Clinical trials: High Sensitive C-reactive Protein (hsCRP)
Periodontal Diseases
"Effect of CPA/EE Drug on Periodontal Tissue and hsCRP Levels in PCOS Patients With Gingivitis
PCOS is a widely reported condition among young female population and anti-androgen agents are increasingly being used as part of the medical management of such cases.
- Trial name
- NCT05657171
- Testing
- cyproterone Acetate/Ethinyl Estradiol Combination
- Where
- India
- Volunteers
- 47 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Coronary Artery Disease, Percutaneous Coronary Intervention
Different Doses of Colchicine on hsCRP
Colchicine reduced atherothrombotic cardiovascular events in the COLCOT and LoDoCo2 studies. US Food and Drug Administration approved colchicine as the first anti-inflammatory drug for cardiovascular diseases on June, 2023.
- Trial name
- NCT06078904
- Testing
- Colchicine 0.5 MG, Colchicine 0.375 MG, Colchicine 0.25 MG
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Cardiovascular Disease
Clinical Study to Assess High-DHA Fish Oil on Biomarkers of Cardiovascular Disease Risk in Adults on Statin Therapy
The objective of this study is to determine the acute and chronic [4-week] effects of a high-DHA fish oil supplement on fasting and post-prandial (post-meal) biomarkers of cardiovascular disease risk, in adults on Statin therapy.
- Trial name
- NCT01690312
- Testing
- Fish Oil
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Schizophrenia, Cognitive Dysfunction
Supportive Psychotherapy as Adjunct to Risperidone for Cognitive Function and Inflammation in Schizophrenia
This study examined whether adding structured supportive psychotherapy to risperidone treatment is more effective than risperidone alone in improving cognitive function and reducing inflammation in patients with schizophrenia.
- Conditions
- Schizophrenia, Cognitive Dysfunction, Inflamation
- Trial name
- SUPPORT-SCZ (NCT07477301)
- Testing
- Structured Supportive Psychotherapy, Risperidone 2 mg
- Where
- Indonesia
- Volunteers
- 46 people
- Sponsor
- Hasanuddin University
Chest Pain, Coronary Artery Disease
Risk Markers in the Acute Coronary Syndromes
The main aim of this trial is to assess the long-term prognostic value of different types of Factor XIIa in an unselected, single center series of 871 chest pain patients admitted to the emergency unit, employing blood samples…
- Conditions
- Chest Pain, Coronary Artery Disease, Unstable Angina Pectoris, Myocardial Infarction
- Trial name
- RACS (NCT00521976)
- Where
- Norway
- Volunteers
- 871 people
- Sponsor
- Helse Stavanger HF
Gestational Diabetes
Relationship of Reduced Arterial Stiffness and Hs-CRP With GDM.
Research hypotheses 1. The arterial stiffness in pregnant women with gestational diabetes is reduced compared to healthy pregnant women. 2.
- Trial name
- NCT05479565
- Testing
- venous blood sample for determining the value of highly sensitive C-reactive C protein from serum
- Where
- Bosnia and Herzegovina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Mostar
Atherosclerosis, Type 2 Diabetes
High-sensitivity C-reactive Protein and United Kingdom Prospective Diabetes Study (UKPDS) Risk Score in Type 2 Diabetes
The UKPDS risk score is recommended to assess global risk for future coronary heart disease (CHD) events in primary prevention. Recently, high-sensitivity C-reactive protein (hsCRP) has emerged as a strong independent risk factor…
- Trial name
- NCT01099865
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Korea University
Heart Transplant, Periodontitis
Effect of Non-Surgical Periodontal Therapy on Inflammation in Heart Transplant Recipients
Heart transplant recipients frequently exhibit chronic low-grade systemic inflammation, which can contribute to allograft dysfunction and cardiovascular complications.
- Conditions
- Heart Transplant, Periodontitis, Gingivitis, Systemic Inflammation
- Trial name
- NCT07791927
- Testing
- Full-mouth periodontal debridement
- Volunteers
- 20 people
- Sponsor
- Baskent University
Thalassemia
Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients
Every year, 100,000 neonates are born with hemoglobinopathies around the world. Thalassemia is the most common heterogeneous disease of the human being .
- Trial name
- NCT03170245
- Testing
- Interleukin-6, HsC-RP, Adiponectin level
- Where
- Egypt
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
COVID-19
Effect Of Calcitriol On Neutrophil To Lymphocytes Ratio And High Sensitivity C-Reactive Protein Covid-19 Patients
This research is a study that compares the administration of calcitriol with the outcomes of COVID-19 patients
- Trial name
- NCT05765617
- Testing
- Calcitriol
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Universitas Sebelas Maret
Obstructive Sleep Apnea, Coronary Heart Disease
Long-term Effects of CPAP on Lipidemia and Hs-CRP Levels in OSA Patients
The increased risk of atherosclerotic morbidity and mortality in patients with obstructive sleep apnea (OSA) has been linked to hypertension, insulin resistance, dyslipidemia, and systemic inflammation.
- Trial name
- NCT02127177
- Testing
- Continuous Positive Airway Pressure Ventilator
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
NLRP3, hsCRP
Effect of Inflammasome Inhibitor on hsCRP in Patients After PCI
Coronary artery disease (CAD) comprises the major contributor to a global epidemic of cardiovascular disease. Patients with CAD undergoing percutaneous coronary intervention (PCI) have a high-risk for adverse clinical outcomes.
- Conditions
- NLRP3, hsCRP, Percutaneous Coronary Intervention
- Trial name
- NCT05130892
- Testing
- Colchicine, Tranilast, Oridonin
- Where
- 2 sites in China
- Volunteers
- 132 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Secondary Hyperparathyroidism, End Stage Renal Disease
A Study to Follow-up Patients With End Stage Renal Disease Undergoing Hemodialysis, Receiving Selective Vitamin D Receptor Activator's for Prevention and Treatment of Secondary Hyperparathyroidism
The aim of this post-marketing observational study is to obtain further data on the long term use, safety and efficacy of selective Vitamin D Receptor Activator's as it is prescribed in the normal clinical setting and according…
- Trial name
- NCT01149291
- Where
- 22 sites in Turkey (Türkiye)
- Volunteers
- 511 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Diabetes Mellitus, Type 2, Apical Periodontitis
Association of Apical Periodontitis With Systemic Level of Inflammatory Markers : A Longitudinal Intervention Study
While cross-sectional studies have reported a significant association between diabetes and Apical Periodontics, prospective studies are scarce.
- Trial name
- NCT05814965
- Testing
- endodontic treatment in the form of root canal treatment, endodontic treatment, assessment of inflammatory marker
- Where
- India
- Volunteers
- 280 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Ischemic Stroke
hsCRP in Japan Statin Treatment Against Recurrent Stroke (J-STARS hsCRP)
Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A(HMG-CoA) reductase can play a role in preventing recurrent vascular events from ischemic heart disease patients, whose mechanism consists in not only the reduction of serum…
- Trial name
- NCT00361699
- Testing
- Statin
- Where
- 2 sites in Japan
- Volunteers
- 1,095 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Biomarkers
DIGIPREDICT-Physio-DE
The study aims to investigate short-term physiological and biochemical inflammatory and cardiocirculatory biomarker kinetics in heart failure patients, using the DIGIPREDICT Physiopatch device - an investigational device that…
- Trial name
- NCT05886569
- Testing
- DIGIPREDICT Physiopatech
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Periodontitis
STUDY ON THE EFFECTS OF PERIODONTAL TREATMENT ALONG WITH THE USE OF ANTIBIOTICS OVER HIGH SENSITIVE C-REACTIVE PROTEIN. RANDOMIZED CONTROLLED CLINICAL TRIAL.
Human periodontitis is a group of highly prevalent oral inflammatory diseases and infections with relatively easy treatment and preventive features.
- Trial name
- NCT01906450
- Testing
- Scaling and root planing plus Azithromycin
- Where
- Colombia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Acute Coronary Syndrome
High Sensitive C-reactive Protein to Albumin Ratio in Acute Coronary Syndrome
assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients
- Trial name
- NCT06673381
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Sohag University
Stable Angina, Heart Failure
Association Between Inflammatory Biomarkers in CVD Patients on Empagliflozin.
The association of novel inflammatory biomarkers with cardiovascular diseases is still obscure. The present study aimed to investigate the relationship of various inflammatory biomarkers with the existence as well as the extent…
- Trial name
- NCT05911724
- Testing
- Group I Healthy, CAD-Empagliflozin 10 mg once daily for 6 months before the beginning of the study, HF-Empagliflozin 10 mg once daily for 6 months before the beginning of the study
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Damanhour University
Periodontitis, Polycystic Ovary Syndrome
Evaluation of Periodontal Status and hsCRP Levels in Females With PCOS on CPA/EE Combination Drug Regimen
PCOS is a widely reported condition among young female population and anti-androgen agents are increasingly being used as part of the medical management of such cases.
- Conditions
- Periodontitis, Polycystic Ovary Syndrome, Gingivitis
- Trial name
- NCT05021861
- Testing
- Cyproterone Acetate, Ethinyl Estradiol Drug Combination, FEMALE PATIENTS WITH PCOS, Control group
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak