Clinical trials: Hip Replacement, Total
Coxarthrosis, Muscle Weakness
Does Capsulectomy, Performed in Total Hip Arthroplasty With a Direct Anterior Approach Cause Knee Extension Strength Loss?
Total hip arthroplasty (THA) has been successful in relieving pain and restoring function in patients with advanced arthritis of the hip joint.
- Trial name
- NCT04500093
- Testing
- Capsulotomy with Repair, Capsuloectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Coxarthrosis, Arthroplasties Hip Replacement
Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty
The primary aim of this study is to test if etoricoxib decreases the perioperative blood loss compared to diclofenac. Secondary questions to be explored are: Does etoricoxib prevent Heterotopic ossification after Total Hip…
- Conditions
- Coxarthrosis, Arthroplasties Hip Replacement, Perioperative Blood Loss
- Trial name
- NCT01229774
- Testing
- Etoricoxib, Diclofenac
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Regensburg
Avascular Necrosis, Osteoarthritis
Continuum™ Metal Bearing System in Total Hip Arthroplasty
The study is a multi-center, prospective, non-controlled, consecutive cohort post market surveillance study. The objective of this study is to obtain survival and outcome data on the Continuum Metal Bearing System in primary…
- Conditions
- Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Post-traumatic; Arthrosis
- Trial name
- NCT03382652
- Testing
- Metal-on-Metal Articulation
- Where
- 3 sites in United States, Finland
- Volunteers
- 83 people
- Sponsor
- Zimmer Biomet
Anemia
A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo to Reduce the Need for Blood Transfusions and Reduce the Occurrence of Severe Anemia During the Time Period Surrounding Total Hip Replacement Surgery
The purpose of this study is to evaluate the safety and effectiveness of two different dosing schedules of epoetin alfa versus placebo for decreasing the need for blood transfusions and preventing the occurrence of severe anemia…
- Trial name
- NCT00269958
- Testing
- epoetin alfa
- Volunteers
- 208 people
- Sponsor
- Janssen-Ortho Inc., Canada
Total Hip Replacement
Twenty-Four Seven Functional Status in Total Hip Replacement
The goal of this observational study is to define digital remote monitoring measures for functional status (activities of daily living) in patients receiving total hip replacement.
- Trial name
- LEARNT (NCT06209216)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Koneksa Health
Antibiotic Prophylaxis Surgery
Efficacy and Safety of Intraosseous Antibiotic Prophylaxis in Total Hip Replacement
The goal of this clinical trial is to learn if intraosseous antibiotic (cefazolin) administration can improve antibiotic levels in adults undergoing primary total hip replacement.
- Trial name
- NCT07549542
- Testing
- CeFAZolin 1000 MG, Saline (0.9%, sterile, for infusion)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Immune Responses, Post Operative Recovery
Comparative Study Between the Effects of Deep Versus Moderate Neuromuscular Blockade on Postoperative Recovery and Immune Function in Patients Undergoing Total Hip Replacement Surgery.
. The investigators hypothesized that DNMB ( Deep NeuroMuscular Block) would yield superior postoperative recovery quality and attenuate the surgery-induced immune suppression compared to MNMB ( Moderate NeuroMuscular Block)in…
- Trial name
- NCT07870954
- Testing
- ToF ( Train of Four) Scan
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Total Hip Arthroplasty, Acetabular Cup
A Prospective RSA and Clinical Evaluation of the Trident II Acetabular Cup
The objective of this study is to use radiostereometric analysis (RSA) and clinical outcome measures to evaluate early post-operative implant stability and the clinical performance of Stryker's Trident II Acetabular Cup.
- Trial name
- NCT03261986
- Testing
- Radiostereometric Analysis, total hip arthroplasty with RSA bead implantation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Midwest Orthopaedics at Rush
Bone Mineral Density
Changes of Bone Mineral Density in Total Hip Arthroplasty
The study was performed as a prospective, single center study at the Department of Orthopedics, Sacred Heart of Jesus Hospital Vienna, Austria. 117 patients were enrolled in a from January 2016 to May 2017.
- Trial name
- NCT04962854
- Volunteers
- 117 people
- Sponsor
- St. Vincent Hospital, Vienna
Excessive Amount of Blood / Fluid Transfusion
Iron and Vitamin Adminstration Prior to Joint Replacement to Prevent Transfusion
To establish the efficacy of screening for anemia and treatment of mild anemia with iron and vitamins prior to THR and TKR as a means of increasing hemoglobin and reducing perioperative allogeneic blood transfusion.
- Trial name
- NCT01676740
- Testing
- Iron Supplement,
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Meir Medical Center
Optimized Treatment
Hemi Artificial Hipjoint Versus Total Artificial Hipjoint
This is a Randomized Controlled Trial study comparing hemialloplastik versus total joint replacement.
- Trial name
- THA (NCT01432691)
- Testing
- Hemi (hemialloplastik)
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Hvidovre University Hospital
Pain, Postoperative
Combination Effects of Pregabalin and Dexmedetomidine on Postoperative Pain
Pregabalin and dexmedetomidine have been introduced to manage postoperative pain. The present study aimed to evaluate the effect of the combination of two drugs on pain relief in patients undergoing total knee or hip arthroplasty…
- Trial name
- NCT03512574
- Testing
- Pregabalin, Dexmedetomidine, Pregabalin and dexmedetomidine
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Total Hip Replacement System
Ceramic on Metal Total Hip Replacement System Multi-Center,Investigational Device Exemption Clinical Trial
The purpose of this study is to demonstrate non-inferiority of the Ceramic on Metal Total Hip when compared to a TRANSCEND® historical control group of patients with primary total hip replacement.
- Trial name
- COM (NCT00820443)
- Testing
- Ceramic on metal prosthesis
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- MicroPort Orthopedics Inc.
Postoperative Pain, Total Hip Replacement
Study of the QUadratus Lumborum Bloc in Total Hip ARthroplasty: Efficacy and Safety
The purpose of this prospective research study is to determine the best way to manage post-operative pain after a total hip arthroplasty. Currently, there is no standard of care for managing post-operative pain in these patients.
- Trial name
- SQUARE (NCT03189290)
- Testing
- posterior Quadratus Lumborum Block (QLB)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis, Arthritis
Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty
The purpose of the study is to determine whether crosslinked Marathon and standard Enduron polyethylene liners show differences in bone loss around the hip implant.
- Conditions
- Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT01121146
- Testing
- Total Hip Replacement
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Anderson Orthopaedic Research Institute
Rheumatoid Arthritis, Osteoarthritis
A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the Summit™ hip in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208390
- Testing
- Summit Tapered Hip System
- Where
- 5 sites in China, Hong Kong and 3 more
- Volunteers
- 275 people
- Sponsor
- DePuy International
Hip Osteoarthritis, Hip Arthropathy
Dexamethasone for ESPB in Total Hip Arthroplasty
Effect of adding Dexamethasone to Erector Spinae Plane Block in Patients undergoing Total Hip Arthroplasty
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Arthritis
- Trial name
- NCT06789042
- Testing
- 0.9%NaCl, Dexamethasone 4mg
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Total Hip Arthroplasty, Computer-Assisted Surgery
Pre-Op THA Modelling
Replacing diseased hip joints with prosthetic implants in a procedure called total hip arthroplasty (THA) is associated with high rates of patient satisfaction, pain relief, and functional improvement when the implant is…
- Trial name
- NCT05221554
- Testing
- Imageless computer-navigated THA surgery, Standard of care THA surgery, CT-based Computer-navigated THA surgery
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Supra-Iliac Anterior Quadratus Lumborum Block, Pericapsular Nerve Group Block
Supra-Iliac Anterior Quadratus Lumborum Block and Pericapsular Nerve Group (PENG) Block for Analgesia After Total Hip Arthroplasty
This study aims to compare the analgesic efficacy of supra-iliac anterior quadratus lumborum block (SA-QLB) and pericapsular nerve group (PENG) block in patients undergoing total hip arthroplasty (THA).
- Conditions
- Supra-Iliac Anterior Quadratus Lumborum Block, Pericapsular Nerve Group Block, Analgesia, Total Hip Arthroplasty
- Trial name
- NCT07606794
- Testing
- Supra-iliac anterior quadratus lumborum block, Pericapsular nerve group block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Hip Replacement
Surgical Adhesive Drapes for Prevention and Healing of Wound Infections After Total Hip Arthroplasty
The purpose of this study is to support the rational use of iodophor-impregnated surgical adhesive drapes for preventing wound infections after total hip arthroplasty.
- Trial name
- NCT02707302
- Testing
- Iodophor-impregnated adhesive drapes group, Iodophor-free adhesive drapes group
- Volunteers
- 120 people
- Sponsor
- Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
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