Clinical trials: High Risk Pregnancies
High-risk Pregnancy, Pregnancy
AI-Powered CURAᵀᴹ Application for Identifying At-Risk Pregnancies in Obstetric Management
It is important to identify high pregnancies early through screening so that appropriate care and intervention may be instituted.
- Conditions
- High-risk Pregnancy, Pregnancy, Antenatal Health
- Trial name
- CURAte (NCT06974188)
- Testing
- AI-risk Stratification
- Where
- Singapore
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Postpartum Hemorrhage
Tranexamic Acid and Ethamsylate For Preventing PPH in Patient Undergoing LSCS at High Risk For PPH
The aim of this study is to compare the effect of low dose of Tranexamic acid (1gm) and Ethamsylate (1gm) after prophylactic oxytocin administration versus placebo with prophylactic oxytocin given in the 2 minutes after child…
- Trial name
- NCT02604719
- Testing
- Tranexamic Acid and Ethamsylate
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ahmed Alanwar
Pre-Eclampsia, Gestational Diabetes
SMARThealth Pregnancy: Feasibility & Acceptability of a Complex Intervention for High-risk Pregnant Women in Rural India.
Background: Pregnancy-related conditions including hypertensive disorders of pregnancy (HDPs) and gestational diabetes mellitus (GDM) carry independent risks for future cardiovascular disease in women.
- Conditions
- Pre-Eclampsia, Gestational Diabetes, Anemia
- Trial name
- NCT03968952
- Testing
- SMARThealth Pregnancy
- Where
- India
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Human Papillomavirus Infection, Self Sampling
HPV Typing Between Self- and Physician-sampled
Hygeia Touch Inc. developed a safe and comfortable vaginal self-sampling device "Hygeia Touch Self Sampling Kit for Women" to self-collect the vaginal discharge sample for high-risk Human Papillomavirus (hrHPV) detection.
- Conditions
- Human Papillomavirus Infection, Self Sampling, Vaginal Discharge
- Trial name
- NCT04472377
- Testing
- Self sampling kit for collecting discharge from vaginal fornix
- Where
- 3 sites in Taiwan
- Volunteers
- 1,210 people, healthy volunteers welcome
- Sponsor
- Hygeia Touch Inc.
Gestational Diabetes Mellitus, Pregnancy Complications
Gestational Diabetes Mellitus (GDM) in Pregnant Women
The purpose of the trial is to discover and predict the development of GDM of pregnant women in their first trimester.
- Trial name
- NCT05265741
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Long Island University
Cervical Cancer
Acceptability and Validity of Self Sampling for High Risk HPV Detection Among Women in Maharashtra
The study goals are, 1. To determine the test characteristics (sensitivity, specificity, positive predictive value, negative predictive value, false positivity rates, false negativity rates) of health personnel collected and self…
- Trial name
- HPV (NCT03386695)
- Testing
- Education by Pamphlets, Health education programme
- Where
- India
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
Abortion, Spontaneous
High Molecular Weight Hyaluronic Acid, α-lipoic Acid, Magnesium, Vitamin B6 and Vitamin D, in the Prevention of Spontaneous Abortion
The study aims to verify if the association of high molecular weight hyaluronic acid, α-lipoic acid (ALA), magnesium, vitamin B6 and vitamin D, reduces the risk of miscarriage in patients at risk.
- Trial name
- NCT05449171
- Testing
- high molecular weight hyaluronic acid, α-lipoic acid (ALA), magnesium, vitamin B6 and vitamin D
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lo.Li.Pharma s.r.l
Pre-Eclampsia
The Effectiveness of Aspirin on Preventing Pre-eclampsia
This study will explore the effectiveness of low-dose aspirin on preventing pre-eclampsia in high-risks pregnant women by comparing the incidence of pre-eclampsia and pregnancy outcomes.
- Trial name
- NCT04656665
- Testing
- Aspirin
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Pregnancy
Effectiveness of Online-Based "Pregnant Women Care Cadres" Intervention on Husband Support in Early Detection of High Risk in Medan Maimun Area
The goal of this quasi-experimental study is to evaluate whether an online-based "Caring for Pregnant Women" intervention delivered through community health cadres can improve husband support in the early detection of high-risk…
- Trial name
- NCT07430033
- Testing
- Online-Based "Caring for Pregnant Women" Intervention Through Community Health Cadres to Enhance Husband Support in Early Detection of High-Risk Pregnancy
- Where
- Indonesia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Siti Saidah Nasution
Trisomy 13, Trisomy 18
High Risk Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our proprietary algorithm method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278874
- Where
- 4 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Gestational Diabetes Mellitus
Lifestyle Intervention and Prevention of Gestational Diabetes Mellitus
The number of women with gestational diabetes mellitus (GDM) had been increasing. Maternal GDM has a great impact on both the health of the mothers and the offspring.
- Trial name
- NCT02368600
- Testing
- Lifestyle modification program
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Ovarian Cancer, Breast Cancer
Lynne Cohen Consortium Project: Multi-Center Database/Registry
Goals of this registry: 1.1 To collect and store very limited demographic information (age, birthdate, race and ethnicity), limited cancer risk and breast and ovarian disease history, as well as limited family history of breast…
- Trial name
- NCT00776958
- Testing
- Questionnaire
- Where
- 4 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pregnancy, High Risk
Remote Cardiotocography Telemonitoring Within High-risk Pregnancy Care
The overall aim of this research proposal is to explore the feasibility and acceptability of home antenatal maternal-fetal monitoring technology within a high-risk pregnancy group.
- Conditions
- Pregnancy, High Risk, Telemonitoring, Telemedicine
- Trial name
- NCT07124325
- Testing
- Pregnabit Pro device and PregnaOne platform
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Fetal Macrosomatia, Lipid Metabolism Disorders
Influence of TyG Index and TG/HDL-C Ratio on Fetal Macrosomia
Metabolic disorders that can occur during pregnancy, in particular disorders of lipid metabolism and insulin resistance, can have a detrimental effect on pregnancy and the fetus.
- Conditions
- Fetal Macrosomatia, Lipid Metabolism Disorders, Hyperlipidemias
- Trial name
- NCT06463990
- Testing
- TyG index
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
PreTerm Birth
New Tool to Predict Risk of Spontaneous Preterm Birth in Asymptomatic High-risk Women
The QUIPP tool integrates information of obstetrical history, quantitative fetal fibronectin (qfFN) and cervical length to predict the risk of sPTB in asymptomatic high-risk women.
- Trial name
- NCT03062020
- Testing
- QUIPP
- Where
- 2 sites in Spain
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona