Clinical trials: High Risk Surgery
Postoperative Atelectasis, Bariatric Surgery Candidate
Can the Effects of High Flow Nasal Cannula Oxygenation on Postoperative Atelectasis be Evaluated With Lung Ultrasound
Evaluate the effects of high-flow nasal oxygen therapy on atelectasis in the perioperative period by lung ultrasound (LUS) in bariatric surgery patients.
- Conditions
- Postoperative Atelectasis, Bariatric Surgery Candidate, Ultrasound Therapy; Complications
- Trial name
- NCT03828513
- Testing
- High flow nasal cannula oxygen is applied, High flow nasal cannula oxygen is not applied
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Parkinson Disease
Subthalamic Nucleus Connectivity in Parkinson's Disease With Ultra-high Field Magnetic Resonance Imaging
The purpose of this study is to investigate the segregation of the subthalamic nucleus into its motor and non-motor regions in patients with Parkinson's disease and healthy controls with the aid of ultra-high field magnetic…
- Trial name
- NCT01981577
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Attention Concentration Difficulty, Neck Pain
Microbreaks in the OR to Mitigate High Physical and Mental Demands
Will targeted intraoperative exercises performed by surgeons during surgery, mitigate high physical and mental demands while enhancing performance during surgical procedures?
- Conditions
- Attention Concentration Difficulty, Neck Pain, Back Pain, Shoulder Pain
- Trial name
- OR-STRETCH (NCT02565394)
- Testing
- Micro Break with Dynamic Exercise Activities
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Goal-directed Fluid Therapy, Hemodynamics Instability
Multi-center Trial of Goal-directed Fluid Management Based on Pulse Pressure Variation Monitoring
Background: Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. It was tested this hypothesis in a multi-center study.
- Conditions
- Goal-directed Fluid Therapy, Hemodynamics Instability, High-risk Surgery, Pulse-pressure Variation
- Trial name
- GDTPPV (NCT03128190)
- Testing
- Pulse pressure variation monitoring
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo
Ischemia Coronary Artery Origin
Thoracic Epidural Reduces Risks of Increased Left Ventricular Mass Index During Coronary Artery Bypass Graft Surgery
Increased left ventricular mass index (LVMI) results from aortic valve lesions as an adaptive mechanism to help limit systolic wall stress and preserve ejection fraction (EF).
- Trial name
- NCT03719248
- Testing
- thoracic epidural
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ahmed Said Elgebaly,MD
Perioperative/Postoperative Complications, Aerobic Capacity
SHAPE Test for Preoperative Risk Stratification
This study is looking at whether a simplified exercise test called the SHAPE-HF cardiopulmonary testing system can be used before surgery in older adults.
- Trial name
- SHAPEPAT (NCT05743673)
- Testing
- Shape II
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Yale University
Coronary Artery Disease, Coronary Stenosis
Transit Time Flow Measurement in Coronary Surgery
Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
- Trial name
- COLLATERAL (NCT06471062)
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Failed Back Surgery Syndrome, Complex Regional Pain Syndrome (CRPS)
A Study to Confirm the Safety of High Frequency DRG Stimulator in Patients With Chronic Lower Limb Pain
This study is a prospective, single-arm, open label, single center pilot study to confirm the safety of a ultrahigh frequency DRG stimulator in patients with chronic lower limb pain. The actual trial length is 5 days.
- Trial name
- NCT03285113
- Testing
- GiMer Medical MN 1000 External Stimulator
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- GiMer Medical
Analgesia
Ultrasound Guided Block for Postoperative Analgesia in Arthroscopic Shoulder Surgery
This study aimed to compare the efficacy of high thoracic-ESPB with shoulder block as analgesic options for arthroscopic shoulder surgery. Primary outcome: 24-hour analgesic consumption.
- Trial name
- NCT06202430
- Testing
- High Thoracic Erector Spinae Plane Block, Shoulder Block
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Abdominal Surgery, Spirometry
Chest Physiotherapy on Immediate Postoperative in Patients Submitted to High Abdominal Surgery
Abdominal surgical procedures can increase risks of pulmonary complications.The aim of the study was to evaluate the benefits of an early intervention of chest physiotherapy during immediate post-operative in patients submitted…
- Conditions
- Abdominal Surgery, Spirometry, Chest Physiotherapy
- Trial name
- NCT00596778
- Testing
- chest physiotherapy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Myocardial Injury, Non-cardiac Surgery
Hemodynamics and Myocardial Injury After Non-cardiac Surgery
The incidence of myocardial injury after non-cardiac surgery (MINS) is approximately 12-15% and is associated with an increased risk of 30-day mortality, 1-year mortality, and 2-year major vascular events.
- Conditions
- Myocardial Injury, Non-cardiac Surgery, Complication,Postoperative, High-sensitivity Troponin
- Trial name
- MINS (NCT05188001)
- Testing
- Not an Interventional Study
- Where
- Canada
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Low-flow Anesthesia
High vs. Low Flow Sevoflurane Anesthesia in Pediatric Laparoscopic Surgery: Recovery, Hemodynamics, and Cost Comparison
The primary objective of our study is to compare the effects of different flow rates of the routinely used inhalation agent, sevoflurane, on postoperative recovery times in pediatric patients undergoing elective laparoscopic…
- Trial name
- NCT06676969
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Familial Cancer, BRCA1-Associated Protein-1 (BAP1) Mutations
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome
Background: A germline mutation is a change to a person s genes that is carried through their DNA. These mutations can be passed on from parents to their offspring.
- Conditions
- Familial Cancer, BRCA1-Associated Protein-1 (BAP1) Mutations, Tumor Predisposition Syndrome (TPDS), Mesothelioma
- Trial name
- NCT04431024
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Hip Fracture Surgeries, High Risk Population of Hip Fractures
A Decision Support Tool for Common Surgical Fixations of Hip Fractures
This study aims to improve how patients, families, and healthcare professionals work together to make important medical decisions, especially in cases involving hip fractures.
- Conditions
- Hip Fracture Surgeries, High Risk Population of Hip Fractures, Decision Surrogate of Hip Fixations
- Trial name
- NCT07909876
- Testing
- IDeA for Hip Fracture, Non-IDeA for hip fracture
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Suicide
REACH VET Implementation Program Evaluation
The VA's Office of Mental Health and Suicide Prevention implemented an new program to increase suicide prevention outreach for Veterans at highest risk for suicide.
- Trial name
- REACH VET (NCT03280225)
- Testing
- External facilitation
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development