Clinical trials: Hip Joint Disorders
Osteoarthritis, Hip
Whole Blood Metal Ion Concentrations in Metal-on-metal Total Hip Arthroplasty and Hip Resurfacing
The investigators aimed to investigate the possible differences in metal ion concentrations in patients following one of two types of metal-on-metal articulating hip prosthesis regarding chromium and cobalt concentration…
- Trial name
- NCT04585022
- Testing
- Magnum, Zimmer Biomet, Warsaw, IN, Recap, Zimmer Biomet, Warsaw, IN
- Volunteers
- 75 people
- Sponsor
- Hvidovre University Hospital
Degenerative Joint Disease of Hip
Post-Approval Study of the R3 Biolox Delta Ceramic Acetabular System - Europe
The purpose of this prospective, multicenter, single arm study is to confirm the long-term safety and effectiveness of the R3 delta Ceramic Acetabular System PMA (P150030) by evaluating long-term (10 years after surgery)…
- Trial name
- R3 EU PAS (NCT03566082)
- Where
- 5 sites in Belgium, Finland and 2 more
- Volunteers
- 135 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Osteoarthritis
Study of Meloxicam Capsules in Subjects With Osteoarthritis of the Knee or Hip
The purpose of this study is to evaluate the safety of Meloxicam SoluMatrix Capsules for up to 52 weeks in subjects with pain due to osteoarthritis (OA) of the knee or hip
- Trial name
- NCT01801735
- Testing
- Meloxicam Test Capsules
- Where
- 40 sites in United States
- Volunteers
- 600 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Osteoarthritis, Knee, Osteoarthritis, Hip
Improving Resilience and Longevity for Workers Through Exercise
The purpose of this study is to examine the impact of an OA-specific aerobic and strengthening exercise program, delivered within the workplace, on mobility, pain, physical capacity, and resilience among workers with knee or hip…
- Trial name
- NCT03050320
- Testing
- Exercise, No Exercise
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- McMaster University
Osteoarthritis, Knee, Osteoarthritis, Hip
Study Of "Continuous Use" Of Celecoxib Vs. "Usual or Intermittent Use"
To determine whether "continuous use" of celecoxib over a 6-month period is more efficacious than "usual or intermittent use" in preventing spontaneous osteoarthritis flares of the knee and hip.
- Trial name
- NCT00139776
- Testing
- Celecoxib
- Where
- 124 sites in United States, Belgium and 6 more
- Volunteers
- 875 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Osteoarthritis, Hip
A Study of the Safety and Effectiveness of Synvisc-One® (Hylan G-F 20) in Patients With Primary Osteoarthritis of the Hip
The primary objective of this study was to demonstrate any changes in assessments of pain for participants receiving Synvisc-One compared to control.
- Trial name
- NCT01618708
- Testing
- Synvisc-One (hylan G-F 20)
- Where
- 48 sites in United States, Canada
- Volunteers
- 357 people
- Sponsor
- Genzyme, a Sanofi Company
Osteoarthritis
Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)
The purpose of this study is to test an osteoarthritis (OA) primary care Physical activity Care Pathway (OA-PCP), a scalable intervention that includes: 1) a practical process for physical inactivity screening in primary care, 2)…
- Trial name
- OA-PCP (NCT04533711)
- Testing
- OA-PCP Intervention, Attention Control
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of North Carolina, Chapel Hill
Femoro Acetabular Impingement
A Study Comparing Fascia Iliaca Blockade vs Extracapsular Local Field Infiltration With Liposomal Bupivacaine
The purpose of this study is to compare the effectiveness of fascia iliaca blockade vs local field infiltration with liposomal bupivicaine in controlling pain, narcotic utilization and falls in the postoperative period following…
- Trial name
- NCT04114058
- Testing
- liposomal bupivicaine, Fascia iliaca blockade
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Cedars-Sinai Medical Center
Osteoarthritis, Arthroplasty
Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty
The primary objective of this study is to examine whether there is a difference in the level of resting pain following total hip arthroplasty with an anterior approach with use of a psoas compartment block versus a local…
- Trial name
- NCT02658149
- Testing
- Ropivacaine with NaCl, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Corewell Health East
Hip Osteoarthritis, Noninflammatory Degenerative Joint Disease
Randomized Controlled RSA Study Comparing the Taperloc Complete Versus the Taperloc Complete Microplasty.
This is a single center, prospective, randomized controlled study. The primary objective of this study is to measure migration over two years with RSA.
- Conditions
- Hip Osteoarthritis, Noninflammatory Degenerative Joint Disease, Avascular Necrosis, Correction of Functional Deformity
- Trial name
- NCT03409666
- Testing
- Taperloc Complete Microplasty stem, Taperloc Complete Reduced Distal stem
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Hip Osteoarthritis
Platelet Rich Plasma vs Hyaluronic-Acid in Hip OA (Osteoarthritis)
The objective of this study is to compare the clinical efficacy of intra-articular injections of autologous platelet rich plasma (PRP) vs hyaluronic acid (HA) for symptomatic early osteoarthritis (OA) of the hip.
- Trial name
- NCT01920152
- Testing
- PRP, Hyaluronic Acid
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Colorado, Denver
Dysplasia; Hip, Prosthesis Survival
Long-term Outcomes of Conical Tapered Stems in Cementless Total Hip Arthroplasty Due to Congenital Hip Pathologies
A retrospective consecutive population of patients treated with conical tapered stems in cementless total hip arthroplasty for osteoarthritis due to congenital hip pathologies will be selected.
- Trial name
- RetroCone (NCT04748458)
- Testing
- Conical tapered stem
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Istituto Ortopedico Rizzoli
Arthroplasty, Replacement, Hip
Restoration® Anatomic Dual Mobility (ADM) X3® Acetabular System Study
The purpose of this study is to evaluate the success rate of cementless primary hip replacement with the Restoration® ADM X3® Acetabular System as compared to other primary hip systems in the literature, through absence of…
- Trial name
- NCT01420237
- Testing
- Restoration ADM X3 Device
- Where
- 12 sites in United States, Canada and 1 more
- Volunteers
- 367 people
- Sponsor
- Stryker Orthopaedics
Osteoarthritis, Knee, Osteoarthritis, Hip
OA Clinic-Community CARE Model
The purpose of this study is to test the OA Clinic-Community CARE Model (OA CARE) which will address all recommended components of knee/hip (osteoarthritis) OA care, include interventions for both patients and primary care…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity
- Trial name
- OA CARE (NCT05349500)
- Testing
- OA CARE Intervention, Usual Care control group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Prosthesis-related Infections, Wound Complications
Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.
The purpose of this study is to determine the efficacy of a negative pressure wound therapy (NPWT) system after revision total knee and hip arthroplasty in patients at high risk for infection.
- Conditions
- Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02127281
- Testing
- Prevena
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The Cleveland Clinic
Knee Osteoarthritis, Hip Osteoarthritis
Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty
This research is being done to see if there is a difference between two different spinal anesthetics (Mepivacaine vs. Bupivacaine) as it relates to reducing post-operative complications and the time it takes for subjects to…
- Trial name
- NCT03838874
- Testing
- Low-Dose Bupivacaine, Mepivacaine
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Mayo Clinic
Arthroplasty
A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hip Replacement Surgery Compared With Oxycodone and Placebo Followed by a Voluntary Open-Label Extension For Safety
The purpose of this study is to test in patients who have had hip replacement surgery the effectiveness (level of pain control) and the safety of 3 different dose levels of CG5503 compared with placebo and with 10-mg oxycodone…
- Trial name
- NCT00364533
- Testing
- Tapentadol IR (CG5503), Oxycodone HCL IR
- Where
- 77 sites in United States, Belgium and 6 more
- Volunteers
- 367 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Arthropathy of Hip, Arthropathy of Knee
Tranexamic Acid Dosing for Total Joint Arthroplasty
The purpose of this study is to determine the effect of increasing doses of tranexamic acid (TXA) on limiting blood loss during total knee and total hip arthroplasty as defined by a change in hemoglobin from pre-operative…
- Trial name
- NCT02584725
- Testing
- Tranexamic Acid
- Volunteers
- 84 people
- Sponsor
- Columbia University
Osteoarthritis, Knee / Osteoarthritis, Hip
Efficacy and Safety of MT-5547 in Patients With Osteoarthritis Accompanied by Moderate to Severe Pain
The objective of this study is to verify the superiority of 16 weeks of MT-5547 treatment to placebo, as evidenced by the WOMAC pain score (the efficacy outcome measure), in patients with osteoarthritis of the knee or hip.
- Trial name
- NCT03245008
- Testing
- MT-5547
- Where
- 27 sites in Japan
- Volunteers
- 626 people
- Sponsor
- Tanabe Pharma Corporation
Osteoarthritis, Rheumatoid Arthritis
Clinical Study Comparing Two Implant Surface Finishes in Patients Undergoing Cementless Total Hip Replacement
Prospective, randomized study of Summit Porocoat versus Summit DuoFix HA in total hip arthroplasty
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- SPD (NCT00306917)
- Testing
- non-coated femoral hip stem, coated femoral hip stem
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- DePuy Orthopaedics