Clinical trials: Hip Arthroplasty, Total
Pain Management, Arthroplasty Total Hip Replacement
QLESP Block Versus PENG+LFCN Block for Total Hip Arthroplasty
Total hip arthroplasty (THA) is a common surgery to replace damaged hip joints, but many patients experience significant pain after surgery, which can delay recovery and increase the need for strong pain medications (opioids).
- Trial name
- QLESP (NCT07771829)
- Testing
- QLESP Block, PENG+LFCN Block, ropivacaine
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Huazhong University of Science and Technology
Arthritis
SmartSet HV and Palacos R RSA Bone Cements in Primary Total Hip Arthroplasty
A randomised radiostereometric study comparing SmartSet HV and Palacos R acrylic bone cements.
- Trial name
- NCT00837850
- Testing
- Bone cement 1, Bone cement 2
- Volunteers
- 35 people
- Sponsor
- Norwegian University of Science and Technology
Total Hip Arthroplasty, Postoperative Pain
A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations
Peripheral nerve blocks are the standard of care for pain management after hip replacement surgery at UPMC Shadyside. This prospective, randomized study is intended to assess the effect of 0.1 versus 0.2% ropivacaine in lumbar…
- Trial name
- NCT01556724
- Testing
- 0.1% or 0.2% ropivacaine nerve blocks
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Sylvia Wilson
Hemorrhage Postoperative, Total Blood Loss
Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty
To find noninferiority relationship between oral and intravenous administration of tranexamic acid on peroperative and postoperative blood loss and serum concentration during primary total hip arthroplasty.
- Conditions
- Hemorrhage Postoperative, Total Blood Loss, Arthroplasty Complications
- Trial name
- NCT04691362
- Testing
- Tranexamic Acid Oral Product, Tranexamic acid injection
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- University of Liege
Arthritis Knee, Arthritis Hip
The Establishment of Total Joint Arthroplasty Registry Database
The purpose of this study will establish total joint arthroplasty registry database in Kaohsiung Chang Gung Memorial Hospital and collect patient-reported outcome.
- Trial name
- NCT04479462
- Testing
- total joint arthroplasty
- Where
- Taiwan
- Volunteers
- 6,000 people
- Sponsor
- Chang Gung Memorial Hospital
Arthritis Knee, Arthritis Hip
Developing an Opioid Taper Intervention Before Total Joint Arthroplasty
The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery.
- Conditions
- Arthritis Knee, Arthritis Hip, Chronic Pain
- Trial name
- NCT05788016
- Testing
- opioid taper
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Alabama at Birmingham
Total Hip Replacement, Arthroplasty
Pain After Preoperative UltraSound Guided Hip Injections for Total Hip Arthroplasty (PUSH)
The purpose of the study is to assess the accuracy of Butterfly IQ ultrasound for intra-articular hip injections, and to see if an injection given intra-articular before incision provides any benefit in preemptive pain relief or…
- Trial name
- PUSH (NCT04219098)
- Testing
- Butterfly IQ, Standard of Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Anne Arundel Health System Research Institute
Prosthesis-Related Infections
Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty
The primary purpose of this study is to compare the re-infection rates in patients undergoing 2-stage revision arthroplasty who receive additional oral antibiotic therapy to those patients who received in-hospital perioperative…
- Trial name
- NCT01760863
- Testing
- Oral Antibiotics
- Where
- 4 sites in United States
- Volunteers
- 185 people
- Sponsor
- Rush University Medical Center
Hip Arthroplasty Replacement
Comparison of Wear Between Two Dual-mobility Acetabular Cups in Patients Undergoing Total Hip Arthroplasty
In 2022, data from the UK's National Joint Registry (NJR) and the American Joint Replacement Registry (AJRR) indicated that Total Hip Replacement (THR) is the most commonly performed orthopaedic joint surgery.
- Trial name
- CUPUSURE (NCT07207005)
- Testing
- ECIMA CORIN, CORIN
- Where
- France
- Volunteers
- 96 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Osteoarthritis, Avascular Necrosis
A Clinical Evaluation of Metal Ion Release From Metal-on-Metal Cementless Total Hip Arthroplasty
A clinical Evaluation to determine metal ion release from 4th generation metal-on-metal hip articulating surfaces in cementless total hip arthroplasty.
