Clinical trials: Hip Replacement, Total
Unilateral Primary Osteoarthritis of Hip
Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
The aim of this study is to investigate the clinical outcome of the two different, but widely used, surgical approaches (Posterior approach and Lateral approach) of primary total hip arthroplasty in patients diagnosed with…
- Trial name
- COMPALA (NCT01616667)
- Testing
- Total hip arthroplasty
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hip Arthropathy
Assessment of Safety and Performances of HYPE Stems Associated to a SERF Acetabular Cup in Hip Arthroplasty (2017-01-NH)
The use of cementless femoral stems is known to provide satisfactory long-term clinical results. Extensive and durable osseointegration of these implants has been reported in numerous series, despite the use of stems with…
- Trial name
- NCT05524350
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Societe dEtude, de Recherche et de Fabrication
Postoperative Analgesia After Unilateral Hip Arthroplasty
Efficacy and Safety of TRD205 Tablets for Postoperative Analgesia in Unilateral Total Hip Arthroplasty (Phase IIb)
This is a phase IIa, multicenter ,randomized, double-blind, Double-Dummy, Active- and placebo-controlled study designed to evaluate the efficacy, safety and kinetic characteristics of TRD205 tablets for postoperative analgesia…
- Trial name
- TRD205 (NCT07543796)
- Testing
- TRD205 Tablets, oral; 400 mg initial dose, then 200 mg q12h for 3 doses; total 4 doses, TRD205 Tablets, oral; 800 mg initial dose, then 400 mg q12h; total 4 doses, TRD205 Tablets, oral; 1200 mg initial dose, then 600 mg q12h; total 4 doses
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Tide Pharmaceutical Co., Ltd
Total Hip Arthroplasty (THA), Revision Hip Arthroplasty
Cementation of Cup and the Risk of Second Revision
Background: The fixation method of the acetabular component during the primary total hip arthroplasty (THA) affects the surgical techniques implemented in the revision surgery and may influence the risk of second revision.
- Trial name
- NCT06583382
- Volunteers
- 60,000 people
- Sponsor
- Bispebjerg Hospital
Hip Arthropathy, Postoperative Pain
Pericapsular Nerve Group Block for Total Hip Arthroplasty
Controlling pain after hip replacement surgery improves comfort and partient satisfaction. Pain after hip replacement has traditionally been managed using systemic pain medications including acetaminophen and non-steroidal…
- Trial name
- NCT04295408
- Testing
- Pericapsular nerve group block with saline solution, Pericapsular nerve group block with ropivacaine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Hip Replacement, Total, Osteonecrosis of Femoral Head
Ultra-Short Anatomic and Conventional Cementless Stems Cementless Stems in Patients Younger Than Fifty-Five Years Old
As clinical and radiographic performance of an ultra-short anatomic cementless stem have been investigated only two randomized controlled studies, well-designed trials should aim for a thorough comparison of the outcomes of…
- Conditions
- Hip Replacement, Total, Osteonecrosis of Femoral Head, Coxarthrosis
- Trial name
- NCT02338596
- Testing
- Total hip replacement
- Volunteers
- 111 people
- Sponsor
- Ewha Womans University
Total Hip Replacement System
Ceramic on Metal Total Hip Replacement System Multi-Center,Investigational Device Exemption Clinical Trial
The purpose of this study is to demonstrate non-inferiority of the Ceramic on Metal Total Hip when compared to a TRANSCEND® historical control group of patients with primary total hip replacement.
- Trial name
- COM (NCT00820443)
- Testing
- Ceramic on metal prosthesis
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- MicroPort Orthopedics Inc.
Total Hip Arthroplasty (THA), Kinesiophobia
Preoperative Video-Based Education in Total Hip Arthroplasty
This single-center, prospective, randomized controlled trial aims to evaluate the effect of preoperative video-based mobilization education on postoperative fear of movement (kinesiophobia), pain during first mobilization, and…
- Conditions
- Total Hip Arthroplasty (THA), Kinesiophobia, Postoperative Pain, Early Mobilization
- Trial name
- NCT07279974
- Testing
- Video-Based Mobilization Education, Standard Verbal Education
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Acibadem University
Regional Anesthesia
Perioperative Analgesia for Total Hip Arthroplasty
This study is comparing the effect of lumbar plexus block and fascia iliaca block with general anesthesia to provide perioperative pain control and compare their effects on hemodynamics
- Trial name
- NCT04670497
- Testing
- bupivacaine 0.5% with 1:200000 adrenaline
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Coxarthrosis
Comparison Between Anterior and Direct Lateral Approach in Total Hip Arthroplasty
In total hip arthroplasty several approaches can be used. The newly introduced minimally invasive anterior approach is supposed to cause less damage to tendons and muscles.
- Trial name
- NCT01578746
- Testing
- Direct lateral approach in total hip arthroplasty, Anterior approach
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Sorlandet Hospital HF
Hip Osteoarthritis
MOVE-HIP: Ceramic Hip Resurfacing Versus Total Hip Arthroplasty Using Activity Monitoring
MOVE-HIP is a pragmatic, multicenter randomized clinical trial comparing ceramic hip resurfacing arthroplasty with contemporary total hip arthroplasty in adults with symptomatic hip osteoarthritis who are considered clinically…
- Trial name
- MOVE-HIP (NCT07839403)
- Testing
- Ceramic-on-Ceramic Hip Resurfacing Arthroplasty, Contemporary Total Hip Arthroplasty
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Danderyd Hospital
Metastatic Cancer to the Hip
Fully Constrained Acetabular Liner vs. Dual Mobility Hip Joint in the Surgical Treatment of Metastatic Bone Disease of the Hip
The purpose of the current study is to investigate whether dual mobility liners are non-inferior til constrained liners regarding the post-operative hip joint dislocation risk following total hip replacement in patients with…
- Trial name
- NCT05461313
- Testing
- Constrained Liner, Dual Mobility
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Hip, Hip Arthritis
Influence of Femoral Head Size During Total Hip Arthroplasty on Gait
Total hip replacement (THR) is being considered as one of the most effective medical procedures. Since its introduction, there was a worldwide debate over proper implant selection in terms of size, bearing type and shape.
- Conditions
- Osteoarthritis, Hip, Hip Arthritis, Gait, Frontal
- Trial name
- NCT04521842
- Testing
- Total hip replacement
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Warsaw
Hip Osteoarthritis
Regression Discontinuity Design Search for Differences in Mortality and Revision for Fixation Type of THA
The goal of this study is to apply the regression discontinuity design (RD) methodology on arthroplasty registry data. The investigators aim to use an age-based cut-off for fixation type choice and estimate the causal effect of…
- Trial name
- NCT05108155
- Testing
- Cemented THA, Unemented THA
- Where
- Netherlands
- Volunteers
- 43,789 people
- Sponsor
- Leiden University Medical Center
Lower Limb Arthroplasty Under Chloroprocaine Spinal Anesthesia
Intrathecal Chloroprocaine for Lower Limb Arthroplasty
This study evaluates the perioperative course in adult patients undergoing total or partial knee arthroplasty, or total hip arthroplasty under chloroprocaine spinal anesthesia.
- Trial name
- NCT05365074
- Testing
- Chloroprocaine Injection
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Hôpital de la Croix-Rousse
Venous Thromboembolism
Dabigatran Etexilate Compared With Enoxaparin in Prevention of Venous Thromboembolism (VTE) Following Total Hip Arthroplasty
The primary objective of the trial is to demonstrate non-inferiority of 220 mg oral dabigatran etexilate compared to 40 mg subcutaneous enoxaparin administered once daily.
- Trial name
- NCT00657150
- Testing
- Enoxaparin, Dabigatran etexilate
- Where
- 108 sites in United States, Australia and 17 more
- Volunteers
- 2,055 people
- Sponsor
- Boehringer Ingelheim
Total Hip Arthroplasty
Deep Posterior Post Gluteal Compartment Block in Total Hip Arthroplasty: Feasability and Safety
This study aims to evaluate the effectiveness of a posterior hip capsule block performed in addition to a PENG (Pericapsular Nerve Group) block for patients undergoing hip arthroplasty.
- Trial name
- ANATH (NCT06896591)
- Testing
- Deep posterior post gluteal nerve block
- Volunteers
- 35 people
- Sponsor
- Quincy Anesthésie
Femoral Neck Fractures
Dual Mobility Cups in Hip Fracture Patients
Our aim is to develop a strategy that reduces the risk of dislocations after total hip arthroplasty surgery performed due to femoral neck fracture.
- Trial name
- DUALITY (NCT03909815)
- Testing
- Dual mobility cup, Standard cup
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 1,600 people
- Sponsor
- Uppsala University
Anemia
A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo to Reduce the Need for Blood Transfusions and Reduce the Occurrence of Severe Anemia During the Time Period Surrounding Total Hip Replacement Surgery
The purpose of this study is to evaluate the safety and effectiveness of two different dosing schedules of epoetin alfa versus placebo for decreasing the need for blood transfusions and preventing the occurrence of severe anemia…
- Trial name
- NCT00269958
- Testing
- epoetin alfa
- Volunteers
- 208 people
- Sponsor
- Janssen-Ortho Inc., Canada
Hip Arthroplasty
Efficacy of Proprioceptive Neuromuscular Facilitation Exercise Program in Total Hip Arthroplasty
This study was planned to investigate the effectiveness of usual care and additional proprioceptive neuromuscular facilitation exercise program in patients undergoing total hip arthroplasty surgery.
- Trial name
- NCT06009432
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muğla Sıtkı Koçman University
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