Clinical trials: Hip Infection
Joint Prosthesis; Complications
Joint Aspiration in Dysfunctional Hip, Knee or Shoulder Prostheses
After a hip, knee or shoulder arthroplasty, the evolution is not always favorable. It can be marked by an infectious or non-infectious complication, most often implant failure.
- Trial name
- JAD-Pro (NCT06054711)
- Testing
- joint puncture
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Hip Surgery
Preoperative Intravenous Omega 3 Fatty Acids Administration in Elderly Patients Undergoing Hip Surgery
The perioperative administration of n-3 fatty acids has been shown to lead to favorable effects on outcome in patients with severe surgical interventions by lowering the magnitude of inflammatory response and by modulating the…
- Trial name
- NCT00890123
- Testing
- Omegaven-IV FO
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Nizam's Institute of Medical Sciences University, India
Hip Prosthesis Infection
Early Discrimination of Periprosthetic Hip Infections Using Neural Networks (SEPTIC-ANNR)
The study is about the role of cellular neural networks-genetic algorithm in the diagnosis of periprosthetic hip infections. A retrospective case series of septic and aseptic loosening of primary hip arthroplasties is selected.
- Trial name
- SEPTIC-ANNR (NCT04119804)
- Testing
- cellular neural networks-genetic algorithm
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Istituto Ortopedico Rizzoli
Hip Osteoarthritis, Hip Prosthesis Infection
Image Quality of EOSedge for Radiographic Evaluation of Hip Implant
EOSedge is a precise, low dose imaging system that delivers full body, high-quality images covering the full set of musculoskeletal and orthopedic exams.
- Trial name
- PreHIPEOS (NCT05615701)
- Testing
- EOSedge imaging
- Where
- France
- Volunteers
- 97 people
- Sponsor
- University Hospital, Montpellier
Hip Prosthesis Infection, Knee Prosthesis Infection
Proof of Concept Study to Assess Safety and Efficacy of Phage Therapy in Hip or Knee Prosthetic Joint Infections Due to Staphylococcus Aureus Treated by DAIR.
Total joint replacements are effective for chronic pain but can lead to Prosthetic Joint Infections (PJI), primarily caused by Staphylococcus aureus and resistant to antibiotics.
- Trial name
- GLORIA (NCT06605651)
- Testing
- Anti-Staphylococcus aureus Bacteriophages (PP1493 and PP1815) intra-articular injection with 0.9% NaCl solution, 0.9% NaCl solution
- Volunteers
- 100 people
- Sponsor
- Phagenix
Femoral Neck Fracture, Infection
Early Periprosthetic Joint Infection and Outcome Debridement, Antibiotics and Implant Retention
Introduction Periprosthetic joint infection (PJI) is a severe complication to hip arthroplasty for femoral neck fractures (FNF).
- Trial name
- DAIR (NCT02771639)
- Testing
- Hip arthroplasty
- Volunteers
- 736 people
- Sponsor
- Sundsvall Hospital
Bursa; Tuberculous, Hip Bursitis
Trochanteric Bursal Repair After a Total Hip Replacement - Are There Benefits During the First 90 Days
During total hip arthroplasty surgery, the trochanteric bursa is routinely excised. This anatomical structure, which functions as a soft tissue barrier, is generally recommended for removal as it facilitates the surgical…
- Conditions
- Bursa; Tuberculous, Hip Bursitis, Deep Gluteal Syndrome, Hip Disease
- Trial name
- NCT06553508
- Testing
- Trochanteric bursa repaired, Trochanteric bursa unrepaired
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Ankara City Hospital Bilkent
Periprosthetic Infection Total Hip Arthoplasty
Treatment of Acute Periprosthetic Total Hip Arthroplasty Infections
The purpose of this study is to determine the success rate of two treatments for infection after total hip replacement: single stage arthroplasty exchange (your surgeon will take out your original implants and replace them with a…
- Trial name
- NCT01712880
- Testing
- open debridement with modular exchange, one stage exchange
- Where
- United States
- Sponsor
- OrthoCarolina Research Institute, Inc.
Total Hip Replacement, Arthroplasty Complications
REVISITS: Revision Single or Two Stage Surgery
Hip replacement surgery is common, with over 60,000 cases in Canada annually. After hip replacement, about 1-2% patients develop a deep infection in their artificial hip implant, called a periprosthetic joint infection (PJI).
- Trial name
- REVISITS (NCT03741296)
- Testing
- Single stage revision, Two-stage revision
- Volunteers
- 110 people
- Sponsor
- Unity Health Toronto
Infection
Intra-articular Vancomycin Powder in Knee and Hip Arthroplasty
The purpose of this study is to compare infection rates when patients, elected for primary or aseptic revision THA / TKA, have a single intravenous antibiotic dose versus one single intravenous antibiotic dose in combination with…
- Trial name
- NCT04399642
- Testing
- Arthroplasty
- Where
- Canada
- Volunteers
- 1,832 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Total Hip and Knee Arthroplasties
Teicoplanin Prophylaxis for Total Hip or Knee Arthroplasty
This is a prospective, open-label, randomized clinical trial where patients were administered prophylaxis for total hip or knee arthroplasty either with teicoplanin or with other antibiotics.
- Trial name
- NCT00719056
- Testing
- Teicoplanin, β-lactams or ciprofloxacin
- Where
- 3 sites in Greece
- Volunteers
- 616 people
- Sponsor
- University of Athens
Complications; Arthroplasty, Infection or Inflammation, Wound Complication
Improvement in Wound Healing With Negative Pressure Wound Therapy for Postoperative Total Hip Arthroplasty
For the target population of adult patients following primary total hip arthroplasty, the randomized clinical trial will be used to evaluate the efficacy of the use of a mobile negative pressure wound therapy(NPWT) device…
- Trial name
- NCT02355691
- Testing
- PREVENA
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Prosthesis-related Infections, Staphylococcal Infections
Rifampin Combination Therapy Versus Monotherapy in Early Staphylococcal Infections After Total Hip and Knee Arthroplasty
The number of patients requiring joint replacement is increasing due to its success in restoring function and pain relief, and the growing population of the elderly.
- Trial name
- NCT00423982
- Testing
- Rifampin-combination therapy, Monotherapy
- Where
- 8 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Staphylococcal Infections
StaphVAX Immunogenicity and Safety in Orthopaedic Joint Surgery
Staphylococcus aureus (S. aureus) is the most common pathogen encountered in infections associated with orthopedic surgery. StaphVAX® is a bivalent S.
- Trial name
- NCT00211965
- Testing
- S. aureus Types 5 and 8 Capsular Polysaccharide Conjugate
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Nabi Biopharmaceuticals
Hip Effusion, Septic Arthritis
Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
The purpose of this study is to determine if pediatric emergency medicine providers can accurately diagnose a hip effusion using point-of-care ultrasound (POCUS) compared to radiology ultrasound (RADUS).
- Conditions
- Hip Effusion, Septic Arthritis, Transient Synovitis, Hip
- Trial name
- NCT05971745
- Where
- 6 sites in United States, Australia
- Volunteers
- 161 people
- Sponsor
- Connecticut Children's Medical Center
HIV Infections, Lipodystrophy
Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities
The purpose of this study is to see whether metformin alone, rosiglitazone alone, or metformin and rosiglitazone together will lower insulin levels in the blood and decrease fat in the abdomen or other parts of the body.
- Conditions
- HIV Infections, Lipodystrophy, Hyperinsulinemia
- Trial name
- NCT00015691
- Testing
- Metformin hydrochloride, Rosiglitazone maleate
- Where
- 34 sites in United States
- Volunteers
- 105 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infection of Total Hip Joint Prosthesis, Infection of Total Knee Joint Prosthesis
Phage Therapy in Prosthetic Joint Infection Due to Staphylococcus Aureus Treated With DAIR.
Pilot non comparative study assessing the clinical control of infection of DAIR + SAT +NaCl and DAIR + SAT + Phages anti-Staphylococcus aureus in patients with Staphylococcus aureus Prosthetic Joint Infection with an indication…
- Trial name
- PhagoDAIRI (NCT05369104)
- Testing
- Anti-Staphylococcus aureus Bacteriophages
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Phagenix
Osteoarthritis, Infection
Prospective, Randomized Study Evaluating The Efficacy of Chlorhexidine Gluconate Impregnated No-Rinse Cloths.
Subjects in the study were randomized to a treatment group using Chlorhexidine cloths or a standard-of-care group who only had a bath with antibacterial soap and water.
- Trial name
- SAGE (NCT02469311)
- Testing
- chlorhexidine impregnated cloths, Standard of care bathing with antibacterial soap and water
- Volunteers
- 539 people
- Sponsor
- LifeBridge Health
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Preoperative Fasting and the Gut Microbiome Before Hip Replacement
Postoperative complications occur in 5-15% of patients undergoing elective primary total hip arthroplasty (THA), including periprosthetic joint infection (PJI), thrombosis, wound healing disorders, and metabolic dysregulation.
- Conditions
- Hip Osteoarthritis, Arthroplasty, Replacement, Hip, Postoperative Complications, Surgical Wound Infection
- Trial name
- PreFAST-Hip (NCT07651462)
- Testing
- Buchinger Fastenbox + intermittent fasting (20-day preoperative schedule)
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Charite University, Berlin, Germany
Hip Infection
Efficacy of New Silver-coated Prosthesis in Reducing the Incidence of Periprosthetic Infections
The aim of the present clinical study, of prospective observational nature with biological study, is to conduct a clinical investigation on the the efficacy of a device coated with bacteriostatic silver coating, with the overall…
- Trial name
- NCT06887816
- Testing
- silver coated device, not silver coated device
- Where
- 2 sites in Italy
- Volunteers
- 70 people
- Sponsor
- Istituto Ortopedico Rizzoli