Clinical trials: High-Flow Nasal Cannula
High-flow Nasal Cannula Oxygen
Evaluating High-flow Nasal Cannula Oxygen Therapy Through LUS During Weaning
Respiratory distress after extubation is associated with increased morbidity and mortality. Its multifactorial pathophysiology causes a loss of pulmonary aeration during the weaning process, the clinical translation being…
- Trial name
- NCT03384394
- Testing
- high-flow nasal cannula oxygen, Conventional oxygen therapy
- Volunteers
- 250 people
- Sponsor
- lu xiao
Pregnancy Related, Anesthesia
Pre-oxygenation With High-flow Nasal Cannula in Caesarian Section Under General Anesthesia
The investigators and other groups have demonstrated that high-flow nasal oxygen used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask.
- Conditions
- Pregnancy Related, Anesthesia, Oxygen Deficiency, Cesarean Section Complications
- Trial name
- PRIOROB (NCT04711317)
- Testing
- Nasal high flow oxygen
- Where
- 4 sites in Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska University Hospital
Bronchiolitis
HFNC Versus NCPAP/ NPPV in Infants With Severe Bronchiolitis
The purpose of the study was to test the null hypothesis that there is no difference between nasal continuous positive airway pressure / nasal positive pressure ventilation (NCPAP/NPPV) and high flow nasal cannula (HFNC) devices…
- Trial name
- NCT04650230
- Testing
- nasal continuous positive airway pressure / nasal positive pressure ventilation (NCPAP/NPPV) and high flow nasal cannula (HFNC) devices
- Volunteers
- 268 people
- Sponsor
- Children's Hospital of Tunis
Endometrium; Hypertrophy, Cervix, Anesthesia
High Flow Oxygen During Operative Hysteroscopy.
High-flow nasal cannula (HFNC) oxygen therapy represents an open circuit ventilation system that uses flows up to 70 L/min of 100% oxygen through the Optiflow THRIVETM device (Fisher and Paykel Healthcare Ltd, Auckland, New…
- Conditions
- Endometrium; Hypertrophy, Cervix, Anesthesia, Apnea, Postanesthetic
- Trial name
- HOPE (NCT05550584)
- Testing
- Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE)., LMA
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
High-flow Nasal Cannula, Ultrasound Evaluation
Ultrasound Evaluations of Diaphragm and Intercostal Muscle to Predict the Failure of High-Flow Nasal Cannula Therapy
The study aims to predict the failure of High-flow Nasal Cannula oxygenation therapy by ultrasound evaluation of diaphragm and intercostal muscle contraction during the first 24 hours.
- Conditions
- High-flow Nasal Cannula, Ultrasound Evaluation, Diaphragm and Intercostal Muscle
- Trial name
- NCT06375538
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Zhongshan Hospital
Newborn Respiratory Distress Syndrome
HHHFNC (Heated Humidified High-Flow Nasal Cannula) Versus NCPAP for Respiratory Distress Syndrome of Prematurity
Preterm infants ranging from 29+0 to 36+6 weeks+days are randomly assigned to one of the following treatments as non invasive respiratory support if they develop mild to moderate Respiratory Distress Syndrome within 72 hrs from…
- Trial name
- NCT02570217
- Testing
- HHHFNC, NCPAP
- Where
- Italy
- Volunteers
- 316 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Hypoxia
Efficacy of High-flow Nasal Oxygen in Preventing Hypoxia During Gastrointestinal Endoscopy: a Retrospective Cohort Study
During painless gastroscopy, the occurrence of hypoxia is a critical concern, especially under intravenous anesthesia using propofol.
- Trial name
- NCT06710613
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Fengli Liu
Acute Respiratory Failure Requiring Reintubation
High-flow Nasal Cannula Oxygen Therapy With or Without NIV During the Weaning Period
Prospective multicenter randomized controlled open-label trial comparing 2 strategies of oxygenation during the post-extubation period in ICU patients at high risk of extubation failure.
- Trial name
- HIGH-WEAN (NCT03121482)
- Testing
- HFNC, NIV
- Where
- France
- Volunteers
- 650 people
- Sponsor
- Poitiers University Hospital
Postoperative Complications, Atelectasis
High-Flow Nasal Cannula After Major Abdominal Surgery to Prevent Postoperative Pulmonary Complications
Major abdominal surgery is associated with a substantial risk of early postoperative pulmonary complications, including atelectasis, hypoxemia, pneumonia, and increased need for respiratory support.
- Conditions
- Postoperative Complications, Atelectasis, Pneumonia, Respiratory Insufficiency
- Trial name
- NCT07528404
- Testing
- High flow nasal cannula (HFNC), Standard oxygen therapy
- Where
- South Korea
- Volunteers
- 580 people
- Sponsor
- Uijeongbu St. Mary Hospital
Bariatric Surgery Candidate, Atelectasis, Postoperative Pulmonary
Ventilation Distribution After Bariatric Surgery
Obese patients have an increased risk of developing post-operative respiratory complications due to their comorbidities. They have a restrictive ventilatory defect with reduction of lung volumes and expiratory flow limitation…
- Trial name
- NCT03975348
- Testing
- High flow nasal cannula, Continuous positive airway pressure, Facemask
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Trieste
Coronavirus Infection, COVID
COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss
Prone positioning is an established intervention in mechanically ventilated acute respiratory distress syndrome (ARDS) patients, with demonstrated reductions in mortality.
- Conditions
- Coronavirus Infection, COVID, Severe Acute Respiratory Syndrome, Respiratory Failure
- Trial name
- COVAYDE (NCT04395144)
- Testing
- Awake Prone Positioning, Standard care
- Where
- 5 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Hôpital de Verdun
Extubation Failure
Postextubation High-flow Therapy vs Noninvasive Ventilation in Obese or at High-risk Patients
The main aim is to demonstrate whether reintubation rate is lower with preventive conditioned noninvasive ventilation (NIV) rather than with High-flow oxygen therapy (HFOT) in obese intermediate-risk patients and in high-risk…
- Trial name
- HINFOR (NCT04125342)
- Testing
- Preventive Conditioned NIV Therapy after planned extubation, Preventive HFOT after planned extubation
- Where
- 2 sites in Spain
- Volunteers
- 326 people
- Sponsor
- Hospital Virgen de la Salud
Critical Care, High-flow Nasal Cannula Oxygen
Effect of High-flow Nasal Cannula Oxygen on Lung Volumes Determined by Electrical Impedance Tomography
Effect of High-flow nasal cannula oxygen on end-expiratory lung volumes determined by electrical impedance tomography
- Conditions
- Critical Care, High-flow Nasal Cannula Oxygen, Electrical Impedance Tomography, End Expiratory Lung Volume
- Trial name
- OXIDIA (NCT02186288)
- Testing
- High-flow nasal cannula oxygen
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Preterm Infant
High Flow Nasal Cannula Versus Nasal Intermittent Positive Pressure (NIPPV) in Preterm Infants
The aim of this study is to compare the effectiveness of Heated Humidified High Flow Nasal Cannula (HHHFNC) versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) in preventing intubation when used as primary respiratory…
- Trial name
- VAPORAM (NCT03853161)
- Testing
- Vapotherm, NIPPV
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- Carmel Medical Center
Cardiogenic Pulmonary Edema
HIgh Flow Versus NIV for Acute Cardiogenic PuLmonary Oedema With Acute Respiratory Failure in an ED
The purpose of this study is to compare non invasive ventilation to high flow nasal cannula oxygen for the management of patients admitted with an acute respiratory failure due to an acute cardiogenic pulmonary edema.
- Trial name
- NCT04971213
- Testing
- Non invasive ventilation, High-flow nasal cannula heated and humidified oxygen
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Poitiers University Hospital
Sleep Apnea, Obstructive
Heated Humidified High Flow Nasal Cannula for Children With Obstructive Sleep Apnea
The purpose of this study is to determine whether heated humidified high flow nasal cannula (HHHFNC) is effective as a treatment of obstructive sleep apnea syndrome (OSAS) compared to continues positive airway pressure (CPAP)…
- Trial name
- NCT02515409
- Testing
- HHHFNC, CPAP
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Respiratory Failure
HFNC and NIV for COVID-19 Complicated by Respiratory Failure
Background: Patients with COVID-19 have a range of clinical spectrum from asymptomatic infection, mild illness, moderate infection requiring supplemental oxygen and severe infection requiring intensive care support.
- Trial name
- NCT04452708
- Testing
- HFNC
- Where
- Hong Kong
- Volunteers
- 26 people
- Sponsor
- Chinese University of Hong Kong
Burns
Comparison of High Flow vs Standard Nasal Cannula in Children With Burns Under Sedoanalgesia
The aim of this study is to investigate the positive effects of high-flow oxygen therapy on the reduction of airway adverse events and recovery time compared to conventional nasal oxygen therapy in pediatric burns treated with…
- Trial name
- NCT06663293
- Testing
- Conventional Nasal Cannula, High-flow nasal cannula, midazolam, ketamine, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Zeliha Alicikus
Chronic Obstructive Lung Disease, Respiratory Insufficiency
The Edi Level and Cardiopulmonary Function Between HHHFNC and Unheated Humidified High-Flow Oxygen Mask in COPD
Patients with COPD exacerbation usually need respiratory support after extubation. Recently, HHHFNC has been used in both adult and neonates with post-extubation respiratory support.
- Trial name
- NCT03811158
- Testing
- HHHFNC, UHFOM
- Where
- Taiwan
- Volunteers
- 2 people
- Sponsor
- Fu Jen Catholic University
Anesthesia, General, Apnea
High Flow Nasal Cannula for Safe Apnea
This is a prospective randomized controlled trial comparing high flow nasal cannula and buccal oxygenation as method of oxygenation during apnea in children.
- Trial name
- NCT04849520
- Testing
- High flow nasal cannula, Buccal oxygenation
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Hospital