Clinical trials: Hip Replacement, Total
Analgesia
Lumbar Erector Spinae Plane Block and Fascia Iliaca Compartment Block After Total Hip Arthroplasty
Compare the analgesic efficacy of ultrasound-guided lumbar erector spinae plane block (L-ESPB) versus fascia iliaca compartment block (FICB) in patients scheduled for total hip arthroplasty.
- Trial name
- NCT05905510
- Testing
- Lumbar Erector spinae plane block (L-ESPB), Fascia iliaca compartment block (FICB), spinal anesthesia plane block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Total Knee Replacement, Total Hip Replacement
Post Op Home Monitoring After Joint Replacements
The investigators propose to deploy an interactive device to monitor the patient's recovery and vital signs at home after joint replacements. These will be early discharge patients on the same day or the next morning.
- Trial name
- POHM (NCT02143232)
- Testing
- remote patient monitoring (Telus RPM)
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Ottawa Hospital Research Institute
Hip Osteoarthritis
The Role of Kinesiophobia in the Functional Recovery After Hip Replacement
Several authors explain as the kinesiophobia plays an important role for the recovery after orthopaedic surgery. The aim of the investigators study is to investigate if the kinesiophobia is able to influence the early recovery…
- Trial name
- kinesiofob (NCT02786121)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Ortopedico Rizzoli
Thrombosis, Hip Replacement
A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery
This study is to assess if DU176b is effective in prevention of blood clots following hip replacement surgery. The duration is 7-10 days of treatment and 30 and 60 day follow-up visits.
- Trial name
- NCT00398216
- Testing
- DU176b - action is the prevention of venous thromboembolism by the use of a Factor Xa inhibitor
- Where
- 29 sites in United States, Canada and 5 more
- Volunteers
- 903 people
- Sponsor
- Daiichi Sankyo
Pulmonary Embolism, Venous Thrombosis
Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement
PEPPER is a randomized study comparing the three most commonly used anticoagulants in North America in patients who have elected to undergo primary or revision hip or knee joint replacement surgery.
- Trial name
- PEPPER (NCT02810704)
- Testing
- Enteric Coated Aspirin, Warfarin, Rivaroxaban
- Where
- 32 sites in United States, Canada
- Volunteers
- 18,883 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Testing Implementation of Total Joint Replacement Rehabilitation Quality Indicator Toolkits
The goal of this feasibility study is to test the procedures for implementing quality indicator toolkits for hip and knee replacement rehabilitation in clinical settings.
- Trial name
- NCT06208553
- Testing
- QI toolkit implementation
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- University of British Columbia
Osteoarthritis
Efficacy of Intravenous Versus Topical Tranexamic Acid in Primary Total Hip Arthroplasty
Bleeding during and after total hip replacement surgery is a primary concern to the surgical and anaesthetic team. Tranexamic acid is a commonly-used drug that helps blood clotting and decreases surgical bleeding.
- Trial name
- TeACH-R (NCT02056444)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypotension, Orthostatic, Total Hip Replacement
Study on Baroreceptor Function in Relation to Orthostatic Blood Pressure Regulation After Hip Surgery
The purpose of this observational study is to evaluate the baroreceptor function in relation to surgical inflammation and orthostatic intolerance after elective hip arthroplasty.
- Trial name
- NCT01866787
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Primary Total Hip Arthroplasty
Opioid Free Anesthesia in Total Hip Arthroplasty
Total hip arthroplasty (THA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- OFATHA (NCT05072704)
- Testing
- Sufentanil, Dexmedetomidine
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CMC Ambroise Paré
Hip Arthroplasty Replacement
Comparison of Wear Between Two Dual-mobility Acetabular Cups in Patients Undergoing Total Hip Arthroplasty
In 2022, data from the UK's National Joint Registry (NJR) and the American Joint Replacement Registry (AJRR) indicated that Total Hip Replacement (THR) is the most commonly performed orthopaedic joint surgery.
- Trial name
- CUPUSURE (NCT07207005)
- Testing
- ECIMA CORIN, CORIN
- Where
- France
- Volunteers
- 96 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Developmental Dysplasia of the Hip
AI-assisted Preoperative Planning Technology for THA for DDH
In this study, the investigators retrospectively collected DDH case data of THA assisted by AI 3D planning and THA assisted by traditional planning.
- Trial name
- NCT05929105
- Testing
- artificial intelligence (AI)-assisted three-dimensional preoperative planning technology, X-ray film template for 2D planning
- Where
- China
- Volunteers
- 61 people
- Sponsor
- General Hospital of Ningxia Medical University
Arthroplasty, Replacement, Hip
Does Testosterone Therapy Improve Patient-Reported Outcomes in Age-Related Testosterone Deficient Patients Undergoing Total Hip Replacement: A Randomized-Controlled Trial
This randomized-controlled trial will study on the effect of testosterone therapy on patients undergoing total hip replacement. Subjects will be male patients > 50 years with testosterone deficiency undergoing total hip…
- Trial name
- NCT05722301
- Testing
- Testosterone Therapy, No Testosterone Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- American Hip Institute
Total Hip Replacement
Digital Healthcare App After Total Hip Arthroplasty
This study examines the effectiveness of rehabilitation after hip replacement surgery using a specialised app called Akina Cloud. Medical professionals at the Schulthess Clinic will provide detailed information about the study.
- Trial name
- NCT06409312
- Testing
- Akina Cloud
- Volunteers
- 20 people
- Sponsor
- Schulthess Klinik
Prosthesis-Related Infections
Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty
The primary purpose of this study is to compare the re-infection rates in patients undergoing 2-stage revision arthroplasty who receive additional oral antibiotic therapy to those patients who received in-hospital perioperative…
- Trial name
- NCT01760863
- Testing
- Oral Antibiotics
- Where
- 4 sites in United States
- Volunteers
- 185 people
- Sponsor
- Rush University Medical Center
Arthroplasty, Replacement, Hip
Use of Local Analgesia With Epinephrine During Total Hip Arthroplasty (THA)
The aim is to determine if the use of infiltration with an adrenalin solution in the operative field of Total Hip Arthroplasty (THA), allays a significant reduction of the cumulated volume of bleeding (pre and post operative)…
- Trial name
- NCT00980616
- Testing
- ropivacaine, physical serum and adrenalin
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
Femoral Neck Fractures, Undisplaced Fracture
Hips Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients (HipSTHeR)
A registerbased RCT will investigate whether arthroplasty can decrease the reoperation rate compared to internal fixation for patients with an undisplaced femoral neck fracture (Garden I-II).
- Trial name
- HipSTHeR (NCT03966716)
- Testing
- Arthroplasty, Internal Fixation
- Where
- 25 sites in Sweden
- Volunteers
- 1,440 people
- Sponsor
- Uppsala University
Osteoarthritis, Post-traumatic Arthritis
A Randomised Study to Compare Metal Ion Release and Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-Metal or a Metal-on-Metal Bearing
The purpose of this study is to monitor the performance and compare the metal ion release of two bearing combinations, ceramic-on-metal and metal-on-metal in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders, Avascular Necrosis
- Trial name
- NCT00873444
- Testing
- Pinnacle™ Acetabular System
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- DePuy International
Orthopedic Surgery, Total Hip Prosthesis
Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive and Psychomotor Functions in Output Post Interventional Room Monitoring - COGNIDES
The recovery of cognitive and psychomotor functions is best performed under anesthesia after desflurane when propofol in that obtaining a Aldrete score> 8/10 output of the allowing SSPI.
- Conditions
- Orthopedic Surgery, Total Hip Prosthesis, Total Knee Replacement
- Trial name
- Cognides (NCT02036736)
- Testing
- Intraoperative anesthetic strategy by Propofol, Intraoperative anesthetic strategy by Desflurane
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgery, Surgical Incision
Direct Superior Approach (DSA) vs Posterior Approach (PA) in THA
Total Hip Arthroplasty (THA) is a highly effective treatment for patients with symptomatic hip osteoarthritis. The surgical approach in THA is important as it influences postoperative clinical recovery, functional outcomes, and…
- Conditions
- Surgery, Surgical Incision, Patient Satisfaction
- Trial name
- NCT04191993
- Testing
- Total hip arthroplasty
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University College, London
Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL
This study aims to analyze the efficacy of intravenous tranexamic acid (TXA) in patients undergoing total hip arthroplasty (THA).
- Conditions
- Blood Loss, Surgical, Tranexamic Acid Adverse Reaction, Hip Replacement
- Trial name
- NCT03019198
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Brazil
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
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