Clinical trials: Hip Surgeries
Coagulation; Intravascular, Rotational Thromboelastometry
The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery
Total hip arthroplasty (THA) is associated with blood loss ranging from 300 to 2000 mL. Tranexamic acid (TXA) is frequently administered prophylactically during this procedure to reduce blood loss by inhibiting fibrinolysis or by…
- Conditions
- Coagulation; Intravascular, Rotational Thromboelastometry, Fibrinolysis; Hemorrhage, Tranexamic Acid
- Trial name
- NCT03897621
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Prosthesis-related Infections
European Prosthetic Joint Infection Cohort Study- Hip, Knee and Shoulder Prosthetic Joint Infection
The purpose of the study is to compare different approaches for the treatment of prosthetic joint revisions and to optimize the outcomes in patients with prosthetic joint infections (PJI) by improving the treatment concept of PJI.
- Trial name
- EPJIC (NCT02424903)
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Pro-Implant Foundation
Hip Surgery Corrective, Knee Injuries
Prospective, Randomized Clinical Investigation of Two Different Postoperative Wound Dressings
The primary objective of this investigation is to evaluate if complications related to surgical wound are more common in the treatment group compared to the control group starting from operation day until last visit.
- Trial name
- MxBPo02 (NCT02653183)
- Testing
- Active Comparator: Aquacel Surgical, Experimental: Mepilex Border Post-Op
- Where
- 3 sites in Belgium, Sweden
- Volunteers
- 118 people
- Sponsor
- Molnlycke Health Care AB
Surgical Site Infection, Hip Fractures
Wound Contamination During Orthopaedic Surgery
In the present study we will compare bacteriological findings and the incidence of SSI in relation to laminar airflow (LAF) ventilated ORs, conventional (also called displacement or mixed) ventilated ORs and conventional…
- Conditions
- Surgical Site Infection, Hip Fractures, Orthopedic Disorder, Implant Infection
- Trial name
- Clean Care (NCT04676841)
- Testing
- Conventional ventilation + instrumental tables with integrated laminar airflow, Conventional ventilation + standard instrumental tables, Laminar airflow ventilation + standard instrumental tables
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Vastra Gotaland Region
Revision Surgery of Total Hip Arthroplasty
Effect of Denosumab on Inflammatory Osteolytic Lesion Activity in Total Hip Arthroplasty
Although hip replacement surgery is a successful way of dealing with the pain and immobility caused by hip arthritis, 10% of the hip replacements carried out in the UK fail within 10 years.
- Trial name
- NCT01358669
- Testing
- Denosumab
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Total Hip Replacement
Effect of Steroids on Thrombosis (Blood Clot Formation) and Inflammation in Patients Undergoing Hip Surgery
Studies have shown that surgery causes some reactions in your body consistent with inflammation. When the inflammation is extensive, it may affect different parts of the body including the lungs.
- Trial name
- NCT01782859
- Testing
- Prednisone, Hydrocortisone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthrosis Patients With Total Hip Arthroplasty
Thigh Swelling, Hip-muscle Strength, and Functional Performance Following Total Hip Arthroplasty
By this study the investigators wish to (1) quantify hip strength and functional-performance deficits at discharge after fast-track total hip arthroplasty (THA), and (2) investigate if changes in thigh circumferences, or hip pain…
- Trial name
- THA (NCT01246674)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Hvidovre University Hospital
Hip Fractures, Hip Arthropathy
Optimizing Cerebral Autoregulation During Surgery
The purpose of this study is to conduct a pilot trial to determine the feasibility, safety, and potential efficacy of targeting mean arterial blood pressure (MAP) within the limits of cerebral autoregulation during surgery…
- Conditions
- Hip Fractures, Hip Arthropathy, Surgery, Delirium
- Trial name
- NCT05308290
- Testing
- Blood pressure management according to cerebral autoregulation, Blood pressure management according to usual care
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Johns Hopkins University
Ultrasound Guided L1,L2 Paravertebral Block
Effect of Ultrasound Guided L1,L2 Paravertebral Block in Decrease the Requirements for Hypotensive Drugs During General Anesthesia in Patients Undergoing Hip Surgeries.
The paravertebral block (PVB) is a block of the mixed nerve soon after it exits the intervertebral foramen.(2) It provides intense unilateral analgesia of long duration and has become the primary anesthetic for many…
- Trial name
- NCT03422354
- Testing
- Ultrasound guided PVB with General Aneasthesia, Ultrasound, Paravertebral block
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sacral Erector Block Versus Pericapsular Block Versus Lumber Plexus Block
The Analgesic Effect of Ultrasound-guided Sacral Erector Spinae, Pericapsular Nerve Block and Lumber Plexus Block for Pain Relief for Hip Surgery: Randomized Controlled Study
The aim of this study to evaluate the effect of The analgesic effect of Ultrasound-guided Sacral erector spinae, Pericapsular nerve block and Lumber Plexus block for pain relief after hip surgery.
- Trial name
- NCT06842342
- Testing
- Lumber plexus block, Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), PENG Block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Hypotension, Orthostatic, Total Hip Replacement
Study on Baroreceptor Function in Relation to Orthostatic Blood Pressure Regulation After Hip Surgery
The purpose of this observational study is to evaluate the baroreceptor function in relation to surgical inflammation and orthostatic intolerance after elective hip arthroplasty.
- Trial name
- NCT01866787
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Hip, Rheumatoid Arthritis
Acetabular Shell Positioning Using Patient Specific Instruments
The proposed study is a double-blinded randomized controlled trial comparing patient specific instruments with solely standardized instruments and pre-operative planning used for the placement of the acetabular cup prosthesis…
- Conditions
- Osteoarthritis, Hip, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT01791738
- Testing
- Acetabular positioning system
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Cleveland Clinic
PENG Block
Effectiveness Of The Pericapsular Nerve Group (PENG) Block In Hip Surgery
The target population of hip surgery is usually the elderly patients with systemic comorbidity. Especially hip fractures are common in society and cause high morbidity and mortality for geriatric patients .
- Trial name
- NCT05997940
- Testing
- PENG block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Aydin Adnan Menderes University
Hip Fracture
Thromboelastography (TEG) and Clopidogrel Withdrawal Time in Elderly Patients With Hip Fracture
In the elderly patients with hip fracture, some often take antiplatelet drugs such as clopidogrel due to the ischemic cardiovascular or cerebrovascular diseases.
- Trial name
- NCT04165538
- Testing
- Thrombelastograph and surgical timing
- Volunteers
- 140 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Thrombosis, Postoperative Complications
Epidemiology Study in Major Orthopaedic Surgery
The purpose of this study is to: Create a database including a description of the patient population that undergoes total hip replacement with special emphasis on orthopedic and cardiovascular complications and the quality of…
- Conditions
- Thrombosis, Postoperative Complications, Quality of Life
- Trial name
- NCT00159185
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Hoersholm Hospital
Femur Fracture, Hip Surgery
Pericapsular Nerve Group (PENG) Block on Pain During Participant Positioning for Spinal Anesthesia in Hip Fracture Surgery
Hip fracture surgery is a common orthopedic procedure, especially in elderly patients. These fractures are quite common in adults over the age of 65, and the one-year mortality rate ranges from 12% to 37%.
- Trial name
- NCT06813755
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University
Postoperative Pain
Evaluation of PENG Block in Terms of Block Time and Postoperative Pain
Hip fracture is a common orthopedic emergency in the elderly and causes significant morbidity and is associated with mortality. In most patients, surgical reduction and fixation is the definitive treatment.
- Trial name
- NCT06132308
- Testing
- PENG Block with 0.25% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Pain, Analgesia
PENG Block Combined to Wound Infiltration for Hip Replacement
This study analyze the effect of Pericapsular Nerve Group (PENG) Block combined to wound infiltration for analgesia after elective hip replacement.
- Conditions
- Postoperative Pain, Analgesia, Hip Arthropathy, Acute Pain
- Trial name
- NCT04306133
- Testing
- PENG block, Wound Infiltration
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Acute Kidney Injury
PREdicting RENAL Injury In Patient After Hip Fracture Surgery
To determine whether MALDI, a type of Mass-Spectometry, can use protein pattern detection within urine to predict postoperative (after an operation) kidney damage in adults who have undergone emergency hip fracture surgery?
- Trial name
- PRE-RENAL (NCT03049150)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Fracture of Hip
InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery
The goal of this pilot, patient blinded randomized trial is to develop a mechanistic understanding of gait following fixation of unstable intertrochanteric hip fractures and return to function and pain control.
- Trial name
- NCT06024304
- Testing
- Synthes TFNA, Trigen InterTAN
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Paul E. Matuszewski