Clinical trials: Hip Replacement, Total
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Preoperative Fasting and the Gut Microbiome Before Hip Replacement
Postoperative complications occur in 5-15% of patients undergoing elective primary total hip arthroplasty (THA), including periprosthetic joint infection (PJI), thrombosis, wound healing disorders, and metabolic dysregulation.
- Conditions
- Hip Osteoarthritis, Arthroplasty, Replacement, Hip, Postoperative Complications, Surgical Wound Infection
- Trial name
- PreFAST-Hip (NCT07651462)
- Testing
- Buchinger Fastenbox + intermittent fasting (20-day preoperative schedule)
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Charite University, Berlin, Germany
Hip Replacement, Total
Tranexamic Acid Versus Placebo for the Reduction of Blood Loss in Total Hip Replacement Surgery
The bleeding caused by hip replacement surgery (CRT) is an important source of demand for blood in the hospital. Tranexamic acid (TXA) is a drug that has proved useful in reducing bleeding associated with other surgeries and CRT…
- Trial name
- TXA-CRT (NCT01199627)
- Testing
- A, B, C
- Where
- Spain
- Volunteers
- 114 people
- Sponsor
- Basque Health Service
Hip Arthroplasty
Rehabilitation to Patients Over 65 Years Undergoing THA
Patients over 65 years do not have a self care ability the surgery benefits them. The aim of this study is development of a rehabilitation program based on patients' self-rated health. 1.
- Trial name
- NCT00226070
- Testing
- interview and advising, 3 follow up interviews and personal advising, interview SF-36 self rated health
- Where
- 6 sites in Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
PHYSİOTHERAPY
Effects Of A Home Based Exercise Program Following Total Hip Arthroplasty
The aim of this study is to examine the effects of home-based exercise on pain-related factors, postural control and early functional parameters in individuals undergoing total hip arthroplasty.
- Trial name
- NCT06274866
- Testing
- exercise program, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Halic University
Total Hip Arthroplasty
Anterior Capsulectomy vs. Repair in Direct Anterior THA
Randomized prospective study comparing the anterior capsule repair vs capsulectomy with regards to post-operative pain and range of motion outcomes in elective primary unilateral direct anterior approach THA for osteoarthritis.
- Trial name
- NCT01621932
- Testing
- Direct anterior approach with capsulectomy, Direct anterior approach without capsulectomy
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Orthostatic Intolerance, Orthostatic Hypotension
Pathophysiologic Hemodynamics After Primary Unilateral Total Hip Arthroplasty in Patients Receiving ACEIs and ARBs
Incidence and pathophysiologic hemodynamics of postoperative orthostatic intolerance and orthostatic hypotension in patients receiving antihypertensives
- Trial name
- NCT04842058
- Testing
- Mobilisation procedure
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Hvidovre University Hospital
Anesthesia, Orthopedic Surgery
Does Midazolam Cause Effective Anterograde Amnesia in Orthopedic Surgeries?
Spinal anesthesia is one of the commonest choices of anesthesia for infraumbilical surgeries.The use of sedation has markedly increased patients' comfort and acceptance towards spinal anesthesia.
- Trial name
- NCT04232150
- Testing
- single-dose midazolam for sedation under spinal anesthesia., Double-dose midazolam for sedation under spinal anesthesia., spinal anesthesia with no sedation.
- Where
- Jordan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Obturator Nerve Block, Total Hip Replacement
Postoperative Analgesia After Elective Hip Surgery - Effect of Obturator Nerve Blockade
The study investigates the effect of an obturator nerve block on the postoperative pain and opioid consumption after total hip replacement.
- Trial name
- NCT03064165
- Testing
- Bupivacaine-epinephrine, Obturator nerve block, Sodium Chloride 9mg/mL
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- University of Aarhus
Total Hip Arthroplasty
The Effect of Preoperative Information and Education in the Clinical Outcome of Total Hip Arthroplasty
Preoperative patient information and education is an essential aspect of modern surgical care, particularly for patients undergoing total hip arthroplasty (THA).
- Trial name
- NCT06662981
- Testing
- preoparative information and education
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Prosthesis-Related Infections, Arthroplasty, Replacement, Hip
Exploring Novel Diagnostic Tools for Periprosthetic Joint Infection
Joint replacement is a valuable surgical intervention that improves quality of life, provides pain relief, and restores function of patients.
- Conditions
- Prosthesis-Related Infections, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- VECTOR-PJI (NCT05582460)
- Testing
- Reporter Gene Assay, Flow Cytometry
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Rijnstate Hospital
Postoperative Pain, Analgesia
PENG Block Combined to Wound Infiltration for Hip Replacement
This study analyze the effect of Pericapsular Nerve Group (PENG) Block combined to wound infiltration for analgesia after elective hip replacement.
- Conditions
- Postoperative Pain, Analgesia, Hip Arthropathy, Acute Pain
- Trial name
- NCT04306133
- Testing
- PENG block, Wound Infiltration
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Total Hip Arthroplasty, Total Hip Replacement
Total Hip Replacement With Ceramic on Ceramic Bearing- Clinical Follow-up Study
The pain and severe wear of hip joints caused by osteoarthritis, rheumatoid arthritis, avascular necrosis and trauma can be subjected to total hip replacement (THR).
- Trial name
- NCT04256291
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Orthopedic Surgery
Assessment of the Influence of Early Preoperative Consultation on Satisfaction and the Average Length of Stay of Patients Who Underwent Total Hip Arthroplasty
Arthroplastic hip surgery "fast-track" the subject of increasing interest and reduces the average length of stay and improve patient satisfaction.
- Trial name
- PTHJ-8 (NCT02771041)
- Testing
- medical consultation 8 days before surgery
- Sponsor
- Fondation Hôpital Saint-Joseph
Primary Total Hip Arthroplasty
Retrospective Observational Cohort Study of SYMBOL CUP DM 1
This is a single-center retrospective observational cohort study of consecutively operated patients who underwent primary total hip arthroplasty with a SYMBOL CUP DM HA hemispherical dual mobility acetabular implant.
- Trial name
- SYMCOR-1 (NCT04209374)
- Testing
- THA with SYMBOL CUP DM HA
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Dedienne Sante S.A.S.
Hip Osteoarthritis, Arthropathy of Hip
Total Hip Arthroplasty: Fast Track Protocol is the Future?
Fast-track total hip arthroplasty (THA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-H (NCT03875976)
- Testing
- Fast Track Protocol, Standard Care Protocol
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Bone Mineral Density
Changes of Bone Mineral Density in Total Hip Arthroplasty
The study was performed as a prospective, single center study at the Department of Orthopedics, Sacred Heart of Jesus Hospital Vienna, Austria. 117 patients were enrolled in a from January 2016 to May 2017.
- Trial name
- NCT04962854
- Volunteers
- 117 people
- Sponsor
- St. Vincent Hospital, Vienna
Arthroplasty, Replacement, Hip, Hip Replacement, Total
Does Rapid Mobilisation Improve Length of Stay and Outcomes Post THR
This study looks to examine the effect of attempting initial postoperative walking with a patient following a total hip replacement.
- Trial name
- RAPID (NCT02428829)
- Testing
- Attempt walking from 4 hours post operatively, on the day of their surgery., Control - standard treatment
- Where
- United Kingdom
- Volunteers
- 212 people
- Sponsor
- The Royal Bournemouth Hospital
Osteoarthritis, Hip, Rheumatoid Arthritis
A Clinical Investigation of the Balance® Microplasty™ Hip System
The purpose of this prospective clinical data-collection is to document the performance and clinical outcomes of the Balance® Microplasty™ Hip System.
- Conditions
- Osteoarthritis, Hip, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT00699088
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Biomet Orthopedics, LLC
Orthopedic Disorder
Digital Preop-planning of Total Hip Arthroplasties
Residual leg length discrepancy is a common issue after total hip arthroplasty(THA). Digital preoperative planning may improve the accuracy of the surgical procedure and may help the surgeon to precisely predict implants sizes
- Trial name
- PLANORTHO (NCT04090372)
- Testing
- evaluation of pre-op planning using Traumacad
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Toulouse
Arthroplasty, Replacement, Hip
Total Hip Arthroplasty Outcomes With Regional and Multimodal Analgesia
The goal of this retrospective chart review is to evaluate if the implementation of lumbar plexus block placement for postoperative pain and administration of multimodal oral analgesia have improved conditions in the…
- Conditions
- Arthroplasty, Replacement, Hip, Arthritis
- Trial name
- THA (NCT02186795)
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Medical University of South Carolina
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