Clinical trials: Hip Arthroplasty Replacement
Arthroplasty, Replacement, Hip
Functional Movement Retraining After Hip Replacement
Total hip arthroplasty (THA) is a common surgical procedure among Veterans. It is most often used to treat hip osteoarthritis, which is more common among Veterans than the general population.
- Trial name
- FMR-THA (NCT01878175)
- Testing
- Functional Movement Retraining
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Postoperative Recovery
A Study to Evaluate the Effect of GRF6021 on Postoperative Recovery Following Primary Hip or Knee Arthroplasty
This study will evaluate the safety, tolerability and effect of GRF6021 on clinical recovery parameters in participants undergoing primary hip or knee arthroplasty.
- Trial name
- NCT03981419
- Testing
- GRF6021
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Alkahest, Inc.
Arthroplasty, Replacement, Hip
ABC/Trident® Ceramic Post Approval Study
The purpose of the Post Approval Study of the ABC and Trident® systems is to continue to demonstrate the safety and efficacy of the alumina-on-alumina bearing surfaces combined with the appropriate shell in a cementless…
- Trial name
- NCT00960206
- Testing
- Trident® Ceramic Insert/Trident® AD HA Acetabular Shell, Alumina Insert/PSL® Microstructured Acetabular Shell or Secur-Fit® HA PSL® Acetabular Shell, OmniFit® Series II Insert/OmniFit® PSL® Microstructured Acetabular Shell
- Where
- 6 sites in United States
- Volunteers
- 413 people
- Sponsor
- Stryker Orthopaedics
Arthroplasty, Replacement, Hip, Blood Transfusion
Comparison in Need for Bank Blood Between Patients Undergoing Total Hip Surgery That Either Receive Their Own Blood Back or Not
The study is a prospective, controlled, randomised and assessor blind study that investigate if the need for bank blood transfusion could be reduced in patients, undergoing primary or revision total hip replacement surgery, who…
- Conditions
- Arthroplasty, Replacement, Hip, Blood Transfusion, Blood Transfusion, Autologous
- Trial name
- NCT00822588
- Testing
- Sangvia® System
- Where
- 6 sites in Austria, Netherlands and 2 more
- Volunteers
- 227 people
- Sponsor
- Wellspect HealthCare
Arthroplasty, Replacement, Prevention of Venous Thromboembolism
Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate
To supplement the current evidence of the effect of Pradaxa® (dabigatran etexilate) on coagulation parameters, including a calibrated thrombin time test, in patients with moderate renal impairment undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Prevention of Venous Thromboembolism, Moderate Renal Impairment (CrCl 30-50 mL/Min)
- Trial name
- NCT01184989
- Testing
- Dabigatran etexilate
- Where
- 10 sites in Austria, Canada and 4 more
- Volunteers
- 142 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis, Hip
Systemic Steroids for Peripheral Nerve Blocks
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
- Trial name
- NCT02464176
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Total Hip Arthroplasty
A Clinical Trial of a Metal on Poly Component Versus CORAIL Stem: A Bone Mineral Density Study
The main goal is to prospectively evaluate bone mineral density adjacent to the femoral component and femoral bone remodeling of two different designs: CORAIL impaction broach titanium stem compared to a modular titanium femoral…
- Trial name
- NCT01558752
- Testing
- Total hip replacement with titanium shell and CORAIL stem, Total hip replacement with Modular Titanium Femoral Stem
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Ottawa Hospital Research Institute
Total Knee Replacement, Total Hip Replacement
Meloxicam for Pain Management After Total Joint Arthroplasty (TJA)
The purpose of this project is to determine if a change in patient reported pain, nausea and vomiting after total knee and hip arthroplasty could be observed with the substitution of Intravenous meloxicam for ketorolac in the…
- Trial name
- NCT05291598
- Testing
- IV meloxicam, Ketorolac
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Miami
Hip Osteoarthritis, Knee Osteoarthritis
Comparative Effectiveness of Decision Support Strategies for Joint Replacement Surgery
This study is a 2X2 factorial randomized trial that will the examine the comparative effectiveness of two patient decision aids for hip and knee osteoarthritis (OA) as well as the impact of a surgeon-focused intervention.
- Trial name
- NCT02729831
- Testing
- Interactive decision aid, Video decision aid, Provider Report
- Where
- 3 sites in United States
- Volunteers
- 1,220 people
- Sponsor
- Massachusetts General Hospital
Osteoarthritis of Hip, Regional Anesthesia
Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement
The purpose of this research study is to evaluate the analgesic efficacy of adding a single shot parasacral (sciatic) nerve block to a continuous lumbar plexus block in patients undergoing total hip replacement.
- Conditions
- Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty
- Trial name
- NCT02161484
- Testing
- Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rita Merman
Hip Fracture, Osteoarthritis
Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery
The purpose of this study is to determine the effects of two postoperative interventions designed to preserve muscle protein after major hip or knee surgery.
- Conditions
- Hip Fracture, Osteoarthritis, Femur Head Necrosis
- Trial name
- NCT00393848
- Testing
- Essential amino acid supplement, Ketoconazole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arkansas
Arthroplasty, Replacement, Hip
Trident® Tritanium™ Acetabular Shell Revision Study
The purpose of this study is to evaluate a hip implant system used when a previous hip replacement surgery has failed.
- Trial name
- NCT00535626
- Testing
- Trident® Tritanium™ Acetabular Shell
- Where
- 15 sites in United States
- Volunteers
- 241 people
- Sponsor
- Stryker Orthopaedics
Total Hip Arthroplasty
Spinal Anesthesia in Total Hip Arthroplasty
Spinal anesthesia is commonly used in patients undergoing total hip replacements. The purpose of this study is to compare lidocaine to bupivacaine spinal anesthesia in patients having a total hip arthroplasty (THA).
- Trial name
- NCT02818894
- Testing
- Lidocaine, Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- Thomas L Bradbury
Osteoarthritis, Knee, Osteoarthritis, Hip
Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total joint arthroplasty, as compared to standard of care analgesia.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
- Trial name
- NCT02197273
- Testing
- Liposomal bupivacaine, Standard of care analgesia
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- OhioHealth
Osteoarthritis, Knee, Osteoarthritis, Hip
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a…
- Trial name
- NCT03737149
- Testing
- mymobility with Apple Watch
- Where
- 30 sites in United States, Australia and 2 more
- Volunteers
- 6,559 people
- Sponsor
- Zimmer Biomet
Venous Thromboembolism, Bleeding
Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)
Several human genes affect how medications are metabolized by the body. It is believed that knowledge of variations of these genes can help health care providers better manage an anticoagulation medicine called warfarin…
- Trial name
- NCT00634907
- Testing
- Pharmacogenetic-based warfarin dosing, Usual care warfarin dosing
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Gwen McMillin
Hip Osteoarthritis
Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement
The Lumbar Plexus (LP) block is currently used as the standard-of-care regional anesthesia technique to provide postoperative pain management after primary hip replacement surgery at UPMC Shadyside Hospital.
- Trial name
- NCT03801265
- Testing
- Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Sharad Khetarpal
Hip Arthroplasty
Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement
Chronic pain in patients following total hip replacement seems to be a significant problem. Previous research has shown that more effective pain management in the early postoperative period may decrease the incidence of the…
- Trial name
- NCT00621530
- Testing
- ketorolac tromethamine opthalmic solution
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Wake Forest University
Arthroplasty, Replacement, Hip
ATX Register Accolade Stem & Trident/Tritanium Cup With X3 Insert
The aim of this register is to determine the Accolade/Accolade II stem and Trident/Tritanium cup survivorship over years.
- Trial name
- ATX (NCT02520544)
- Testing
- Accolade stem, Accolade II stem, Trident/Tritanium cup
- Where
- 8 sites in Belgium, Netherlands and 2 more
- Volunteers
- 472 people
- Sponsor
- Stryker Orthopaedics
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Improvement of Patient Satisfaction and Clinical Outcomes Using JointCOACH
JointCOACH is a web-based communication platform that enables joint replacement patients to communicate with their care team via computer or smartphone throughout their episode of care, from the time that surgery is scheduled…
- Trial name
- NCT03499028
- Testing
- JointCOACH
- Where
- United States
- Volunteers
- 446 people
- Sponsor
- The Cleveland Clinic