Clinical trials: Hip Replacement Arthroplasty
Primary Osteoarthritis Requiring Total Hip Replacement
Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA)
Postoperative pain following total hip arthroplasty (THA) (1) is often considered moderate to severe and can therefore influence the postoperative course of event and result in delayed postoperative mobilization and prolonged…
- Trial name
- HÖFTPLASTIK (NCT01281891)
- Testing
- LIA, I/T morphine
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Örebro County
Opioid Use, Pain, Post Operative
A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery
Opioid addiction in post-operative patients is recognized but not fully understood; therefore, in order to address this growing crisis, it is essential to explore alternative approaches to managing pain and apply them to the…
- Trial name
- NCT05252858
- Testing
- nCAP Signal Relief Patch, Standard of Care
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Jacques E. Chelly
Decision Making, Shared, Arthroplasty, Replacement, Knee
RCT Measuring the Effect of the ERVIN Software
The randomised clinical trial investigates the effect of using a clinical decision support system (CDSS) aiming to provide the patients and surgeons with greater transparency concerning the obtainable changes in function and…
- Conditions
- Decision Making, Shared, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip, Osteoarthritis, Knee
- Trial name
- NCT04332055
- Testing
- ERVIN
- Where
- Denmark
- Volunteers
- 223 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Expectations, Satisfaction and Quality of Life in Total Hip Arthroplasty
The goals of this study are to identify predictors of improvement in quality of life and satisfaction with total hip arthroplasty three to five years after surgery.
- Trial name
- NCT00197990
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Hospital for Special Surgery, New York
Hip Replacement Arthroplasty
Determination of Metal Ion Serum Levels and Cytokines in Total Hip Replacement
The goal of the study is the analysis of metal ion serum concentrations and of the cytokine production in the blood of patients with a conventional cementless total hip replacement.
- Trial name
- NCT01394744
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Pain, Postoperative
Erector Spinae Block Versus PENG Block for Hip Replacement
THR (Total Hip Replacement) can be very painful and regional anesthesia is very effective in reducing postoperative pain. Erector Spinae Plane Block (ESPB) and PENG (pericapsular nerve group block) are alternative approaches to…
- Trial name
- PENGESP (NCT05796804)
- Testing
- ERECTOR SPINAE PLANE BLOCK, Peng block + lateral femoral cutaneous nerve block, spinal anesthesia
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Papa Giovanni XXIII Hospital
Anemia, Arthroplasty, Replacement, Hip
Incidence and Reasons for Preoperative Anemia in Elective Lower Joint Arthroplasty
Preoperative anemia is an independent risk factor for the need for allogeneic transfusion during surgery and increased postoperative morbidity. Treatment of preoperative anemia is recommended.
- Conditions
- Anemia, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT02385409
- Where
- Denmark
- Volunteers
- 900 people
- Sponsor
- Oeivind Jans
Arthroplasty, Replacement, Hip
Effect of Cuff Pressure During Operation on Postoperative Sore Throat
When general anesthesia is performed for surgery, tracheal intubation is performed. In order to ventilate after performing tracheal intubation, air is injected into the cuff attached to the tube to fill the gap between the…
- Trial name
- NCT04247360
- Testing
- cuff pressure
- Volunteers
- 138 people
- Sponsor
- Keimyung University Dongsan Medical Center
Coxarthrosis, Arthroplasties Hip Replacement
Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty
The primary aim of this study is to test if etoricoxib decreases the perioperative blood loss compared to diclofenac. Secondary questions to be explored are: Does etoricoxib prevent Heterotopic ossification after Total Hip…
- Conditions
- Coxarthrosis, Arthroplasties Hip Replacement, Perioperative Blood Loss
- Trial name
- NCT01229774
- Testing
- Etoricoxib, Diclofenac
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Regensburg
Total Hip Replacement Surgery, Postoperative Pain
Effectiveness of PENG Block Combined to LFCN Block on the Quality of Recovery After Total Hip Replacement
The main objective of this study is to evaluate the effectiveness of the association of PENG and LFCN blocks on the quality of recovery 24 hours after total hip replacement surgery.
- Trial name
- PENG (NCT04245280)
- Testing
- Ropivacaine 0.5% Injectable Solution, Saline Solution
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Arthroplasty, Replacement
Effects of Early Home-based Strength and Sensory-motor Training After THA on Functional Outcome and Patient Satisfaction
A prospective multicentre randomised clinical trial of 250 selected patients with THA, who will be randomly assigned to intervention (IG) or control group (CG).
- Conditions
- Arthroplasty, Replacement, Hip, Strength Training
- Trial name
- NCT04061993
- Testing
- Strength and Sensory-Motor Training, Current Standard Physiotherapy
- Where
- 2 sites in Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Valdoltra Orthopedic Hospital
Arthritis
Sexual Function Questionnaire Total Hip Replacement
Non-commercial trial 2 Centres involved: University Hospital Southampton and Spire Southampton Expected number of eligible participants available per year: 100, (95% expected to agree to participation) The study will recruit…
- Trial name
- NCT02290652
- Testing
- Prospective - Factors affecting sexual function pre-THR, Retrospective- Factors affecting sexual function post-THR
- Where
- 2 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Patient Readmission, Arthroplasty, Replacement, Knee
A Study of the Effect of a Nurse Navigator Program on High Risk Patients
The purpose of this study is to examine if educational intervention in high risk patients can lead to decreased hospital readmissions when compared to patients who are not in the intervention program.
- Conditions
- Patient Readmission, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip, Heart Failure
- Trial name
- NCT05592847
- Testing
- Nurse Navigator Program
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mayo Clinic
Total Hip Replacement, Wound Complication
Hip DAA Closure Techniques
This study aims to analyze the difference in rates of wound complications using two different closure techniques in Direct anterior approach for primary total hip replacement.
- Trial name
- NCT06006572
- Testing
- wound closure subcuticular running stitch using 3-0 monocryl suture without skin adhesive, wound closure subcuticular running stitch using 3-0 monocryl suture with two layers of skin adhesive
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Arthroplasty, Replacement, Hip, Osteoarthritis, Hip
Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement.
Total hip replacement is the most successful treatment modern healthcare can offer patients to regain quality of life. Periprosthetic joint infection (PJI) is the most common and devastating complication after total hip…
- Conditions
- Arthroplasty, Replacement, Hip, Osteoarthritis, Hip, Antibiotic Resistant Infection, Prosthetic Joint Infection
- Trial name
- ABOGRAFT (NCT05169229)
- Testing
- Vancomycin + Tobramycin, Saline
- Where
- Sweden
- Volunteers
- 1,100 people
- Sponsor
- University Hospital, Linkoeping
Hip Osteoarthritis
OXINIUM◊ DH Total Hip Arthroplasty Pivotal Study
The purpose of this study is to monitor safety of the participants implanted with the OXINIUM◊ DH Hip System up to 10-years post-implantation
- Trial name
- NCT02353377
- Testing
- OXINIUM DH Hip System, BIOLOX◊
- Volunteers
- 413 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis
Overcoming TWEAK Signaling to Restore Muscle and Mobility After Joint Replacement
This single-blind, randomized, controlled trial is designed to test the effect of an intensive, 16 week exercise rehabilitation program (progressive resistance training + functional mobility training) vs.
- Trial name
- TWEAK (NCT02628795)
- Testing
- PRT + FM, Usual Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Total Hip Replacement, Thromboelastometry
Impact of Surgical Injury on Haemostatic Tests in Patients Undergoing Total Hip Replacement With Subgroup Analysis of Patients With Neoplasm
Total hip replacement (THR) is associated with extensive tissue injury and considerable blood loss that can be complicated by hyperfibrinolysis with an increased need for blood transfusion.
- Conditions
- Total Hip Replacement, Thromboelastometry, Bone Neoplasm of Hip
- Trial name
- I-SIGHT-THR (NCT04442373)
- Testing
- Rotational thromboelastometry
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Total Hip Replacement
Comparative Effects of Weight Bearing and Non-weight Bearing Exercises in Patients With Total Hip Replacement
to compare the effects of weight bearing and non-weight bearing exercises on pain, range of motion and disability in patients with total hip replacement
- Trial name
- NCT05375565
- Testing
- weight bearing exercises, non weight bearing exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Orthopedic Procedure
Implementation of Fast-track Surgery Program for Total Hip and Knee Replacement and the Evaluation of the Risks and Benefits for the Patient
Implementation of Fast-track surgery for total hip replacement and total knee replacement and evaluation of the risks and benefits for the patients.
- Trial name
- NCT03028779
- Testing
- Fast-track Total Hip and knee arthroplasty
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital