Clinical trials: Hip Replacement, Total
Pain, Postoperative
Quadratus Lumborum Block for Total Hip Arthroplasty
The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip…
- Trial name
- NCT05247255
- Testing
- Active Comparator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Revision Total Hip Arthroplasty (RTHA)
Efficacy of Preoperative Autologous Blood Donation and Tranexamic Acid in Revision Total Hip Arthroplasty
Sixty patients aged between 60 and 75 years old of both sex of ASA physical status I and II were included in this randomized study who were divided into the study group of 30 patients who had been transfused autologous blood and…
- Trial name
- NCT02747615
- Testing
- transfused pre-operatively donated autologous blood., intravenous tranexamic acid (TXA) infusion, transfused only allogeneic blood.
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Localized Primary Osteoarthritis of Both Hips (Diagnosis), Osteoarthritis, Hip
Effect of Preoperative Intravenous Dexamethasone on Postoperative Pain After Primary Total Hip Arthroplasty
To compare the effects of preoperative intravenous Dexamethasone between 10 mg and 40 mg with placebo on Postoperative Pain After Primary Total Hip Arthroplasty
- Trial name
- NCT03542617
- Testing
- Dexamethasone, Normal Saline Solution
- Where
- Thailand
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
THA, Prosthesis
A Prospective Multicenter Clinical Study on the Efficacy and Safety of the Zirconia Ceramic Hip Joint Prosthesis System After Its Market Launch
This study adopted a prospective, multi-center, single-group target value trial design to evaluate the safety and efficacy of the hip joint prosthesis system produced by Beijing Anshou Technology Co., Ltd.
- Trial name
- NCT07382050
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Peking University Third Hospital
Post-operative Pain
Effect of Local Infiltration Analgesia in Total Hip Arthroplasty
The purpose of the study is to compare the effects of per-operative local infiltration analgesia with ropivacaine 0,2 % (150 ML) versus placebo on acute postoperative pain intensity after total hip arthroplasty.
- Trial name
- NCT00968955
- Testing
- Ropivacaine
- Where
- 2 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Infection of Total Hip Joint Prosthesis
Orthopedic Digital Planning for Total Hip Arthroplasties
Preoperative planning has been carried out to allow for response preparedness . A layer technique is usually used with standard radiography .The investigators have a record of routine preoperative radiographs by standard…
- Trial name
- ORTHOPLAN (NCT02842684)
- Testing
- TraumaCad software
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Toulouse
Osteoarthritis, Avascular Necrosis
Trilogy AB Acetabular Hip System Post Approval Study
This is a post-approval study with prospective enrollment in the United States and a retrospective enrollment outside the United States to obtain functional, quality of life and radiographic data, which will facilitate assessment…
- Conditions
- Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia, Traumatic Arthritis
- Trial name
- NCT00715026
- Testing
- Trilogy AB Acetabular Hip Implant System
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Zimmer Biomet
Prosthesis-Related Infections, Hip Prosthesis Infection
Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy.
It is not known in the literature how much sonication affects the patient's treatment. Another important issue is that the place of this method in diagnosis is not clear.
- Conditions
- Prosthesis-Related Infections, Hip Prosthesis Infection, Joint Infection, Biofilm
- Trial name
- NCT04304885
- Testing
- Sonication method
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Hip Osteoarthritis
Minimal Invasive Surgery in Total Hip Arthroplasty Patients; Strength, Functionality and Post Operative Complications
The aim of the present study is to explore the most efficient surgical approach in total hip replacement in short and long term when concerning strength, functionality and postoperative complications.
- Trial name
- NCT01959360
- Testing
- Direct lateral, minimal invasive, modified minimal invasive
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Norwegian University of Science and Technology
Primary Total Hip Arthroplasty, Primary Total Hip Replacement
Comparing Dual-mobility Cups Versus Unipolar Cups for Unselected Primary Total Hip Arthroplasty by Direct Anterior Approach
THA comprises the replacement of the damaged bone and cartilage with prosthetic components. The proximal end of the femur is replaced with a stem and ball/head, while the acetabulum is most commonly replaced with a unipolar cup…
- Trial name
- DUALSIM-THA (NCT07464665)
- Testing
- Primary total hip arthroplasty using dual-mobility cup, Primary total hip arthroplasty using unipolar cup
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Elsan
Osteoarthritis
A Randomized Controlled Trial of Long Versus Short Wait For Primary Total Hip and Knee Arthroplasty
The primary research question is: Does expedited hip and knee replacement result in improved lower-extremity function at 36 months post randomization as measured by the Western Ontario McMaster Universities Osteoarthritis Index…
- Trial name
- NCT00138892
- Testing
- Waiting time (access time to Total joint replacement)
- Where
- Canada
- Volunteers
- 236 people
- Sponsor
- University of British Columbia
Total Knee-replacement, Total Hip-replacement
Clinical Trial for Fibrin Sealant in Knee Surgery
Thermogenesis is a company that sells a machine for the production of fibrin sealant of single donor plasma, the CryoSeal Fibrin Sealant System (CS-1). Fibrin sealant consists of two components: cryoprecipitate and thrombin.
- Trial name
- NCT00440921
- Testing
- Single donor Allogenous Fibrin Sealant
- Sponsor
- Sanquin Research & Blood Bank Divisions
Avascular Necrosis, Osteoarthritis
Continuum™ Metal Bearing System in Total Hip Arthroplasty
The study is a multi-center, prospective, non-controlled, consecutive cohort post market surveillance study. The objective of this study is to obtain survival and outcome data on the Continuum Metal Bearing System in primary…
- Conditions
- Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Post-traumatic; Arthrosis
- Trial name
- NCT03382652
- Testing
- Metal-on-Metal Articulation
- Where
- 3 sites in United States, Finland
- Volunteers
- 83 people
- Sponsor
- Zimmer Biomet
Pain, Postoperative
Pain Profile and Pain Medication Use After THA and TKA
The over-prescription and overuse of opioid medications in the United States has recently been recognized as an epidemic. A new law in North Carolina (STOP Act) is aimed to limit opioid prescriptions following any surgical…
- Trial name
- NCT03714711
- Testing
- total hip arthroplasty, total knee arthroplasty
- Sponsor
- Duke University
Pain, Postoperative
Prediction of Pain in Total Hip Arthroplasty
In this consecutive, prospective cohort study the investigators evaluate if preoperative pain response upon heat stimulation is predictive for acute and subacute postoperative pain after total hip arthroplasty.
- Trial name
- NCT01324375
- Testing
- heat pain test (Modular Sensory Analyzer, Somedic AB, Horby, Sweden).
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Hvidovre University Hospital
Venous Thromboembolism, Venous Thromboses
inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT
After hip or knee replacement all patients receive a standardized treatment with blood thinners, this medication is called thrombosis prophylaxis.
- Conditions
- Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- DISTINCT (NCT06581965)
- Testing
- Short duration prophylaxis, Higher intensity and longer duration prophylaxis, Control
- Where
- 13 sites in Netherlands
- Volunteers
- 10,078 people
- Sponsor
- Leiden University Medical Center
Total Hip Replacement
Study of Total Hip Arthroplasty Using Radlink Surgical Positioning Software
This is a prospective, randomized study of total hip arthroplasty with and without the use of Radlink surgical positioning software.
- Trial name
- NCT02536573
- Testing
- Radlink Surgical Positioning Software
- Volunteers
- 200 people
- Sponsor
- Anderson Orthopaedic Research Institute
Hip Fractures (ICD-10 72.01-72.2), Postoperative Pain Management After Total Hip Arthroplasty
Effect of Preoperative PENG Block on Spinal Anesthesia Positioning and Postoperative Analgesia in Hip Fracture Surgery
Hip fractures are among the most common orthopedic traumas, particularly in elderly patients, and are usually associated with significant pain during positioning for spinal anesthesia.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Postoperative Pain Management After Total Hip Arthroplasty, Elderly Patients, Regional Anesthesia
- Trial name
- PENG-SPINE (NCT07194356)
- Testing
- Pericapsular nerve group (PENG) block, Standard Spinal Anesthesia (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Arthritis of Hip
Ultrasound-guided Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Total Hip Arthroplasty
Total hip replacement (THR) is a common and major surgical procedure performed in elderly patients with significant comorbidities.
- Trial name
- HIPFIB (NCT03069183)
- Testing
- 0.5% Ropivacaine, Normal saline
- Where
- Canada
- Volunteers
- 133 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Acute, Hip Arthropathy
Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty
Multimodal pain management is essential for recovery after surgery, aiming to target different pain mechanisms to minimize opioid usage and opioid-related adverse effects.
- Conditions
- Pain, Acute, Hip Arthropathy, Analgesia, Postoperative Pain
- Trial name
- RECIPE (NCT04123873)
- Testing
- Paracetamol, Ibuprofen, Dexamethasone
- Where
- 7 sites in Denmark
- Volunteers
- 1,060 people
- Sponsor
- Naestved Hospital
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