Clinical trials: High Vasopressin
Critical Illness
Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU
Renal dysfunction is a frequent complication in patients admitted to intensive care units (ICUs), associated with high morbidity and mortality.
- Trial name
- NOVA-AKI (NCT06547892)
- Testing
- Vasopressin, 0,9% saline solution
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital do Coracao
Healthy Volunteer
A Phase 1, Randomized, Double-blind, Placebo-controlled Crossover Study of RG7314 on the Potential Regulation of Higher Brain Functions in Healthy Male Participants: Proof of Mechanism
This is a single site, randomized, double-blind, three period cross-over, placebo-controlled, proof of mechanism study in healthy male subjects.
- Trial name
- NCT02205073
- Testing
- RG7314 RD + AVP SD
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autosomal Dominant Polycystic Kidney Disease
High Water Intake in Polycystic Kidney Disease
DRINK is an open-label randomised controlled feasibility trial of high versus ad libitum water intake in ADPKD.
- Trial name
- DRINK (NCT02933268)
- Testing
- High water intake, Ad libitum water intake
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Meniere Disease
Vasopressin and V2 Receptor in Meniere's Disease
Summary: Some of sicknesses are well known to be provoked by inadequate adaptation to physical and/or psychogenic stress in their daily life.
- Trial name
- NCT00599560
- Testing
- vasopressin, V2 receptor and cyclic AMP
- Where
- Japan
- Volunteers
- 135 people
- Sponsor
- Osaka University
Dehydration, Diabetes Mellitus, Type 2
INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers
Previous studies have indicated increased vasopressin due to hypertonic saline infusion impairs glucose regulation. The current study will examine the effect of low water intake on glucose regulation.
- Trial name
- INDIGO-2 (NCT04076995)
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Glucose, High Blood
Hydration to Optimize Metabolism
This study evaluates hydration (1.5 L of water daily during 1 year) in the lowering of blood glucose concentration in adults with signs of dehydration (elevated levels of the vasopressin marker copeptin and high urine…
- Trial name
- H2O-metabolism (NCT03422848)
- Testing
- Water, general life style advice
- Where
- Sweden
- Volunteers
- 797 people, healthy volunteers welcome
- Sponsor
- Region Skane
Low Water Intake, High Vasopressin
The Hydration to Optimize Metabolism (H2O Metabolism) Pilot Study
This study evaluates increased hydration (1.5 L of water daily during 6 weeks) on top of habitual water intake in the lowering of the vasopressin marker copeptin and in the lowering of plasma glucose concentration in adults with…
- Trial name
- H2OMetaboPilot (NCT03574688)
- Testing
- Water
- Where
- Sweden
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Region Skane
Patients With End Stage Renal Disease on Hemodialysis
Effect of Plasma Sodium Concentration on Blood Pressure Regulators During Hemodialysis
Intradialytic hypotension (IDH) is a frequent and serious complication that may occur during hemodialysis treatment. The investigators and others have shown that the Hemocontrol biofeedback system is associated with improved…
- Trial name
- NCT03578510
- Testing
- Hemocontrol hemodialysis, Standard hemodialysis
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- University Medical Center Groningen