Clinical trials: Hip Arthritis
Arthritis of the Hip
Cemented Marathon/Corail Versus Pinnacle/Corail
A randomised, comparative, prospective, single-blinded trial of two hip prosthesis: 1. Marathon cemented all-poly acetabular cup(Depuy, Warsaw, Indiana), Corail uncemented femoral stem(Depuy, Warsaw, Indiana), 32mm Alumina Biolox…
- Trial name
- NCT01693627
- Testing
- Pinnacle/Corail with collar, Marathon/Corail with collar, Pinnacle/Corail without collar
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Haukeland University Hospital
Hip Osteoarthritis, Knee Osteoarthritis
Fit-Joints: Getting Fit for Hip or Knee Replacement
Osteoarthritis leads to reduced independence and quality of life. Total hip replacement is a successful and cost-effective surgical intervention to relieve pain and improve functioning in patients with osteoarthritis.
- Trial name
- Fit-Joints (NCT02885337)
- Testing
- Multi-Modal Frailty Intervention, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 41 people
- Sponsor
- McMaster University
Osteoarthritis, Hip, Osteo Arthritis Knee
Health Coaching for Patients Waiting for Hip or Knee Replacements
A randomised controlled feasibility study of a health coaching intervention targeting people on the waitlist for hip or knee replacement surgery with low patient activation.
- Trial name
- NCT06101875
- Testing
- Health Coach (Health coaching), Digital Toolkit (Control)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Sheffield Hallam University
Coxarthritis
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Capsular Resection Versus Capsular Flap Retention
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Capsular resection versus capsular flap retention. Prospective study design comparing clinical data in randomized THA patients who either had capsular resection or…
- Trial name
- NCT02970253
- Testing
- Capsular resection, Capsular retention
- Where
- Belgium
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- ZOL
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROFEMUR® Gladiator HA Coated Modular Femoral Stems
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) and resurfacing components marketed in the European Union (EU).
- Trial name
- NCT02314611
- Testing
- PROFEMUR® Gladiator HA Coated Modular Femoral Stem
- Where
- Belgium
- Volunteers
- 154 people
- Sponsor
- MicroPort Orthopedics Inc.
Coxarthrosis
Direct Anterior Approach Versus Direct Lateral Approach in Total Hip Arthroplasty
The purpose of this study is to compare the direct anterior approach and the direct lateral approach in primary total hip arthroplasty, regarding the postoperative function and pain, complications, radiological finds (X-ray)…
- Trial name
- DAAvsDLA (NCT02719236)
- Testing
- direct anterior approach, direct lateral approach
- Where
- Romania
- Volunteers
- 112 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Decision Making, Shared, Arthroplasty, Replacement, Knee
RCT Measuring the Effect of the ERVIN Software
The randomised clinical trial investigates the effect of using a clinical decision support system (CDSS) aiming to provide the patients and surgeons with greater transparency concerning the obtainable changes in function and…
- Conditions
- Decision Making, Shared, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip, Osteoarthritis, Knee
- Trial name
- NCT04332055
- Testing
- ERVIN
- Where
- Denmark
- Volunteers
- 223 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis of the Knee or Hip
Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip
The primary objective of the study is to describe the safety and tolerability of fasinumab, including adverse events of special interest (AESIs), in patients with pain due to radiographically-confirmed OA of the knee or hip.
- Trial name
- FACT LTS & OA (NCT02683239)
- Testing
- Fasinumab
- Where
- 149 sites in United States, Bulgaria and 19 more
- Volunteers
- 5,331 people
- Sponsor
- Regeneron Pharmaceuticals
Osteoarthritis (OA) of the Hip
TED Stocking vs. Reparel Garment After Hip Replacement
This randomized, prospective study compares the effectiveness of a novel bioactive garment (Reparel Leg Sleeve) versus standard TED compression stockings in reducing postoperative leg swelling, pain, and deep vein thrombosis…
- Trial name
- NCT07246200
- Testing
- Reparel Bioactive Sleeve, TED Stocking
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Reparel
Hip Arthrosis
Ceramic-on-Ceramic Total Hip Arthroplasty and Squeaking: Influence of Component Design
The investigators want to examine if specific acetabular liner designs can be a contributing factor to audible squeaking associated with CoC bearings.
- Trial name
- NCT01420900
- Testing
- THA with ABG II / Trident, THA with CLS / Trilogy
- Where
- Denmark
- Volunteers
- 204 people
- Sponsor
- Vejle Hospital
Osteoarthrosis
Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients
The study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total hip-arthroplasty (THA) surgery.
- Trial name
- NCT02445898
- Testing
- Methylprednisolone, Isotonic Sodium Chloride
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Hip
Minimal Opioid Use After Total Hip Replacement (THR)
Total hip arthroplasty can be associated with significant postoperative pain. Side effects of pain management may impair participation in physical therapy and slow readiness for discharge from the hospital.
- Trial name
- NCT03090152
- Testing
- Periarticular injection (Deep injection), Periarticular injection (Superficial injection), Bupivacaine
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis, Hip
Effects of Grade III Traction-mobilization in End-range Joint Position in Patients With Hip Osteoarthritis
Lower limb osteoarthritis is a major health problem in the westernized countries. The current gold standard treatment is joint replacement.
- Trial name
- NCT02469025
- Testing
- Manual caudal traction mobilization in resting position, Manual caudal traction mobilization in end range position, Selftreatment
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Zaragoza
Osteoarthritis
A Study to Assess Etoricoxib Versus Diclofenac in Chinese Patients With Osteoarthritis of the Knee or Hip (0663-080)(COMPLETED)
A Study to Assess Etoricoxib versus Diclofenac in Chinese Patients with Osteoarthritis of the Knee or Hip
- Trial name
- NCT00140972
- Testing
- MK0663; etoricoxib / Duration of Treatment:4 Weeks, Comparator: diclofenac sodium tablet 75 mg / Duration of Treatment:4 Weeks
- Volunteers
- 160 people
- Sponsor
- Organon and Co
Osteoarthritis, Chronic Pain
Preoperative Catastrophizing Predicts Pain Outcome After Shoulder, Knee and Hip Arthroplasty
Psychologic status is associated with poor outcome after joint arthroplasty and perhaps chronic pain. To enhance the therapeutic effect of a psychologic intervention, the specific disorders or pain-related beliefs that…
- Conditions
- Osteoarthritis, Chronic Pain, Catastrophization
- Trial name
- NCT02361359
- Testing
- Psychological questionnaires
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospital Ambroise Paré Paris
Arthritis
A Prospective Study to Evaluate the Effectiveness of a Haemostatic Agent in Primary Unilateral Total Hip Arthroplasty
This is a prospective, randomized, controlled, single-center study to assess the effectiveness of Vitagel, a surgical hemostat, in primary unilateral total hip arthroplasty (THA).
- Trial name
- NCT01285024
- Testing
- Vitagel
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- The Cleveland Clinic
Arthritis of the Hip
Polarstem Versus Corail; a Comparison of Micromotion and Periprosthetic Bone Remodelling of Two Femoral Stems
A randomised controlled trial comparing a recently introduced femoral stem with an established stem for total hip arthroplasty (THA). 60 patients will be randomised into one of the two groups 1.
- Trial name
- NCT05815953
- Testing
- Polarstem, Corail
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Helse-Bergen HF
Chronic Pain
A Double-blind Study of Controlled Release OROS Hydromorphone Compared to Placebo in Patients With Chronic Osteoarthritis (OA) Pain
To evaluate the efficacy of OROS Hydromorphone in reducing moderate to severe chronic pain in patients with Osteoarthritis (OA) Pain
- Trial name
- NCT00631319
- Testing
- OROS hydromorphone
- Volunteers
- 343 people
- Sponsor
- Mallinckrodt
Osteoarthritis
Improving Services and Outcomes for Joint Replacement Patients
Primary total knee or total hip replacement surgeries are costly high volume procedures \& outcomes may be affected by surgical \& care processes \& individual patient characteristics.
- Trial name
- NCT01899443
- Testing
- Observation
- Where
- 18 sites in Australia
- Volunteers
- 1,900 people
- Sponsor
- South West Sydney Local Health District
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROFEMUR® L Revision Femoral Stems
MicroPort Orthopedics (MPO) is conducting this PMCF study to evaluate the safety and efficacy of its THA and resurfacing components marketed in the EU.
- Trial name
- NCT02314702
- Testing
- PROFEMUR® L Revision Femoral Stem
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- MicroPort Orthopedics Inc.