Clinical trials: High-risk Drinkers
High-risk Drinkers, Hazardous Alcohol Use
Evaluating a Digital Cognitive Behavioral Therapy for Hazardous Alcohol Use: A Pilot Study in South Korea
The goal of this single arm pilot study is to investigate the feasibility, acceptability and preliminary effectiveness of the mobile app SOBER; for reducing and preventing hazardous alcohol drinking.
- Trial name
- NCT06502756
- Testing
- SOBER, mobile Application providing digital CBT
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Yonsei University
Aging, Alcohol Drinking
The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers
The goal of this pilot study is to explore a combination of two interventions: (1) a behavioral alcohol-reduction intervention using motivational interviewing, and (2) a blinded probiotic microbiome or placebo intervention.
- Trial name
- NCT07415707
- Testing
- Visbiome, Motivational Interviewing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Alcohol Drinking, Binge Drinking
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
- Conditions
- Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence
- Trial name
- NCT05522075
- Testing
- Exercise Training, Alcohol Abstinence Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Alcohol Drinking, High-Risk Drinking Patterns
Clinical Effectiveness of a Motivational Interviewing-Based Conversational Mobile Application for High-Risk Drinkers
This study aims to evaluate and compare the degree of alcohol reduction between high-risk drinkers who use a motivational interviewing-based conversational agent (chatbot) application for four weeks and those in the control group…
- Trial name
- NCT07238998
- Testing
- Motivational Interviewing-Based Conversational Agent (Mobile Chatbot), No Intervention (Waitlist Control)
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Yonsei University
Alcoholism
Baclofen for the Treatment of Alcohol Drinkers
The main objective of this study is to show the effectiveness to a year of baclofen compared to placebo, on the proportion of patients with a low risk alcohol consumption or no, according to the WHO standards.
- Trial name
- BACLOVILLE (NCT01604330)
- Testing
- Baclofen
- Where
- France
- Volunteers
- 323 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infections
Project HERMITAGE: HIV Prevention in Hospitalized Russian Drinkers
The objective of this study is to test in a randomized controlled trial the effectiveness of a US secondary HIV prevention program to reduce HIV risk behaviors, STD acquisition, and alcohol consumption among HIV-infected Russians…
- Trial name
- NCT00483483
- Testing
- Individual and group HIV risk behavior counseling sessions, health education and support group
- Where
- 3 sites in Russia
- Volunteers
- 700 people
- Sponsor
- Boston Medical Center
Dehydration, Diabetes Mellitus, Type 2
INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers
Previous studies have indicated increased vasopressin due to hypertonic saline infusion impairs glucose regulation. The current study will examine the effect of low water intake on glucose regulation.
- Trial name
- INDIGO-2 (NCT04076995)
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pharynx Cancer, Larynx Cancer
Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population
Randomized multicenter trial to assess the impact of a screening program for heavy alcohol drinkers and smokers treated in alcohol addiction clinics on upper aerodigestive tract cancer mortality.
- Conditions
- Pharynx Cancer, Larynx Cancer, Oral Cavity Cancer, Oesophageal Cancer
- Trial name
- NCT00359645
- Testing
- Screening by head and neck clinical examination with a fiberoptic nasolaryngoscopy and an oesopharyngeal brush biopsy annually during 3 years
- Where
- 35 sites in France
- Volunteers
- 1,993 people, healthy volunteers welcome
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris