Clinical trials: High-flow Anesthesia
Pulmonary Atelectasis, Postoperative Complications
poStoperative Anesthesia Care: Facial Mask vs Hfnc and Thoracic Ultrasound for Reduction of Atelectasis Incidence
The primary aim of this study is to assess the efficacy of post-operatory HFNC in reducing the incidence of hypoxemia after gynecological oncology surgery, compared to the standard application of O2 through a Venturi mask; The…
- Conditions
- Pulmonary Atelectasis, Postoperative Complications, Gynecologic Cancer, Anesthesia
- Trial name
- SAMURAI (NCT04566419)
- Testing
- HFNC - Airvo 2, Oxygen
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anesthesia Induction
Oxygenation Procedure for Obese Patients During Intubation in the Operating Room
Obesity is a risk factor for difficult intubation, with an incidence of up to 15.5%, and difficult mask ventilation. Obesity also reduces the functional residual capacity (FRC) of the lungs, the main reservoir of oxygen during…
- Trial name
- POP-OVNI (NCT06914401)
- Testing
- NIV (Non Invasive Ventilation) and HFNO (High Flow Nasal Oxygen), NIV (Non Invasive Ventilation)
- Where
- 5 sites in France
- Volunteers
- 124 people
- Sponsor
- Clinique Pasteur
Anesthesia, Hypoxia
Pre-oxygenation With High-flow Nasal Cannula in Adults During Rapid Sequence Induction Anesthesia
It has been demonstrated that Transnasal Humidified Rapid Insufflation Ventilatory Exchange used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask.
- Conditions
- Anesthesia, Hypoxia, Surgery, Acute
- Trial name
- PRIOR2 (NCT03516175)
- Testing
- High flow transnasal oxygen, Pre oxygenation using tight fitting facemask
- Where
- 6 sites in Sweden, Switzerland
- Volunteers
- 350 people
- Sponsor
- Karolinska University Hospital
Induction of General Anesthesia
Effect of High-flow Nasal Oxygenation on Gastric Insufflation in Children
This is a randomized controlled study to compare the incidence of gastric insufflation when using high-flow nasal oxygenation and facemask ventilation in pediatric patients.
- Trial name
- NCT06204653
- Testing
- HFNO group, MV group
- Volunteers
- 70 people
- Sponsor
- Ajou University School of Medicine
Esophageal Cancer, Postoperative Pulmonary Atelectasis
High Flow Nasal Cannula After Esophagectomy
This study will compare the effect of HFNC versus standard oxygen administration after elective esophagectomy for cancer.
- Conditions
- Esophageal Cancer, Postoperative Pulmonary Atelectasis, Postoperative Pneumonia, Postoperative Pneumothorax
- Trial name
- OSSIGENA1V (NCT05718284)
- Testing
- AIRVO2, STANDARD CARE
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- Cristian Deana
Hypoxemia During Surgery, Atelectasis
Usage of High Flow Nasal Cannula in Preventing Desaturations in Elderly Patients Going for Lower Limb Surgeries
To study the effect of high flow nasal cannula in comparisons with nasoprong used intraoperatively in patients oxygenation status
- Trial name
- NCT06054022
- Testing
- high flow nasal cannula, nasoprong oxyen 2Litres per minute
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Lung Collapse
HFNC for Induction During Bariatric Surgery Patients.
This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing…
- Trial name
- NCT03155711
- Testing
- HFNC group, Standard group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
High-flow Nasal Cannula, Oxygenation
High-Flow Nasal Oxygen for Preoxygenation in Emergency Surgery Patients With Full Stomachs
Patients with full stomachs face a high risk of regurgitation and aspiration under general anesthesia. To minimize the time between the loss of airway protective reflexes and successful tracheal intubation, rapid sequence…
- Conditions
- High-flow Nasal Cannula, Oxygenation, General Anesthesia, Induction Anesthesia
- Trial name
- HFNC (NCT06879600)
- Testing
- High-flow nasal cannula therapy application, Traditional facemask
- Where
- Vietnam
- Volunteers
- 200 people
- Sponsor
- Nguyen Dang Thu
Laparoscopic Cholecystectomy
Low Flow and High Flow Anesthesia on Thiol-Disulfide Homeostasis and IMA in Laparoscopic Cholecystectomy Surgery
Comparison of the Effects of Low Flow and High Flow Anesthesia on Thiol-Disulfide Homeostasis and Ischemia Modified Albumin in Laparoscopic Cholecystectomy Surgery In this study, our aim is to compare the effects of Low Flow and…
- Trial name
- İMA (NCT04926480)
- Testing
- low and high flow Anesthesia
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anesthesia, Oxygen
PreOxygenation In RSI Anesthesia
Pre-oxygenation with high-flow nasal cannula oxygen has been evaluated in a limited number of studies and seems to be better than traditional preoxygenation with a tight fitting mask.
- Trial name
- PRIOR (NCT02794532)
- Testing
- High-flow nasal cannula
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Foreign Bodies, Tumor
High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on apnea in patients undergoing general anesthesia with rigid bronchoscopy compared with standard anesthesia methods.
