Clinical trials: High Insulin Requirements
Type1diabetes
Comparison of Low, Moderate and High Carbohydrate Diet on Insulin Requirements and Metabolic Control in Type 1 Diabetes
The scientific basis for dietary recommendations in type 1 diabetes is almost lacking, with the current recommendations being based on type 2 diabetes studies.
- Trial name
- DANCE (NCT03761186)
- Testing
- traditional diabetes diet, moderately low carbohydrate diet, strictly low carbohydrate diet
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Anneli Björklund
Type 1 Diabetes
Mobile Application-delivered Resistance Program for Children and Adolescents With Type 1 Diabetes (Diactive-1)
This project involves a two-arm randomized controlled trial (RCT) designed to assess the feasibility, acceptability, and preliminary efficacy of a mobile application aimed at prescribing resistance training for children and…
- Trial name
- Diactive-1 (NCT06048757)
- Testing
- Diactive-1 application
- Where
- 2 sites in Spain
- Volunteers
- 62 people
- Sponsor
- Fundacion Miguel Servet
Type 2 Diabetes, Insulin Resistance
PK/PD Study of U-500 Regular Insulin
The purpose of this study is to learn more about how U500 regular insulin can be effectively be used to treat type 2 diabetes. Most insulin treated patients with type 2 diabetes take U100 insulin, but if they require large doses…
- Conditions
- Type 2 Diabetes, Insulin Resistance, High Insulin Requirements
- Trial name
- NCT02148250
- Testing
- U-500 insulin, 100 syringe units, U-500 insulin, 200 syringe units
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Minnesota
Type 1 Diabetes Mellitus
Does Protein and Fat Content of Meal Increase Glucose Concentrations
The study investigated the effects of fat protein counting (CFP) in addition to carbohydrate (CARB) counting for calculating prandial insulin dosage on blood glucose profile in patients with type 1 diabetes (T1D) on basal-bolus…
- Trial name
- NCT03333525
- Testing
- Calculation of insulin dosages for different meals
- Volunteers
- 30 people
- Sponsor
- TC Erciyes University
Congenital Hyperinsulinism
Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia
The primary aim of this study is to evaluate the effect of Exendin (9-39) on glucose requirements to maintain euglycemia in pediatric patients with congenital hyperinsulinism (CHI) who have failed medical therapy.
- Trial name
- NCT00835328
- Testing
- Exendin (9-39), Vehicle
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Diva De Leon
Type 1 Diabetes (T1D)
Stretching and Diabetes
Diabetes mellitus is a persistent disease characterized by alterations in glucose metabolism due to insufficient insulin production or decreased sensitivity to insulin.
- Trial name
- STREDIB (NCT06774105)
- Testing
- Static Stretching
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- University of Palermo
Diabetes Mellitus, Type 2, Insulin Resistance
Effects of a Plant-Based Diet on Insulin Requirements and Obesity Markers in Obese Adults With T2DM
This is a crossover study utilizing a Dietary Approaches to Stop Hypertension (DASH) diet and a whole-food, plant-based diet among subjects with type 2 diabetes who require insulin.
- Conditions
- Diabetes Mellitus, Type 2, Insulin Resistance, Obesity, Nutritional and Metabolic Disease
- Trial name
- NCT04048642
- Testing
- DASH, Whole-Food, Plant-Based
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Rochester