Clinical trials: Hip Prosthesis
Analgesia
Assessment of PENG Block Analgesia Versus Intra-articular Infiltration in Hip Prosthesis Surgery
After hip arthroplasty, pain intensity is maximum within the first 6 hours and is then estimated to last between 36 and 72 hours. Pain management (analgesia) after hip prosthetic surgery remains a challenge.
- Trial name
- API (NCT06675916)
- Testing
- PENG Block with lidocaine hydrochloride, Intra-articular infiltration with lidocaine hydrochloride
- Where
- France
- Volunteers
- 60 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Coxarthritis
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Corail Prosthesis With or Without Collar Design
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Corail prosthesis with or without collar design. Randomized study design focusing on radiolucent lines on standard x-ray.
- Trial name
- NCT02960633
- Testing
- Corail with collar., Corail without collar.
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ZOL
Hip Osteoarthritis
Study of the Clinical and Radiographic Results of a Fixed Polyethylene Posteriorly Stabilized Cemented Total Knee Prosthesis With a Minimum Follow-up of 1 Year.
The knee replacement market is experiencing constant growth. Alongside this growth, there is also an increasing interest in customizing implantation based on specific phenotypes to restore the morphology of the native knee.
- Trial name
- PTG-Anatomic (NCT07313449)
- Where
- France
- Volunteers
- 960 people
- Sponsor
- University Hospital, Strasbourg, France
Hip Fractures
Uncemented Compared to Cemented Femoral Stems in Total Hip Arthroplasty
The purpose of this study is to evaluate whether an uncemented hip prosthesis is as safe as an cemented hip prosthesis for patients undergoing total hip arthroplasty surgery following a displaced femoral neck fracture.
- Trial name
- CHANCE (NCT02247791)
- Testing
- Uncemented femoral stem, Cemented femoral stem
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Danderyd Hospital
Osteoarthritis
Five and Ten Year Results of the CMK21 Hip System
Five and ten year results of the CMK21 Hip system
- Trial name
- CMK21 (NCT03908151)
- Testing
- CMK21 Hip system
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew, Inc.
Hip Fracture, Postoperative Pain
Effect of PENG Block on Postoperative Tramadol Consumption in Partial Hip Prosthesis Surgery
This study aims to evaluate the effect of ultrasound-guided pericapsular nerve group (PENG) block on postoperative tramadol consumption, pain scores, and clinical outcomes in patients undergoing partial hip prosthesis surgery.
- Trial name
- PENG-PKP (NCT07534137)
- Testing
- PENG Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- University of Gaziantep
Hip Injuries, Surgery
Benefit of 3-D Planning in Total Hip Replacement. A Prospective Randomized Study
In this prospective randomized four-armed study the investigators aim to compare wheter 3-D planning, which necessitates preoperative CT acquisition and sophisticated planning together with engineers, results in measurable…
- Conditions
- Hip Injuries, Surgery, Prosthesis User
- Trial name
- NCT05120063
- Testing
- SPS monoblock stem, Symbios, Quadra-H, Medacta, 3D planning of THR
- Volunteers
- 133 people
- Sponsor
- Balgrist University Hospital
Prosthetic Joint Infection, Hip Prosthesis Infection
Long Term Follow-up of Patients With Prosthetic Joint Infection of the Hip Treated at University Hospitals Leuven
Prosthetic Joint Infection (PJI) of a Total Hip Replacement (THR) is a disastrous complication of an otherwise extremely successful surgical procedure.
- Trial name
- PROFITH (NCT05000723)
- Testing
- Standard of care
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Osteoarthritis, Hip
Efficacy of a New Resurfacing Hip Prosthesis
The purpose of this study is to compare the articular surface replacement (ASR) prosthesis placed by the conventional positioning method and the ASR prosthesis placed by 'computer assisted surgery' (CAS) in variation between pre…
- Trial name
- NCT00391937
- Testing
- Articular Surface Replacement (ASR) hip prosthesis
- Where
- 6 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Erasmus Medical Center
Primary Arthrosis, Osteoarthritis
Wear Measurements of E-Poly in an Uncemented THA With Either 32 or 36 mm Caput of Ceramics.
The aim of the study is to compare polyethylene wear in an uncemented total hip prosthesis with 3rd. generation highly cross-linked polyethylene with a 32 mm ceramic femoral head compared to a 36 mm ceramic head.
- Trial name
- NCT00804388
- Testing
- Total hip arthroplasty
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Lovisenberg Diakonale Hospital
Hip Prosthesis Infection
Prosthetic Hip Infections: Prospective Study
Data from large prospective cohort studies of prosthetic joint infections are lacking. Aim of this study: analyzing prospectively the incidence of reinfection in patients with prosthetic hip infections who underwent surgery and…
- Trial name
- PHIPS (NCT01963520)
- Where
- France
- Volunteers
- 347 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Hip Arthrosis
Hip Prosthesis Components Position
The purpose of the study is
- Trial name
- NCT05406271
- Testing
- Intraoperative fluoroscopy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Mateusz Szymczak
Staphylococcal Infections, Methicillin-resistant Staphylococcus Aureus
Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty
This study will evaluate the safety and effectiveness of daptomycin, an antibiotic compared to another one which is vancomycin when given around the time of joint replacement surgery.
- Trial name
- NCT01196169
- Testing
- Daptomycin, Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Mountain Home Research & Education Corporation
Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
ROADMAP Clinical Trial
Artificial joint infections are treated with different types of antibiotics and surgery. The ROADMAP study aims to find out which treatments currently used work best in regards to surgery, antibiotic choice as well as the time…
- Conditions
- Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Large Joint Prosthetic Joint Infections
- Trial name
- ROADMAP (NCT06771050)
- Testing
- Debridement and Implant Retention (DAIR), Antibiotic Choice, Antibiotic duration Part A - Single stage revision
- Where
- 43 sites in Australia, New Zealand
- Volunteers
- 2,500 people
- Sponsor
- University of Newcastle, Australia
Prosthesis-Related Infections, Hip Prosthesis Infection
Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy.
It is not known in the literature how much sonication affects the patient's treatment. Another important issue is that the place of this method in diagnosis is not clear.
- Conditions
- Prosthesis-Related Infections, Hip Prosthesis Infection, Joint Infection, Biofilm
- Trial name
- NCT04304885
- Testing
- Sonication method
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Hip Arthropathy
Ambispective Study to Assess the Safety and the Performance of SAGITTA EVL R Stem
This clinical study is conducted to collect data on hip arthroplasty with the SAGITTA EVL-R revision femoral stems manufactured by SERF.
- Trial name
- 2022-09 (NCT06096155)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Societe dEtude, de Recherche et de Fabrication
Prosthesis-Related Infections
Dosing of Antibiotics During Reimplantation of Infected Knee and Hip Prostheses
The purpose of the study is to evaluate the concentrations of antibiotics used as empirical treatment in serum and periprosthetic tissues during reimplantation of infected hip and knee prostheses
- Trial name
- DOSOS (NCT02860767)
- Where
- 5 sites in France
- Volunteers
- 30 people
- Sponsor
- Tourcoing Hospital
Amputation, Prosthesis User
Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators
The goal of this study is to find out if using microprocessor-controlled prosthetic knees (MPKs), prosthetic knees with a built-in computer, improves health outcomes related to falls in adults who use above-knee prostheses.
- Conditions
- Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower
- Trial name
- NCT06937242
- Testing
- Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hanger Institute for Clinical Research and Education, LLC
Aseptic Loosening, Osteolysis
Post-Market Study of the Modular Revision Hip System
The purpose of this study is to examine the short term efficacy of the MRH system as well as determine if operating room time is decreased using this simple, two-tray system.
- Conditions
- Aseptic Loosening, Osteolysis, Traumatic Fracture, Failed Total Hip Implant
- Trial name
- MRHS (NCT01464645)
- Testing
- Modular Revision Hip System
- Where
- 6 sites in United States
- Volunteers
- 16 people
- Sponsor
- Encore Medical, L.P.
Periprosthetic Fracture of the Femur
Periprosthetic Fractures of the Femur Treated by Osteosynthesis
Observational retrospective study on 36 consecutive patients having had surgery for a periprosthetic fracture of the femur between 2010 and 2015.
- Trial name
- NCT02854566
- Testing
- osteosynthesis
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Brugmann University Hospital