Clinical trials: High Perianal Fistula
High Perianal Fistula
Comparative Study: Fistula Rerouting vs. LIFT for High Perianal Fistula
The goal of this clinical trial is to compare two different surgery methods for treating a complex type of anal fistula. This condition is an abnormal tunnel connecting the inside of the anus to the skin nearby.
- Trial name
- NCT07399353
- Testing
- Fistula Rerouting Technique, Ligation of Intersphincteric Fistula Tract
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
High Perianal Fistula, Fistula-in-Ano
Seton Re-routing for High Perianal Fistula
High perianal fistulae involve a significant portion of the external anal sphincter muscle, making standard surgical fistulotomy risky due to the potential for postoperative fecal incontinence.
- Conditions
- High Perianal Fistula, Fistula-in-Ano, High Anal Fistula
- Trial name
- NCT07850440
- Testing
- Seton Re-routing
- Volunteers
- 35 people
- Sponsor
- Assiut University
Anal Fistula, Rectal Fistula
Surgical Treatment of High Perianal Fistulas
Perianal fistula is a chronic phase of anorectal infection that occurs predominantly in the third and fourth decade of life. According to Parks classification fistulas have been divided into intersphincteric, transsphincteric…
- Trial name
- LIFTRAF (NCT01997645)
- Testing
- LIFT, RAF
- Where
- 3 sites in Czechia
- Volunteers
- 140 people
- Sponsor
- University Hospital Hradec Kralove
Anal Fistula, Fecal Incontinence
Gore-BioA Fistula Plug to Treat Transsphincteric Fistulas
This is a prospective clinical study on the efficacy of Gore-BioA fistula plug in high transsphincteric fistulas. Follow-up time is six months
- Conditions
- Anal Fistula, Fecal Incontinence, Surgery
- Trial name
- NCT01584752
- Testing
- Gore-BioA Fistula Plug
- Where
- 7 sites in Finland
- Volunteers
- 60 people
- Sponsor
- Central Finland Hospital District
High Anal Fistula
The Outcome of Combined Partial Fistulectomy or Fistulotomy and Cutting Seton Procedure in High Perianal Fistula
The aim of this study is to assess the effectiveness and suitability of the tight (cutting) seton as a surgical treatment of high anal fistula combined with partial fistulotomy or fistulectomy in a prospective study.
- Trial name
- NCT04796376
- Testing
- combined partial fistulectomy or fistulotomy and cutting seton procedure
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Assiut University
Post Operative Pain, Recurrence
Video-assisted Anal Fistula Treatment Versus Seton in the Management of High Peri Anal Fistula
Anal fistula is the most common Peri anal disease. It's a disease with an incidence of 9 in 100,000. Anal fistula is classified on the basis of its location into high and low anal fistula, above or below dentate line…
- Trial name
- NCT02313597
- Testing
- SETON, VAAFT
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Dr. SamiUllah
High Transsphincteric Perianal Fistula
Intersphincteric Approach to Perianal Fistula With High Risk for Postoperative Fecal Incontinence
.Rerouting operation takes the advantage of minimal recurrence rate as well as minimal incontinence that is associated with less sphincter division,It is indicated in patients with transsphincteric fistula in whom lay open is…
- Trial name
- NCT02994524
- Testing
- Rerouting technique for transsphincteric perianal fistula
- Volunteers
- 25 people
- Sponsor
- Yasser Mohamed Abdel-samii
High Transsphincteric Perianal Fistula
Ligation of Intersphincteric Fistula Tract Versus Cyanoacrylate Glue in One-Stage Management of High Transsphincteric Perianal Fistula
This study aims to compare ligation of the intersphincteric fistula tract with cyanoacrylate glue in the management of high transsphincteric perianal fistula.
- Trial name
- NCT07744672
- Testing
- Cyanoacrylate adhesive (Glubran 2), ligation of the intersphincteric fistula tract
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Perianal Fistula, Cryptoglandular Perianal Fistula
Stem Cell Fistula Plug in Cryptoglandular Perianal Fistulas (MSC-AFP)
The investigators propose to study the safety of autologous mesenchymal stromal cell transfer using a biomatrix (the Gore Fistula Plug) in a Phase I study using a single dose of 20 million cells.
- Trial name
- NCT02589119
- Testing
- MSC-AFP
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Perianal Fistula
This Study Compares the Conventional Cutting Seton Technique and a GLUBRAN®-Coated Seton in High Perianal Fistula Treatment. The Study Aims to Determine Whether the GLUBRAN®-Coated Seton Improves Healing, Reduces Postoperative Pain and Recurrence, and Better Preserves Anal Continence.
High anal fistula is a complex anorectal condition that can cause persistent pain, purulent discharge, recurrent infection, and a significant reduction in quality of life.
- Trial name
- NCT07676825
- Testing
- Glubran-coated Seton, Seton
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kasr El Aini Hospital