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT00757354
- Testing
- Metal on Metal cementless hip
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Zimmer Biomet
Regional Anesthesia
Perioperative Analgesia for Total Hip Arthroplasty
This study is comparing the effect of lumbar plexus block and fascia iliaca block with general anesthesia to provide perioperative pain control and compare their effects on hemodynamics
- Trial name
- NCT04670497
- Testing
- bupivacaine 0.5% with 1:200000 adrenaline
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Regional Anesthesia, Hip Arthroplasty
SFIB vs PENG Block in the Anesthesia for Total Hip Replacement
Total hip replacement is one of the most common orthopedic operations. According to statistical studies, more than 1 million of such surgical interventions are performed annually in the world.
- Trial name
- NCT07061223
- Testing
- SFIB, PENG block, Patient control analgesia
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
LOS, Postoperative Pain
Effects of Methylprednisolone After Total Hip Arthroplasty
The purpose of the study is to compare the effects of pre-operative methylprednisolone (125mg iv) versus placebo on postoperative outcome after hip arthroplasty.
- Conditions
- LOS, Postoperative Pain, Postoperative Nausea and Vomiting, Sleeping Quality
- Trial name
- NCT00968903
- Testing
- Methylprednisolone
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Coxarthrosis
EO Footprint as a Landmark During DAA THA
One of the goals of Total Hip Arthroplasty (THA) is to reconstruct leg length as adequately as possible. In order to achieve this one needs landmarks that are visible both on the templating X ray as well as during surgery.
- Trial name
- NCT04623073
- Testing
- Total Hip arthroplasty via a Direct Anterior Approach
- Where
- Belgium
- Volunteers
- 135 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Analgesia
Lumbar Erector Spinae Plane Block and Fascia Iliaca Compartment Block After Total Hip Arthroplasty
Compare the analgesic efficacy of ultrasound-guided lumbar erector spinae plane block (L-ESPB) versus fascia iliaca compartment block (FICB) in patients scheduled for total hip arthroplasty.
- Trial name
- NCT05905510
- Testing
- Lumbar Erector spinae plane block (L-ESPB), Fascia iliaca compartment block (FICB), spinal anesthesia plane block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Osteoarthritis of the Hip, Degenerative Joint Disease of Hip
Evaluate the Safety and Effectiveness of the Polymotion Hip Resurfacing (PHR) System Compared to Total Hip Arthroplasty
The goal of this clinical trial is to evaluate the safety and effectiveness of the Polymotion Hip Resurfacing (PHR) System compared to total hip arthroplasty, for adults who require hip resurfacing arthroplasty due to 1)…
- Conditions
- Osteoarthritis of the Hip, Degenerative Joint Disease of Hip, Dysplasia; Hip
- Trial name
- PHR (NCT06792539)
- Testing
- Polymotion Hip Resurfacing (PHR) System
- Where
- 9 sites in United States, Bermuda
- Volunteers
- 238 people
- Sponsor
- JointMedica Inc.
Primary Total Hip Arthroplasty
Opioid Free Anesthesia in Total Hip Arthroplasty
Total hip arthroplasty (THA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- OFATHA (NCT05072704)
- Testing
- Sufentanil, Dexmedetomidine
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CMC Ambroise Paré
Pain, Postoperative, Opioid Use
IV vs. Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty
The purpose of this study is to determine how well two different methods of administrating Tylenol reduce pain and improve patient satisfaction after total hip replacement (THR) surgery.
- Trial name
- IV Tylenol (NCT03020966)
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Hospital for Special Surgery, New York
Total Hip Arthroplasty
Anterior Capsulectomy vs. Repair in Direct Anterior THA
Randomized prospective study comparing the anterior capsule repair vs capsulectomy with regards to post-operative pain and range of motion outcomes in elective primary unilateral direct anterior approach THA for osteoarthritis.
- Trial name
- NCT01621932
- Testing
- Direct anterior approach with capsulectomy, Direct anterior approach without capsulectomy
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Osteoarthritis, Avascular Necrosis
A Clinical Investigation of ArComXL® Polyethylene in Total Hip Replacement
The purpose of this data collection is to determine long term survival rate of ArComXL® highly cross-linked polyethylene
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- NCT00698152
- Where
- 5 sites in United States
- Volunteers
- 149 people
- Sponsor
- Zimmer Biomet
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