Clinical trials: Hip, open to volunteers
Postoperative Analgesia After Unilateral Hip Arthroplasty
Efficacy and Safety of TRD205 Tablets for Postoperative Analgesia in Unilateral Total Hip Arthroplasty (Phase IIb)
This is a phase IIa, multicenter ,randomized, double-blind, Double-Dummy, Active- and placebo-controlled study designed to evaluate the efficacy, safety and kinetic characteristics of TRD205 tablets for postoperative analgesia…
- Trial name
- TRD205 (NCT07543796)
- Testing
- TRD205 Tablets, oral; 400 mg initial dose, then 200 mg q12h for 3 doses; total 4 doses, TRD205 Tablets, oral; 800 mg initial dose, then 400 mg q12h; total 4 doses, TRD205 Tablets, oral; 1200 mg initial dose, then 600 mg q12h; total 4 doses
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Tide Pharmaceutical Co., Ltd
Hip Disease
ACE Acetabular Cup UK Multi-centre PMCF Study
A total hip replacement is one of the most successful and cost-effective surgical procedures in orthopaedics, and involves replacing both the hip ball and socket.
- Trial name
- NCT04123431
- Testing
- Total Hip Replacement
- Where
- United Kingdom
- Volunteers
- 225 people
- Sponsor
- JRI Orthopaedics
Arthropathy of Hip
Post-marketing Surveillance Study of the Saphir Stem in Primary Hip Surgery
Post-market clinical follow up investigation on the use of saphir stem and FIN Cup or Dualis system in the treatment of pathologies requiring hip arthroplasty.
- Trial name
- NCT05649007
- Testing
- hip arthroplasty with prosthesis
- Where
- France
- Volunteers
- 630 people
- Sponsor
- Gruppo Bioimpianti S.r.l.
Hip Disease
Everglade Stem, World Cup and World Liner Post Market Clinical Follow-up
The aim of the Study is to monitor the performance of the Signature Orthopaedics Everglade Stem, World Acetabular Cup and World Liner as a part of post-market vigilance and continuous improvement efforts.
- Trial name
- NCT06153940
- Testing
- Treatment
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Signature Orthopaedics
Fragility Fracture, Hip Fractures
RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures
A randomized controlled trial to evaluate AGN1 to prevent secondary hip fractures in osteoporotic women undergoing treatment of index hip fractures.
- Conditions
- Fragility Fracture, Hip Fractures, Osteoporosis
- Trial name
- NCT04796350
- Testing
- AGN1 LOEP treatment
- Where
- 66 sites in Austria, Belgium and 9 more
- Volunteers
- 2,400 people
- Sponsor
- AgNovos Healthcare, LLC
Hip Arthroplasty Replacement, Femoral Fractures
Cephalic Femoral Heads Follow Up
Study design: monocentric, retrospective, observational and post-market clinical study. Purpose: To demonstrate the safety and performance of cephalic femoral heads.
- Trial name
- NCT06873568
- Where
- Slovakia
- Volunteers
- 47 people
- Sponsor
- Limacorporate S.p.a
Hip Replacement
Spartan Stem, World Cup and World Liner Post Market Clinical Follow-up Study
The aim of the study is to monitor the performance of the Signature Orthopaedics Spartan Stem, World Acetabular Cup and World Liner as a post-market vigilance and continuous improvement efforts.
- Trial name
- NCT06172569
- Testing
- Spartan Stem, World Acetabular Cup and World Liner
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Signature Orthopaedics
Hip Arthritis, Hip Disease
MDR - PMCF Study for RingLoc Bipolar Acetabular Cup and Endo II Femoral Heads
The objective of this retrospective enrollment/prospective follow-up consecutive series PMCF study is to collect data confirming safety, performance, and clinical benefits of the RingLoc Bipolar Acetabular Cup and the Endo II…
- Conditions
- Hip Arthritis, Hip Disease, Hip Fractures, Hip Injuries
- Trial name
- NCT05199870
- Testing
- RingLoc Bipolar Acetabular Cup, Endo II Femoral Head
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Zimmer Biomet
Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Revision Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Revision Hip Prosthesis System in adult participants…
- Conditions
- Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint, Prostheses-related Infections, Joint Instability
- Trial name
- NCT07653295
- Testing
- Tıpmed™ Revision Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Hip Osteoarthritis, Rheumatoid Arthritis
G7 Dual Mobility With Vivacit-E or Longevity PMCF
This study is a global, multi-center, prospective, non-controlled, non-randomized, post-market clinical follow-up study. The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of…
- Conditions
- Hip Osteoarthritis, Rheumatoid Arthritis, Joint Diseases, Avascular Necrosis
- Trial name
- NCT05548972
- Testing
- G7 Dual Mobility with Vivacit-E bearing, G7 Dual Mobility Longevity bearing
- Where
- 10 sites in United States, Belgium and 2 more
- Volunteers
- 358 people
- Sponsor
- Zimmer Biomet
Hip Disease
ACE Acetabular Cup Spanish PMCF Study
A total hip replacement is one of the most successful and cost-effective surgical procedures in orthopaedics, involving the replacement of both the hip ball and socket.
