Clinical trials: Hip Osteoarthritis
Osteoarthritis
Intra-articular Tranexamic Acid in the Reduction of Blood Transfusions in Primary Total Hip and Total Knee Arthroplasty
This is a randomized, double blinded, controlled trial in patients undergoing elective Total Knee Arthroplasty (TKA) and Total Hip Arthroplasty (THA).
- Trial name
- NCT02393963
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Innovation Centre
Hip Osteoarthritis, Hip Arthropathy
Comparative Study of Minimally Invasive Surgical Approaches for Total Hip Arthroplasty
Total hip arthroplasty is a method of choice for treating advanced osteoarthritis of the hip and one of the most frequent orthopedic procedures.
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Minimal Invasive, Anterior Approach
- Trial name
- NCT04311125
- Testing
- Mini posterior approach Total Hip Replacement, Anterior approach total hip replacement without a traction table, Anterior approach total hip replacement with a traction table
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- National and Kapodistrian University of Athens
Hip Osteoarthritis, Hip Impingement Syndrome
Losartan to Improve Hip Microfracture
Phase I/IIA randomized, double-blind, placebo-controlled clinical trial to assess safety and efficacy of oral losartan for improving cartilage repair following microfracture to treat focal cartilage defects during hip arthroscopy.
- Conditions
- Hip Osteoarthritis, Hip Impingement Syndrome, Cartilage Damage, Fibrosis
- Trial name
- NCT04212650
- Testing
- Losartan
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Steadman Philippon Research Institute
Hip Osteoarthritis, Chronic Pain
Comparative Study Between Steroid Plus Anesthetic Block and CRF in Participants With Hip Osteoarthritis
This will be a prospective, multi-center, double-blinded, randomized study designed to compare the efficacy of Conventional Radiofrequency (CRF) and the anesthetic block of the anterior sensory branches to the hip to control pain…
- Trial name
- NCT04876859
- Testing
- CRF of anterior sensitive branches to the hip, Anesthetic block with steroid injection of anterior sensitive branches to the hip
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Brasilia
Osteoarthritis, Hip
Selecting the Right Hip Prosthesis for Young Patients
There have been no previously published clinical randomized studies comparing Primoris®, short stem, hip prosthesis with standard uncemented hip arthroplasty in relation to bone density and function development.
- Trial name
- NCT03279276
- Testing
- Total Hip Arthroplasty
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Knee Osteoarthritis, Hip Osteoarthritis
An Analysis of the Outcomes From Protocolized Perioperative Care for Patients Receiving Total Hip or Knee Arthroplasty
The care for patients receiving total hip and knee arthroplasty at the University of Arkansas for Medical Sciences has followed a structured care pathway since July 2015.
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Knee Arthritis, Hip Arthritis
- Trial name
- NCT03071250
- Testing
- Total knee or Hip Arthroplasty
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Arkansas
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.
Total Hip Replacement (Non-inflammatory)
Post Approval Study: NOVATION Ceramic Articulation Hip System
The purpose of this study is to collect and evaluate long-term safety and effectiveness data on the Exactech® NOVATION ™ Ceramic Articulation Hip System ("NOVATION ™ Ceramic AHS").
- Trial name
- NCT00715143
- Testing
- Novation Ceramic
- Where
- 5 sites in United States
- Volunteers
- 126 people
- Sponsor
- Exactech
Hip Osteoarthritis
Use of Leukocyte-Rich PRP or Leukocyte-Free PRP in the Treatment of Hip Osteoarthritis
The aim of the study is to compare the efficacy up to 12 months of two different types of PRP (PRP with leukocytes vs PRP depleted of leukocytes) in the echo-guided infiltrative treatment of hip OA by including 230 patients in…
- Trial name
- PRP22-Hip (NCT05497349)
- Testing
- Leukocyte Rich- PRP injection, Leukocyte Poor- PRP injection
- Where
- Italy
- Volunteers
- 230 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
Hydroxyethyl Starch and Renal Function After Hip Replacement Surgery
The purpose of this project is to investigate if hydroxyethyl starch (HES) is potential nephrotoxic and examine the effects on the circulation and kidneys during administration of HES during surgery.