- Conditions
- Foreign Bodies, Tumor, Stenosis Trachea, Bronchus Tumour
- Trial name
- NCT03892408
- Testing
- Optiflow ™
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Obesity, Morbid
Preoxygenation With Optiflow™ in Morbidly Obese Patients is Superior to Face Mask
Optiflow™ may provide an opportunity to prolong apnea time in the morbidly obese patient population. This study will examine whether Optiflow can do this, and compare the pre-oxygenation with Optiflow to the pre-oxygenation…
- Trial name
- NCT03009877
- Testing
- Optiflow F&P 850™ System, facemask, Rocuronium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Atelectasis, Postoperative Pulmonary
End-Expiratory Lung Volume in Children Awakening From Propofol Anesthesia
The goal of this pilot randomized clinical trial is to test the effects of high flow nasal oxygen and head elevation during awakening from propofol anesthesia in pediatric patients undergoing airway surgery.
- Trial name
- NCT05821114
- Testing
- Head elevation_H, Supine_H, Head elevation_L
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Apnea, Respiration; Arrest
The Effect of High-flow Nasal Oxygen Flow Rate on Gas Exchange During Apnoea
Apnoeic oxygenation refers to oxygenation that occurs through the insufflation of oxygen into the lungs in the absence spontaneous respiration or positive pressure ventilation.
- Conditions
- Apnea, Respiration; Arrest, Anesthesia
- Trial name
- Apox-HFNO (NCT05124093)
- Testing
- Apnoeic oxygenation
- Where
- Ireland
- Volunteers
- 114 people
- Sponsor
- University College Hospital Galway
Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia
Comparison of the Efficacy of High-flow Nasal Oxygen Therapy and Facial Mask Ventilation on the Increase of the Oxygen Reserve Index During Anesthetic Induction
The purpose of this study is to compare the ability of oxygenation with high-flow nasal oxygen therapy and mask ventilation technique for induction of anesthesia in adult patients who are planning to undergo surgery under general…
- Trial name
- NCT04291339
- Testing
- High-flow nasal oxygen technique, Mask ventilation technique
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Yonsei University
Anesthesia, Airway Morbidity
Preoxygenation Using High Flow Oxygen : Efficacy and Tolerance in Healthy Volunteers
High flow nasal cannula oxygen has been proposed to perform preoxygenation in patients with acute respiratory failure requiring orotracheal intubation in intensive care units.
- Conditions
- Anesthesia, Airway Morbidity, Safety Issues
- Trial name
- PreOx-OHD (NCT03399695)
- Testing
- preoxygenation
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Laryngoscopy, Child
Airway Interventions During Intravenous Anesthesia in Children Undergoing Direct Laryngoscopy for Surgical Procedures Using High Flow Nasal Versus Low Flow Oxygen. A Pilot Study.(Flowkid)
The goal of this clinical trial is to evaluate possible differences in airway responses and interventions during intravenous anesthesia for direct laryngoscopy in children when comparing two oxygenation methods (conventional low…
- Conditions
- Laryngoscopy, Child, Oxygen Therapy
- Trial name
- NCT06037915
- Testing
- low flow oxygen with nasopharyngeal tube, high flow oxygen with OptiflowTM Nasal High Flow
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Tympanoplasty, Myringoplasty
NLR and Sevoflurane Use in Ear Surgeries: Flow Comparison
This retrospective study aims to compare the effects of low-flow and high-flow anesthesia techniques on intraoperative hemodynamics, neutrophil-to-lymphocyte ratio (NLR), and postoperative outcomes in patients undergoing…
- Conditions
- Tympanoplasty, Myringoplasty, Neutrophil-to-Lymphocyte Ratio, Low-flow Anesthesia
- Trial name
- ANFLUX (NCT07064642)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Eda KAZANÇ ÖZDEN
Apnea, Respiration; Arrest
Pre-oxygenation With Facemask Oxygen vs High-flow Nasal Oxygen vs High-flow Nasal Oxygen Plus Mouthpiece Oxygen
Pre-oxygenation increases oxygen reserves in the body to reduce the likelihood of oxygen desaturation on induction of general anaesthesia. Pre-oxygenation with facemask is the commonest method method of pre-oxygenation.
- Conditions
- Apnea, Respiration; Arrest, Anesthesia
- Trial name
- PREOX (NCT04767867)
- Testing
- Pre-oxygenation
- Where
- Ireland
- Volunteers
- 84 people
- Sponsor
- University College Hospital Galway
Laryngoscopy, Apnea
High Flow Oxygen in Patients Undergoing Suspension Laryngoscopy Under General Anesthesia
Patients undergoing suspension laryngoscopy under general anaesthesia have oxygen delivered to their lungs through different methods. Inserting a tube in the trachea is the best means for oxygen delivery.
- Conditions
- Laryngoscopy, Apnea, Anesthesia
- Trial name
- OxALa (NCT03472118)
- Testing
- Nasal High Flow Oxygen
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- CMC Ambroise Paré