Clinical trials: Hip Infection
Surgery, Cataract
Routine Surgical Procedures During COVID-19 Pandemic: a French Nationwide Cohort Study
Determine the consequences of COVID-19 pandemic on routine targeted surgeries. Five surgical procedures were considered : cataract surgery, hip and knee arthoplasties, coronary revascularisation by angioplasty and definitive…
- Conditions
- Surgery, Cataract, Hip Arthroplasty, Knee Arthroplasty
- Trial name
- NCT05197660
- Testing
- surgical procedures
- Where
- France
- Volunteers
- 2,000,000 people
- Sponsor
- EPI-PHARE
Hip Prosthesis Infection
Prosthetic Hip Infections: Prospective Study
Data from large prospective cohort studies of prosthetic joint infections are lacking. Aim of this study: analyzing prospectively the incidence of reinfection in patients with prosthetic hip infections who underwent surgery and…
- Trial name
- PHIPS (NCT01963520)
- Where
- France
- Volunteers
- 347 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Prosthetic Joint Infection
Bacteriophage Therapy in Patients With Prosthetic Joint Infections
This is a study designed to evaluate bacteriophage therapy in patients with chronic prosthetic joint infections.
- Trial name
- NCT04787250
- Testing
- Phage Therapy, Two-Stage Exchange Arthroplasty
- Where
- United States
- Sponsor
- Adaptive Phage Therapeutics, Inc.
Hip Prosthetic Joint Infection, Knee Prosthetic Joint Infection
Short Interval in Treatment of PJI
Patients with hip, knee and shoulder PJI, will be treated with a two-stage exchange Revision. Patients will be randomized into 2 groups: the experimental Group will get a reimplantation after a short interval (2-3 weeks) while…
- Conditions
- Hip Prosthetic Joint Infection, Knee Prosthetic Joint Infection, Shoulder Prosthetic Joint Infection
- Trial name
- Fast-track (NCT02372435)
- Testing
- Shortening of the interval of two-stage prosthesis exchange
- Volunteers
- 418 people
- Sponsor
- Charite University, Berlin, Germany
Staphylococcal Infections, Methicillin-resistant Staphylococcus Aureus
Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty
This study will evaluate the safety and effectiveness of daptomycin, an antibiotic compared to another one which is vancomycin when given around the time of joint replacement surgery.
- Trial name
- NCT01196169
- Testing
- Daptomycin, Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Mountain Home Research & Education Corporation
Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
ROADMAP Clinical Trial
Artificial joint infections are treated with different types of antibiotics and surgery. The ROADMAP study aims to find out which treatments currently used work best in regards to surgery, antibiotic choice as well as the time…
- Conditions
- Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Large Joint Prosthetic Joint Infections
- Trial name
- ROADMAP (NCT06771050)
- Testing
- Debridement and Implant Retention (DAIR), Antibiotic Choice, Antibiotic duration Part A - Single stage revision
- Where
- 43 sites in Australia, New Zealand
- Volunteers
- 2,500 people
- Sponsor
- University of Newcastle, Australia
Prosthesis-Related Infections, Hip Prosthesis Infection
Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy.
It is not known in the literature how much sonication affects the patient's treatment. Another important issue is that the place of this method in diagnosis is not clear.
- Conditions
- Prosthesis-Related Infections, Hip Prosthesis Infection, Joint Infection, Biofilm
- Trial name
- NCT04304885
- Testing
- Sonication method
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Prosthetic Joint Infection
Cost Of Failure Following Reimplantation After a 2-Stage Exchange Strategy For Hip Or Knee Prosthetic Joint Infection
This study concerns patients having had an infection on their prosthesis (hip, knee,..) and for whom a 2-step exchange of prosthesis has been done.
- Trial name
- NCT03612076
- Testing
- Global cost of management of PJI
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Hospices Civils de Lyon
Hip Fractures, COVID-19
Anesthesia Technique in COVID-19 Positive Hip Fracture Patients
Patients with COVID undergoing hip fracture repair have high mortality rates. If spinal anesthesia is associated with decreased rates of mortality, this study could provide hypothesis generating data for prospective studies.
- Conditions
- Hip Fractures, COVID-19, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT05133648
- Testing
- Hip Fracture Surgery, COVID-19 infection
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Femoral Neck Fractures, Prosthetic Infection
Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture
Rational for conducting the study: Periprosthetic joint infection (PJI) is the most feared complication following prosthetic replacement of the hip joint and is associated with increased mortality, morbidity and economic burden.
- Trial name
- DAICY (NCT05164081)
- Testing
- antibiotic loaded bone cement (gentamicin+clindamycin) COPAL G+C (Heraeus)., antibiotic loaded bone cement (gentamicin) Paladins R+G (Heraeus) or Refobacin (Biomet).
- Where
- Sweden
- Volunteers
- 7,000 people
- Sponsor
- Umeå University
Prosthesis-Related Infections
Dosing of Antibiotics During Reimplantation of Infected Knee and Hip Prostheses
The purpose of the study is to evaluate the concentrations of antibiotics used as empirical treatment in serum and periprosthetic tissues during reimplantation of infected hip and knee prostheses
- Trial name
- DOSOS (NCT02860767)
- Where
- 5 sites in France
- Volunteers
- 30 people
- Sponsor
- Tourcoing Hospital
Bone Infection, Osteomyelitis
Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections
Because of its prolonged terminal half-life, dalbavancin is an extremely attractive option in treating Gram-positive infections caused by S. aureus including MRSA, and streptococcal species.
- Conditions
- Bone Infection, Osteomyelitis, Septic Arthritis, Joint Infection
- Trial name
- NCT03426761
- Testing
- Dalbavancin, Vancomycin
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Infectious Diseases Physicians, Inc.
Osteomyelitis
Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci
This is a research study designed to look at the efficacy and safety of daptomycin given at a dose of 6 mg/kg or 8 mg/kg in subjects being treated for prosthetic hip or knee infections caused by Staphylococci.
- Trial name
- NCT00428844
- Testing
- daptomycin, vancomycin, teicoplanin
- Where
- 26 sites in United States, Russia and 1 more
- Volunteers
- 75 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Antibiotic Prophylaxis in Primary Joint Arthroplasty of the Hip and Knee.
A retrospective study will be performed to compare the incidence of revision procedures performed for the treatment of postoperative periprosthetic joint infection (PJI) between patients treated with a single preoperative…
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Antibiotic Prophylaxis
- Trial name
- NCT03348254
- Testing
- Single shot antibiotic prophylaxis, Multiple shot antibiotic prophylaxis
- Where
- Netherlands
- Volunteers
- 242,179 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Revision Total Hip Arthroplasty, Revision Total Knee Arthroplasty
Tissue Culture Versus Swab Culture in Prosthetic Joint Infections
The main purpose of this study is to compare the effectiveness and accuracy of tissue cultures and swab cultures to diagnose prosthetic joint infection.
- Trial name
- NCT01482533
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Infections Joint Prosthetic
Egyptian Arthroplasty Surgeons' Antibiotics Usage Awareness
Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are procedures successfully applied to manage various end-stage chronic hip and knee diseases, such as osteoarthritis, rheumatoid arthritis, and femoral head…
- Trial name
- NCT06451224
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- South Valley University
Periprosthetic Joint Infection (PJI), Periprosthetic Knee Infection
Analysis of the Etiopathogenesis of Postoperative Complications in Orthopedic Patients Using Knee and Hip Arthroplasty as an Example
Relevance and Rationale Due to the widespread development of high-tech medical care in traumatology and orthopedics for patients with severe forms of hip and knee osteoarthritis and aseptic necrosis, and the increasing number of…
- Conditions
- Periprosthetic Joint Infection (PJI), Periprosthetic Knee Infection, Periprosthetic Hip Infection, Diagnostic
- Trial name
- NCT07813832
- Where
- Russia
- Volunteers
- 750 people
- Sponsor
- People's Friendship University of Russia
Surgery, Knee Arthropathy
Evaluation of Arthroplasty Treatment
The aim of the study is to examine patients after knee and hip endoprosthesis in the longitudinal section and to evaluate the surgical outcome.
- Conditions
- Surgery, Knee Arthropathy, Hip Arthropathy, Prosthetic-joint Infection
- Trial name
- Endo-GEP (NCT07799818)
- Testing
- Joint replacement
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bonn
Total Knee Arthroplasty, Total Hip Arthroplasty Revision
Interventional Study Exploring the Occurrence of Surgical Site Infections.
Interventional study exploring surgical site complication occurrences in high-risk revision patients undergoing TKA or THA using NPWT.
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
- Trial name
- NCT06661473
- Testing
- Avance Solo Negative Pressure Wound Therapy
- Where
- 8 sites in United States
- Volunteers
- 104 people
- Sponsor
- Molnlycke Health Care AB
Hip Arthroplasty Replacement
Follow up Study of Patients Undergoing Total Hip Arthroplasty CERAFIT® Grafted With Poly Sodium Styrene Sulfonate
The risk of infection after primary Total Hip Arthroplasties (THA)is generally estimated to be less than 1% but remains a severe and costly complication, source of morbidity and even mortality.
- Trial name
- NCT01454271
- Testing
- Total Hip Arthroplasty Replacement
- Where
- France
- Sponsor
- Societe ACTIVBIOMAT