- Trial name
- VOHO (NCT01486576)
- Testing
- Voluven (Hydroxyethyl starch 130/0,4), Sodium Chloride 9 mg/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Regional Hospital Holstebro
Osteoarthritis of the Hip
The Metaphyseal Hip Prosthesis - Total Hip
The purpose of this study is to analyze stability, safety and efficacy of the Metaphyseal Hip Prosthesis (MHP) compared to the Stanmore hip replacement.
- Trial name
- NCT01501955
- Testing
- Metaphyseal Hip Prosthesis, Stanmore
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Zimmer Biomet
Hip Osteoarthritis
Effect of Local Infiltration Anesthesia in a Hip Arthroplasty Fast Track Program.
Fast-track programs in Orthopaedic Surgery require early motion that can only be achieved by optimal pain management protocols. Multimodal analgesia protocols including local infiltration anesthesia (LIA) have obtained excellent…
- Trial name
- NCT03513276
- Testing
- 100cc of 2% ropivacaine, Saline Solution, Adrenaline 10mcg/ml
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Hospital Mutua de Terrassa
Coxarthrosis; Primary, Coxarthrosis; Secondary
Is the Dynamic of the Pelvic Bone Altered After a Total Hip Replacement ?
Total hip replacement is one of the most common surgical procedure in France. In 2010, an estimated 147 513 total hip procedures were performed. This number is constantly increasing.
- Trial name
- DYPAMAT (NCT04587440)
- Testing
- Pelvic inclination measurement
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Osteoarthritis, Pain
Study of Efficacy, Safety of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3001
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as adjunctive therapy compared with placebo in participants with chronic moderate to severe pain and functional impairment from knee…
- Trial name
- NCT02336685
- Testing
- Fulranumab 1 mg, Fulranumab 3 mg, Opioid
- Where
- 53 sites in United States, Canada and 4 more
- Volunteers
- 79 people
- Sponsor
- Janssen Research & Development, LLC
Total Hip Arthroplasty
Strength and Function Following Total Hip Arthroplasty
To determine if patients who receive an 8 week, comprehensive, multi-component rehabilitation program (CMC) have better strength and functional performance compared to a control group (CON).
- Trial name
- NCT01817010
- Testing
- Multi-Component Rehabilitation (CMC), Control (CON)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Colorado, Denver
Hip Osteoarthritis
Hip Osteoarthritis: Effects of Exercise Programs on Pain and Disability
Osteoarthritis is the most common form of arthritis in the United States. It is estimated that 20 million Americans have arthritis, and the annual societal cost is $95 billion.
- Trial name
- NCT00682617
- Testing
- Structured exercise program, Waitlist, delayed intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Osteoarthritis of the Knee, Osteoarthritis of the Hip
Cardiovascular And Metabolic Risk After Arthroplasty
Osteoarthritis is a chronic joint disease that lacks curative therapy. Epidemiological studies show increase in the burden of disease. Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis.
- Conditions
- Osteoarthritis of the Knee, Osteoarthritis of the Hip, Cardiovascular Diseases, Metabolic Syndrome
- Trial name
- CAMERA (NCT06211465)
- Testing
- Total joint arthroplasty
- Where
- Estonia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Anesthesia, Hip Osteoarthritis
The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Postoperative recovery is always worrisome to the elder patients undergoing Total Hip Replacement (THR). Peripheral Nerve Blocks (PNBs), lumbar plexus block combined with sciatic nerve blocks, may be alterative anaesthesia style…
- Trial name
- NCT01782612
- Testing
- Multimodal analgesic techniques, Total uni-Hip Replacement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Junle Liu
Osteoarthritis
Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)
The purpose of this study is to test an osteoarthritis (OA) primary care Physical activity Care Pathway (OA-PCP), a scalable intervention that includes: 1) a practical process for physical inactivity screening in primary care, 2)…
- Trial name
- OA-PCP (NCT04533711)
- Testing
- OA-PCP Intervention, Attention Control
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of North Carolina, Chapel Hill
Hip Arthropathy, Hip Osteoarthritis
Erector Spinae vs. PENG Block for Total Hip Arthroplasty
Effect of PENG block and ESPB on pain management, and NLR and PLR following knee arthroplasty
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Pain Chronic
- Trial name
- NCT06083428
- Testing
- Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block, Ropivacaine 0.2% Injectable Solution - PENG block, Control Test
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
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