Clinical trials: Hip Replacement, Total
Total Knee and Total Hip Arthroplasty
TRAUMEEL for Pain After Total Knee/Hip Arthroplasty
We hypothesize that Traumeel S is more effective than placebo in reducing 48-hour mean cumulative morphine consumption following Total Knee or Hip Arthroplasty.
- Trial name
- NCT00307853
- Testing
- Traumeel S
- Where
- 2 sites in Israel
- Volunteers
- 224 people
- Sponsor
- Shaare Zedek Medical Center
Osteo Arthritis
Bone Forming at Prosthetic Surfaces. Fingerprint2
What is the intensity of F-PET uptake in healthy and osteo arthritic femur and acetabulum, compared to the uptake adjacent to four analyzed endoprosthetic components 1½ and 6 months after surgery?
- Trial name
- NCT01623687
- Testing
- Component for acetabulum (Regenerex RingLoc cup), Components for the acetabulum (Lubinus cross linked cup), Arthroplasty components are for the femur (Cemented Lubinus SP II stem)
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Uppsala University
Arthropathy of Hip
A Dose-response Study of Tranexamic Acid in Total Hip Arthroplasty
A single preoperative dose of tranexamic acid (TXA) reduces blood loss and red blood cell transfusion in primary hip arthroplasty. Numerous regimens have been tested, ranging from 10mg/kg up to 3g.
- Trial name
- PRADO (NCT03822793)
- Testing
- Group 1: perfusion of 300 mg Exacyl, Group 2: perfusion of 500 mg Exacyl, Group 3: perfusion of 1000 mg Exacyl
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Osteoarthritis
Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement
The purpose of the research is to determine if there is a difference between two of the commonly used less invasive techniques (surgical methods that use a smaller incision or cut in the skin) used to perform total hip…
- Trial name
- NCT00594893
- Testing
- Mini Incision Approach, 2 Incision Approach
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Rush University Medical Center
Educational Problems, Hip Arthroplasty
VR Simulation and Basic Skills in THA
This prospective randomised clinical trial aims to test if virtual reality (VR) simulation helps acquire basic surgical skills in total hip arthroplasty (THA) by medical students. The main question[s] it aims to answer are: 1.
- Conditions
- Educational Problems, Hip Arthroplasty, Osteoarthritis, Hip, Medical Students
- Trial name
- MD-VR-THA (NCT05807828)
- Testing
- VR simulation on basic THA skills
- Where
- Greece
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Osteoarthritis
"Score Infectivity" During Reoperation on Total Hip or Knee Prosthesis
The hip or knee is a validated treatment of end-stage osteoarthritis, and these interventions commonly make a significant improvement in the quality of life of patients. Infection can occur in 1-5% of cases.
- Trial name
- NCT02467764
- Testing
- Retrospective study
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Total Hip Replacement
Twenty-Four Seven Functional Status in Total Hip Replacement
The goal of this observational study is to define digital remote monitoring measures for functional status (activities of daily living) in patients receiving total hip replacement.
- Trial name
- LEARNT (NCT06209216)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Koneksa Health
Total Hip Arthroplasty (THA)
Clinical Performance of XPEO-E Liner in SERF Dual-mobility Cups
XPEO-E liner is CE marked under MDD 93/42/CEE by equivalency with CI E liner. No pertaining data on XPEO-E liner is yet available.
- Trial name
- 2024-01-XPEO-E (NCT06917365)
- Where
- 5 sites in France
- Volunteers
- 500 people
- Sponsor
- Societe dEtude, de Recherche et de Fabrication
Postoperative Pain, Regional Anesthesia
Comparison of Continuous Fascia Iliaca Compartment Block With Continuous PENG Block in Total Hip Replacement Cases
Adequate pain management after total hip arthroplasty (THA) is crucial for early ambulation and patient satisfaction. However, due to the hip joint's innervation complexity, the optimal regional analgesia technique for THA…
- Conditions
- Postoperative Pain, Regional Anesthesia, Pain Management, Total Hip Arthroplasty
- Trial name
- PENG (NCT06806865)
- Testing
- Periarticular nerve group block (PENG), Continuous supra-inguinal fascia iliaca compartment block (SIFICB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Sleep Patterns After Total Joint Replacement Surgery
The purpose of this study is to determine sleep patterns and sleep quality following total joint arthroplasty, in order to understand when patients should expect to return to baseline or improved sleep following total joint…
- Trial name
- NCT04896892
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Total Hip Replacement
Comparative Effects of Weight Bearing and Non-weight Bearing Exercises in Patients With Total Hip Replacement
to compare the effects of weight bearing and non-weight bearing exercises on pain, range of motion and disability in patients with total hip replacement
- Trial name
- NCT05375565
- Testing
- weight bearing exercises, non weight bearing exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Pain, Postoperative
Effect of Unilateral Erector Spinae Plane Block Versus Intrathecal Morphine on Early Mobilization After Hip Replacement
Preoperative assessment: Patients who fulfill inclusion criteria will be evaluated by medical history, physical examination and clinical laboratory tests which are a complete blood picture (CBC), kidney function tests, liver…
- Trial name
- NCT06621849
- Testing
- erector spinae plane block, Morphine
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Thromboembolism
Factor Xa Inhibitor YM150 for the Prevention of Blood Clot Formation in Veins After Scheduled Hip Replacement (ONYX-2)
The purpose of this study is to find the best possible (optimal) dose (effect versus adverse events) of YM150 to prevent the risk of blood clot formation after scheduled hip replacement surgery.
- Trial name
- NCT00353678
- Testing
- YM150
- Where
- 79 sites in Austria, Bosnia and Herzegovina and 15 more
- Volunteers
- 1,141 people
- Sponsor
- Astellas Pharma Inc
Total Hip Arthroplasty (THA), Kinesiophobia (Fear of Movement)
Effect of Cognitive Behavioral Therapy on Kinesiophobia and Functional Outcomes After Total Hip Arthroplasty.
The goal of this clinical trial study is to evaluate the effectiveness of cognitive behavioral therapy in reducing kinesiophobia and improving Clinical outcomes in postoperative patients following total hip arthroplasty The main…
- Trial name
- NCT07427758
- Testing
- Cognitive-behavioral therapy, Exercise
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL
This study aims to analyze the efficacy of intravenous tranexamic acid (TXA) in patients undergoing total hip arthroplasty (THA).
- Conditions
- Blood Loss, Surgical, Tranexamic Acid Adverse Reaction, Hip Replacement
- Trial name
- NCT03019198
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Brazil
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Hip Osteoarthritis, Total Hip Arthroplasty (THA)
QIPB vs SI-FICB for Postoperative Analgesia After Total Hip Arthroplasty
Total hip arthroplasty (THA) causes moderate-to-severe postoperative pain. The PROSPECT guideline recommends the supra-inguinal fascia iliaca compartment block (SI-FICB) for THA, whereas evidence for newer…
- Conditions
- Hip Osteoarthritis, Total Hip Arthroplasty (THA), Postoperative Pain, Acute Pain
- Trial name
- NCT07683663
- Testing
- Supra-Inguinal Fascia Iliaca Compartment Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Dokuz Eylul University
Arthropathy of Hip, Perioperative/Postoperative Complications
Living Alone is Predictive of Non-home Discharge Following Elective Total Hip Arthroplasty: a Matched-pairs Cohort Analysis
The goal of this observational study is to assess the effect of living alone on total hip arthroplasty thirty-day outcomes. The main questions it aims to answer are: Is living alone associated with discharge disposition (home…
- Trial name
- NCT06462885
- Testing
- home support, hiving alone, home support, living with others
- Where
- United States
- Volunteers
- 5,677 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Osteoarthritis
Gait Analysis and Neuromuscular Function After Primary Total Hip Replacement
This study is conducted at Odense University Hospital(OUH) in collaboration with Institute of Clinical Biomechanics and Sport Science, University of Southern Denmark and Clinical Institute, University of Southern Denmark Aim: To…
- Trial name
- RTHA and THA (NCT01229293)
- Testing
- Articular Surface Replacement (ASR), Standard Total Hip Arthroplasty (THA)
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- University of Southern Denmark
Arthroplasty, Replacement, Hip
Home-based Rehabilitation Following a Total Hip Replacement
In this study we will investigate the relation between performed exercise dose and recovery after total hip replacement (THA). A dose-response relationship is hypothesized.
- Trial name
- PHETHAS-1 (NCT03109821)
- Testing
- Home-based exercise
- Where
- Denmark
- Volunteers
- 94 people
- Sponsor
- Central Jutland Regional Hospital
Femoral Neck Fractures, Undisplaced Fracture
Hips Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients (HipSTHeR)
A registerbased RCT will investigate whether arthroplasty can decrease the reoperation rate compared to internal fixation for patients with an undisplaced femoral neck fracture (Garden I-II).
- Trial name
- HipSTHeR (NCT03966716)
- Testing
- Arthroplasty, Internal Fixation
- Where
- 25 sites in Sweden
- Volunteers
- 1,440 people
- Sponsor
- Uppsala University
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