- Trial name
- NCT07115732
- Testing
- Total Hip Replacement
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- JRI Orthopaedics
Total Hip Arthroplasty
Mpact 3D Metal Cup PMS
Cementless fixation, with or without screw augmentation, has evolved during the past few decades as the preferred method for acetabular reconstruction.
- Trial name
- NCT04801680
- Testing
- Mpact 3D metal cup
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Medacta International SA
Arthroplasty
Arthroplasty Cements Outcomes - A Post-market Follow-up
A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all Teknimed Arthroplasty range of products: CEMFIX® and GENTAFIX® bone cements families and CEMSTOP® cement restrictor, and all…
- Trial name
- NCT06354543
- Testing
- Cemented joint arthroplasty
- Where
- 10 sites in France, Italy
- Volunteers
- 1,050 people
- Sponsor
- Teknimed
Joint Diseases
Post Market Clinical Follow-Up Study for PROFEMUR® Preserve Classic Femoral Stem
Sponsor is conducting this post market clinical study to evaluate the safety and effectiveness of its PROFEMUR® Preserve Classic Femoral Stem.
- Trial name
- NCT04147559
- Testing
- Total Hip Arthroplasty Implant
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- MicroPort Orthopedics Inc.
Hip Fractures, Hip Hemiarthroplasty
Observational Study to Evaluate Long-Term Outcome in Hip Hemiarthroplasty
This PMCF study is designed to collect safety and efficacy data on hip hemiarthroplasty surgeries with Corin BiPolar-i shell and the Oceane+ or Meije Duo femoral stem up to 10 years.
- Conditions
- Hip Fractures, Hip Hemiarthroplasty, Osteoarthritis, Hip, Avascular Necrosis of Hip
- Trial name
- NCT05686278
- Testing
- Bipolar i and cemented stem (Océane+ or Meije)
- Where
- 4 sites in France
- Volunteers
- 368 people
- Sponsor
- Corin
Joint Osteoarthritis, Knee Osteoarthristis
Clinical Evaluation of TrHCROSS® for Different Joints
This post-market clinical investigation is designed to evaluate the safety and effectiveness of TrHCROSS®, a CE-marked cross-linked hyaluronic acid viscosupplement, in patients with mild to moderate osteoarthritis of the knee…
- Conditions
- Joint Osteoarthritis, Knee Osteoarthristis, Hip Ostearthritis, Shoulder Osteoarthritis
- Trial name
- NCT07870031
- Testing
- TrHCROSS®, Monovisc
- Volunteers
- 150 people
- Sponsor
- i+Med S.Coop.
Osteoarthritis
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the hip.
- Trial name
- NCT02844764
- Testing
- [StroMed + platelet rich plasma (PRP)]
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- VivaTech International, Inc.
Osteoarthritis of Hip
Hip Replacement System (HRS-P) in Primary Total Hip Arthroplasty
To evaluate effectiveness and safety of HHRS in subjects undergoing total hip arthroplasty (THA). Effectiveness will be evaluated using patient-reported, clinical, radiologic, and radiostereometric outcomes.
- Trial name
- (HRS-P) (NCT02836262)
- Testing
- HIT Hip Replacement System
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hip Innovation Technology
Osteoarthritis, Hip, Rheumatoid Arthritis
G7 Freedom Constrained Vivacit-E Liners
The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of the G7 Freedom Constrained Vivacit-E Acetabular Liners in primary and revision total hip arthroplasty.
- Conditions
- Osteoarthritis, Hip, Rheumatoid Arthritis, Non-Union Fracture, Trochanteric Fractures
- Trial name
- NCT05587244
- Testing
- Total Hip Arthroplasty with G7 Freedom Constrained Vivacit-E Liners
- Where
- 10 sites in United States
- Volunteers
- 202 people
- Sponsor
- Zimmer Biomet
Sarcopenia in Elderly, Frailty
Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures
This Phase II clinical study investigates the safety and effectiveness of a new drug, Isomyosamine, in patients with sarcopenia or frailty, conditions associated with aging and muscle weakness.
- Conditions
- Sarcopenia in Elderly, Frailty, Frailty/Sarcopenia, Frailty in Older Adults
- Trial name
- NCT06942182
- Testing
- Isomyosamine 250mg
- Volunteers
- 60 people
- Sponsor
- TNF Pharmaceuticals, Inc.