Clinical trials: High-Flow Nasal Cannula
Hypoxemia
The Correlation Between Sleep Quality and Atrial Fibrillation Undergoing High-flow Nasal Cannula Oxygen (HFNC)
The investigators hypothesized that heated humidified high-flow nasal cannula oxygen(HFNC) along with high quality of sleep, in comparison with noninvasive positive pressure ventilation (NIV), could reduce the release of…
- Trial name
- NCT02713737
- Testing
- heated humidified high-flow nasal cannula, noninvasive ventilation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
COPD Exacerbation
High Flow Nasal Cannula vs NPPV in Moderate Chronic Obstructive Pulmonary Disease Exacerbation
For moderate AECOPD(pH<7.35), several guidelines have strongly recommended NPPV as standard therapy, which can reduce the rate of intubation and mortality.
- Trial name
- NCT03014869
- Testing
- High flow nasal cannula
- Where
- China
- Volunteers
- 351 people
- Sponsor
- China-Japan Friendship Hospital
RDS - Infants, TTN
Effect of Cannula Size on Oxygen Saturation During Nasal High Flow Therapy in Newborns
Treatment with nasal high flow therapy (NHF) is an increasingly popular method of respiratory support in newborns. Safe and effective use of NHF requires selection of an appropriate nasal prong-to-nares ratio because leak can…
- Trial name
- NCT04459429
- Testing
- Change of cannula size
- Where
- Armenia
- Volunteers
- 25 people
- Sponsor
- Erebouni Medical Center
Acute Hypoxemic Respiratory Failure
Comparison Between High-flow Nasal Cannula System and Non-invasive Ventilation in Acute Hypoxemic Respiratory Failure
Acute hypoxemic respiratory failure may require invasive mechanical ventilation. However, invasive mechanical ventilation is associated with a variety of complications.
- Trial name
- NCT01166256
- Testing
- Non-invasive ventilation, High flow nasal cannula system
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Asan Medical Center
Acute Respiratory Failure
High Flow Nasal Cannula in the Emergency Department
The aim of this study was to describe the changes in respiratory rate, heart rate and dyspnea, before and after using HFNC in patients presenting to our emergency department with ARF.
- Trial name
- HFNC (NCT03460119)
- Testing
- High Flow Nasal Cannula Oxygen
- Volunteers
- 43 people
- Sponsor
- Hospital Italiano de Buenos Aires
Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency
High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this study is to see if the Vapotherm High Flow Therapy (HFT) device is effective to provide breathing support to patients with Chronic Obstructive Pulmonary Disease or COPD.
- Trial name
- NCT00990119
- Testing
- Vapotherm High Flow Therapy, Non-invasive positive pressure ventilation
- Where
- United States
- Sponsor
- Vapotherm, Inc.
Lung Diseases, Interstitial
High Flow in Interstitial Lung Disease
This is a prospective, 6 week cross-over study on the effect of High flow nasal cannula (HFNC) delivered air in patients with interstitial lung disease (ILD), in need of ambulatory oxygen therapy.
- Trial name
- HiFloILD (NCT03816722)
- Testing
- Airvo2, Usual care
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Aalborg University Hospital
Carbon Monoxide Poisoning, Environmental Exposure
Utility of High Flow Nasal Cannula in CO Toxicity
determination of the half-life of COHb in CO-poisoned patients with high flow nasal oxygen therapy in the ED.
- Trial name
- NCT03342209
- Testing
- Fisher&Paykel AIRVO™ 2 High Flow Nasal Cannula Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kocaeli University
Acute Respiratory Failure With Hypoxia
High-flow Oxygen Therapy vs Non-invasive Ventilation: Comparison of Alveolar Recruitment in Acute Respiratory Failure
This physiological study showed an increase in regional ventilation with NIV but no difference in alveolar recruitment as compared to HFNC in patients with hypoxemic ARF.
- Trial name
- IRAvista (NCT04664322)
- Testing
- non invasive ventilation and high flow nasal canulae oxygen therapy
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Rouen
Chronic Obstructive Pulmonary Disease
Effects on Ventilation With NHF and Asymmetrical Nasal Cannulas
The aim of this controlled randomized crossover study is to compare the physiological effects of nasal high flow therapy (NHF) with 2 different nasal cannulas in patients with exacerbated chronic obstructive pulmonary disease…
- Trial name
- NHFDuet (NCT05676502)
- Testing
- AIRVO 2
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Kliniken Essen-Mitte
COPD
High Flow Nasal Cannula and Hypercapnia
In the present investigation, in 50 COPD with persistent hypercapnia after an acute exacerbation, the investigators want to assess the acceptability of HFNC and its effectiveness in further reducing the level of PaCO2, and to…
- Trial name
- NCT03759457
- Testing
- High Flow Nasal Cannula (AIRVO2)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Airway Disorder
Optimizing High Flow Nasal Cannula Oxygenation in Pediatric Airway Procedures
The purpose of this study is to investigate which flow rate (higher versus lower) is most effective at increasing apneic time and preventing greater than 5% drop in desaturation, as well as assessing transcutaneous carbon dioxide…
- Trial name
- NCT06947902
- Testing
- High flow, Low Flow
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Respiratory Failure, Respiratory Failure With Hypercapnia
Role of HFNC During FOB in Patients With Respiratory Failure
This prospective interventional study aims to evaluate the safety and efficacy of high-flow nasal cannula (HFNC) oxygen therapy during fiber-optic bronchoscopy in patients with respiratory failure.
- Trial name
- NCT07880964
- Testing
- High flow nasal canula
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Acute Bronchiolitis
Comparison of High Flow Nasal Cannula and Standard Face Mask Oxygen Therapy in Children With Bronchiolitis
The study aims to compare the efficacy of two different oxygenation methods on decrease respiratory rate, heart rate, and clinical respiratory score in children with moderate to severe bronchiolitis requiring oxygen therapy. 1.
- Trial name
- NCT04245202
- Testing
- HFNCOT, St-FMOT
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Ege University
Desaturation of Blood, Colonoscopy
The Use of High Flow Nasal Cannula, Standard Face Mask and Standard Nasal Cannula in Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal endoscopy with the patient under deep intravenous sedation.
- Trial name
- NCT03479905
- Testing
- Salter nasal cannula, Face mask, High Flow Nasal Cannula
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Texas Southwestern Medical Center
Deep Sedation, Oxygen Therapy
HFNC Vs LFNC in Patients with AF Undergoing RFCA Under Deep Sedation.
Oxygen supplementation through high flow nasal cannula (HFNC) may reduce the incidence of desaturation and hypoxemia during deep sedation at radiofrequency catheter ablation (RFCA procedures).This study is designed to test the…
- Conditions
- Deep Sedation, Oxygen Therapy, Radiofrequency Ablation
- Trial name
- NCT04842253
- Testing
- High flow nasal cannula
- Where
- Netherlands
- Volunteers
- 141 people
- Sponsor
- Maastricht University Medical Center
High-flow Nasal Cannula, Exercise Capacity
Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation
The purpose of this study is to compare the exercise capacity between high SpO2 (Minimum SpO2 94-96%) value during pulmonary rehabilitation and low SpO2 (Minimum SpO2 84-86%) value during pulmonary rehabilitation for the patients…
- Conditions
- High-flow Nasal Cannula, Exercise Capacity, Chronic Respiratory Failure, Optimal SpO2 Value
- Trial name
- NCT04481295
- Testing
- High-flow nasal cannula, Low SpO2
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
COPD Exacerbation
HFNC vs Nasal Cannula in Mild Chronic Obstructive Pulmonary Disease Exacerbation
For AECOPD patients, only 8% patients ventilated by noninvasive and invasive positive pressure ventilation. Nasal cannula is the most common pattern of oxygen therapy in mild AECOPD.
- Trial name
- NCT03003559
- Testing
- High flow nasal cannula
- Where
- China
- Volunteers
- 328 people
- Sponsor
- China-Japan Friendship Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Time Course of Respiratory Oscillometry Parameters During Nasal High-Flow Therapy in Stable Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) can affect the small airways and alter respiratory mechanics. Nasal high-flow therapy delivers warmed and humidified gas through nasal cannulas and may change airway resistance.
- Trial name
- NHFlOscillo (NCT07750613)
- Testing
- Heated Humidified Nasal High-Flow Therapy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- ADIR Association
Desaturation of Blood, Obesity
High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal (GI) endoscopy with the patient under deep sedation.
- Conditions
- Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea
- Trial name
- NCT03148262
- Testing
- The Comfort Flo system, The Salter nasal cannula
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Texas Southwestern Medical Center