flow Nasal Cannula Oxygenation, Noninvasive Positive Pressure Ventilation, Conventional weaning
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Beijing Chao Yang Hospital
Brain Death
Validation of the Apnea Test Performed by High-flow Oxygen Therapy in Patients With Clinical Brain Death
Brain death is a clinical and paraclinical diagnosis established in a known etiological context. It involves the irreversible destruction of cerebral functions in a beating-heart individual.
- Trial name
- APNEAFLOW (NCT05950178)
- Testing
- Apnea test under high-flow oxygenation
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Hypoxia
The 90% Effective Flow of High Flow Nasal Oxygenation (HFNO) During Sedated Bronchoscopy
Patients undergoing sedated bronchoscopy were randomized into six groups (10 Liters/minute [L/min], 20 L/min, 30 L/min, 40 L/min, 50 L/min, 60 L/min). The primary outcome was the incidence of hypoxemia.
- Trial name
- HFNO (NCT05298319)
- Testing
- high flow nasal cannula
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Zhejiang Cancer Hospital
Pediatric Surgery, Rapid Sequence Induction
High-flow Nasal Cannula Oxygenation During Rapid Sequence Induction in Children
This randomised study aims to compare the utilization of high-flow humidified nasal oxygenation (HFNO) with standard care, using apnoeic facemask oxygenation, during rapid sequence induction (RSI) of anesthesia in young children.
- Trial name
- OPTINECK (NCT05063084)
- Testing
- Optiflow - HFNO, Classic
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia Induction
Oxygenation Procedure for Obese Patients During Intubation in the Operating Room
Obesity is a risk factor for difficult intubation, with an incidence of up to 15.5%, and difficult mask ventilation. Obesity also reduces the functional residual capacity (FRC) of the lungs, the main reservoir of oxygen during…
- Trial name
- POP-OVNI (NCT06914401)
- Testing
- NIV (Non Invasive Ventilation) and HFNO (High Flow Nasal Oxygen), NIV (Non Invasive Ventilation)
- Where
- 5 sites in France
- Volunteers
- 124 people
- Sponsor
- Clinique Pasteur
Anesthesia, Oxygen
PreOxygenation In RSI Anesthesia
Pre-oxygenation with high-flow nasal cannula oxygen has been evaluated in a limited number of studies and seems to be better than traditional preoxygenation with a tight fitting mask.
- Trial name
- PRIOR (NCT02794532)
- Testing
- High-flow nasal cannula
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Acute Respiratory Failure
Comparing High-flow Nasal Cannula Oxygen and Noninvasive Ventilation to Standard Oxygenation in Non-selected ICU Patients Admitted for Hypoxemic ARF
The goal of this clinical trial is to determine whether one of the two oxygenation or ventilation strategies (NIV and/or HFNO) is superior to standard oxygen to reduce 28-day mortality rate in hypoxemic acute respiratory failure…
- Trial name
- KISS (NCT05812911)
- Testing
- Standard oxygen, HFNO, NIV
- Where
- France
- Volunteers
- 1,470 people
- Sponsor
- University Hospital, Montpellier
Intersticial Lung Disease
Can High-Flow Oxygen Therapy Improve Oxygenation During Exercise in ILD Patients?
Objectives: 1.- To compare the level of oxygenation achieved during muscular training with conventional oxygen systems (nasal cannulas) versus nasal High-flow oxygen therapy.
- Trial name
- NCT03287713
- Testing
- oxygen therapy
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Comparison of Non-invasive Oxygenation Strategies in Patients Admitted for Covid-19 Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) is the main clinical presentation of SARS-CoV-2 (Covid-19) infected patients admitted in Intensive Care Unit (ICU).
- Trial name
- SONIC-19 (NCT04725084)
- Testing
- Use of High Flow Nasal Cannula alone, Use of Non-invasive Ventilation, Use of Continuous Positive Airway Pressure
- Where
- 4 sites in France
- Volunteers
- 355 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Postoperative Atelectasis, Bariatric Surgery Candidate
Can the Effects of High Flow Nasal Cannula Oxygenation on Postoperative Atelectasis be Evaluated With Lung Ultrasound
Evaluate the effects of high-flow nasal oxygen therapy on atelectasis in the perioperative period by lung ultrasound (LUS) in bariatric surgery patients.
- Conditions
- Postoperative Atelectasis, Bariatric Surgery Candidate, Ultrasound Therapy; Complications
- Trial name
- NCT03828513
- Testing
- High flow nasal cannula oxygen is applied, High flow nasal cannula oxygen is not applied
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
High Flow Nasal Cannula, Body Roundness Index
High Flow Nasal Cannula and Mask Oxygenation in Patients With Visceral Obesity Undergoing Sedated Gastroscopy
During sedated gastroscopy, the insertion of the fiberscope and gastric distension required to perform the examination may induce respiratory depression, airway obstruction, and decreased chest wall compliance.
- Trial name
- NCT07159022
- Testing
- High Flow Nasal Cannula Oxygenation, Face Mask Oxygenation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital