Clinical trials: High-Flow Nasal Cannula
Respiratory Failure, Hypoxemia
High-flow Nasal Cannula vs. Helmet PSV vs. Helmet CPAP During Respiratory Failure
The investigators designed a cross-over, randomized trial to assess the physiological effects of helmet pressure support ventilation (PSV) and continuous positive airway pressure (CPAP) as compared to high-flow nasal cannula…
- Trial name
- HIGHFLOWHELMET (NCT04241861)
- Testing
- Respiratory support (High-flow oxygen therapy), Respiratory support (Helmet PSV), Respiratory support (Helmet CPAP)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Respiratory Distress Syndrome, Newborn
High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure for Respiratory Support of Preterm Neonates
This work is designed to: 1. Evaluate the efficacy of HHHFNC in comparison with nCPAP in preterm neonates. 2. Investigate hemodynamic changes associated with HHHFNC in comparison to nCPAP in preterm neonates during periods of…
- Trial name
- NCT04238273
- Testing
- Functional Echocardiography
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Ain Shams University
Endobronchial Ultrasound
HFNC Versus SOT During EBUS
Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) is a routine procedure that is performed to sample mediastinal lymph nodes.
- Trial name
- NOT-EBUS (NCT05425836)
- Testing
- Standard oxygen therapy, HFNC
- Where
- 2 sites in India
- Volunteers
- 300 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pneumonia-associated Acute Hypoxemic Respiratory Failure
Non-invasive Ventilation Versus High Flow Oxygen
The purpose of the study is to compare the efficacy of alternating Non Invasive Ventilation NIV and High Flow Oxygen HFO compared to High Flow Oxygen HFO alone on gas exchanges and prognosis in pneumonia-associated acute…
- Trial name
- HFO (NCT03758508)
- Testing
- High Flow Oxygen nasal cannula, Noninvasive ventilation
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Niguarda Hospital
Bronchiectasis
HFNC in Management of Bronchiectasis Exacerbation
Patients with Bronchiectasis experience exacerbations with hypercapnic respiratory failure associated with an increased respiratory workload that may require intensive care unit (ICU) admission due to the inability of the…
- Trial name
- NCT05741697
- Testing
- bi-level ventillation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
COVID-19, Acute Respiratory Failure
High Flow Nasal Cannula Versus High Velocity Nasal Insufflation in Covid-19
To compare the outcomes of HFNC and HVNI in COVID-19 patients with acute respiratory failure as regard need for mechanical ventilation, changes of arterial blood gases (ABG) parameters, duration of ventilatory support and delay…
- Trial name
- NCT05216640
- Testing
- High Flow Oxygen Therapy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Intubation;Difficult
Preoxygenation for Difficult Airway Management
Tracheal intubation in operating room for patients at risk of difficult intubation remains a critical event. The aim of this study is to determine whether Nasal High Flow Therapy by nasal cannula Optiflow® administered before and…
- Trial name
- PREOPTI-DAM (NCT03604120)
- Testing
- Preoxygenation with high flow therapy by nasal cannula, Preoxygenation by standard Facial mask
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Nantes University Hospital
Hypoxemia, Esophageal Cancer
High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients
Hypoxia is the most common adverse event during propofol sedation for gastrointestinal endoscopy. The STOP-BANG questionnaire is a widely used, simple assessment tool for screening obstructive sleep apnea (OSA) risk.
- Conditions
- Hypoxemia, Esophageal Cancer, Gastric Cancer (Diagnosis), Colon Cancer
- Trial name
- NCT07155330
- Testing
- High-flow nasal cannula
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhejiang University
High-flow Nasal Cannula, Oxygenation
High-Flow Nasal Oxygen for Preoxygenation in Emergency Surgery Patients With Full Stomachs
Patients with full stomachs face a high risk of regurgitation and aspiration under general anesthesia. To minimize the time between the loss of airway protective reflexes and successful tracheal intubation, rapid sequence…
- Conditions
- High-flow Nasal Cannula, Oxygenation, General Anesthesia, Induction Anesthesia
- Trial name
- HFNC (NCT06879600)
- Testing
- High-flow nasal cannula therapy application, Traditional facemask
- Where
- Vietnam
- Volunteers
- 200 people
- Sponsor
- Nguyen Dang Thu
Respiratory Failure
Lung Volume Change Between Noninvasive Positive Pressure Ventilation by Nasal Pillow and High Flow Nasal Cannula
The difference of lung volume change will be monitored by electrical impedance tomography before and after use of noninvasive positive pressure ventilation by nasal pillow and high flow nasal cannula in post-extubation patients.
- Trial name
- NCT02292992
- Testing
- Nasal Pillow CPAP
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Mackay Memorial Hospital
Post Extubation Respiratory Failure, Re-intubation
Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients
Post extubation respiratory failure occur in 30% of extubated patients. More than 50% of them required reintubation. Noninvasive positive pressure ventilation (NIV) had been reported as an effective tool to prevent post…
- Conditions
- Post Extubation Respiratory Failure, Re-intubation, Septic Shock, Severe Sepsis
- Trial name
- NCT03246893
- Testing
- Noninvasive positive pressure ventilation, High flow oxygen nasal cannula
- Where
- Thailand
- Volunteers
- 222 people
- Sponsor
- Mahidol University
Ventilatory Failure, Hypoxemic Respiratory Failure
PREdicting Failure of Non-inVasIve Ventilatory Support Using Non-invaSIve mONitoring in Non-intubated Patients With Acute Hypoxemic Respiratory Failure or Post-extubation Failure. The PREVISION Study
The goal of this observational study is to assess the potential non-invasive tools (e.g. regional ventilation, respiratory muscle response, lung mechanic's parameters) to identify the risk of failure when using high flow nasal…
- Conditions
- Ventilatory Failure, Hypoxemic Respiratory Failure, Weaning Failure, Respiratory
- Trial name
- PREVISION (NCT06716463)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Unity Health Toronto
Acute Respiratory Failure, Pneumonia
Predicting Success of HFNC: The Utility of the ROX Index
The purpose of the study was to describe early predictors and to develop a prediction tool that accurately identifies the need for mechanical ventilation in pneumonia patients with acute respiratory failure treated with High Flow…
- Trial name
- NCT02834325
- Testing
- mechanical ventilation
- Volunteers
- 201 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Patients With Acute Hypoxemic Respiratory Failure
Wean Early With HFNCO vs NPPV in Patients With AHRF
The main purpose of the present study is to verify whether, as compared with conventional weaning, early weaning with high-flow nasal cannula oxygenation or noninvasive positive pressure ventilation may more effective in…
- Trial name
- NCT03171935
- Testing
- High-Flow Nasal Cannula Oxygenation, Noninvasive Positive Pressure Ventilation, Conventional weaning
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Beijing Chao Yang Hospital
Lung Cancer
Prospective Study to Evaluate High Flow Nasal Cannula With Monitored Anesthesia Care During EBUS Bronchoscopy
Our objective is to assess whether the use of high flow nasal cannula (Vapotherm, Exeter, NH) with monitored anesthesia care (MAC) during an endobronchial ultrasound (EBUS) bronchoscopy procedure will lead to less procedure…
- Trial name
- NCT05203328
- Testing
- Vapotherm, Regular nasal canula
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- The Cooper Health System
Pediatric Surgery, Rapid Sequence Induction
High-flow Nasal Cannula Oxygenation During Rapid Sequence Induction in Children
This randomised study aims to compare the utilization of high-flow humidified nasal oxygenation (HFNO) with standard care, using apnoeic facemask oxygenation, during rapid sequence induction (RSI) of anesthesia in young children.
- Trial name
- OPTINECK (NCT05063084)
- Testing
- Optiflow - HFNO, Classic
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Failure
Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High-flow Nasal Cannula Oxygen.
Preoxygenation is routinely performed before endotracheal intubation. In the intensive care unit, preoxygenation is often accomplished using a nose-mouth mask.
- Trial name
- NCT01994928
- Testing
- Nose-mouth mask, High flow nasal cannula oxygen, Intubation
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Sleep Apnea
Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea
The participants whom undergo Polysomnography study (Sleep study) and are found to have mild, moderate or severe Obstructive Sleep Apnea (OSA) will have two consecutive titration nights.
- Trial name
- NCT05475119
- Testing
- Continuous Positive Airway Pressure (CPAP), High Flow Nasal Cannula (HFNC)
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Abdulaziz University
Covid19, Acute Respiratory Failure
Noninvasive Respiratory Support in COVID-19 (CATCOVID-AIR)
COVID-19 pneumonia can cause severe acute hypoxemic respiratory failure. The usefulness of noninvasive respiratory support (NIRS), by means of nasal high-flow oxygen (NHFO), continuous positive airway pressure (CPAP), or…
- Conditions
- Covid19, Acute Respiratory Failure, Corona Virus Infection
- Trial name
- CATCOVID-AIR (NCT04668196)
- Testing
- High-flow nasal cannula treatment, Continuous positive airway pressure (CPAP) treatment, Noninvasive ventilation treatment
- Where
- 10 sites in Spain
- Volunteers
- 367 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Preoxygenation, Anesthesia
High-Flow Nasal Cannula (HFNC) Preoxygenation in Obese Patients Undergoing General Anesthesia
This study aims to evaluate the effectiveness of the High Flow Nasal Cannula (HFNC) for the preoxygenation of obese patients undergoing a general anesthesia.
- Conditions
- Preoxygenation, Anesthesia, Obesity
- Trial name
- NCT03615417
- Testing
- High Flow Nasal Cannula (HFNC), Standard anesthesia FaceMask (FM)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Erasme University Hospital