Clinical trials: Hip and Knee Replacement Surgeries
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Study Measuring the Effects of Patient Data for Total Hip and Total Knee Arthroplasty Patients Using an APP Based Sensor for Home Exercise Performance Before and After Operation
Multicenter, Prospective, Randomized, Comparative Study Measuring the Effects on Clinical Outcomes, Patient Satisfaction, Costs and Benefits of Combined Pre-, Intra- and Postoperative Patient Data for THA and TKA Patients Using…
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Clinical Outcome, Patient Satisfaction
- Trial name
- ORTHOPATH (NCT05182320)
- Testing
- OrthoPath, Control
- Where
- 2 sites in Germany
- Sponsor
- Aesculap AG
Hip and Knee Replacement Surgeries
California Joint Replacement Registry
The California Joint Replacement Registry (CJRR) was created to meet the need for comprehensive, scientific assessment of devices, treatment protocols, surgical approaches, and patient factors influencing the results of hip and…
- Trial name
- CJRR (NCT01787812)
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- California Joint Replacement Registry
Knee Arthropathy, Hip Injuries
A Study to Evaluate Virtual Reality As Adjunct to Anesthesia During Orthopedic Surgery
The purpose of this study is to obtain feedback from patients and orthopedic surgeons who agree to use virtual reality (VR ) as an adjunct to standard of care in orthopedic cases under regional or central neuraxial nerve block.
- Trial name
- NCT05112302
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Stress
The SENSE Study: Surgical ENvironment Stress Evaluation
Surgical procedures such as total hip and knee arthroplasty require a complex set of physical and cognitive skills, expert execution, and inevitably place a high stress load on the surgeon.
- Trial name
- SENSE (NCT07506330)
- Testing
- total joint arthroplasty
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University College, London
Artificial Intelligence (AI), Machine Learning
Development and Pre-validation of a Machine Learning-based Prediction Algorithm for Early Functional Recovery in Patients Undergoing Hip and Knee Replacement Surgery
The goal of this observational study is to develop and pre-validate a machine learning algorithm to predict early recovery of mobility in patients undergoing hip or knee joint replacement surgery.
- Conditions
- Artificial Intelligence (AI), Machine Learning, Joint Replacement, Predictive Model
- Trial name
- FISIO_IA (NCT07333560)
- Testing
- Predictive Model for Early Mobility Recovery and Length of Stay
- Where
- 2 sites in Italy
- Volunteers
- 943 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteo Arthritis Knee and Hip, Osteo Arthritis
General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are common operations used to treat severe joint disease, most often caused by osteoarthritis.
- Conditions
- Osteo Arthritis Knee and Hip, Osteo Arthritis, Inflammatory Joint Disease (IJD)
- Trial name
- GASPS (NCT07334132)
- Testing
- General Anaesthesia, Spinal Anesthesia (bupivacaine)
- Volunteers
- 600 people
- Sponsor
- Region Örebro County
Arthroplasties, Hip Replacement, Arthroplasties, Knee Replacement
The Effect of A New Perioperative Practice Model on Patient, Nursing And Organisational Outcomes
The aim of the study is to improve the surgical patients' care process. The objective is to explore the effect of a new perioperative practice model on 1) patient outcomes (satisfaction, surgery-related anxiety and quality of…
- Trial name
- NCT02906033
- Testing
- New perioperative practice model
- Where
- Finland
- Volunteers
- 517 people
- Sponsor
- Hospital District of Helsinki and Uusimaa
Diabetes Mellitus, Type 2, Arthroplasty, Replacement, Hip
CGM Monitoring in T2DM Patients Undergoing Orthopaedic Replacement Surgery
The purpose of this study is to analyze the efficacy and accuracy of real-time continuous glucose monitoring devices (rtCGM) in patients with Type 2 diabetes undergoing inpatient elective hip or knee surgery in the pre-, peri…
- Conditions
- Diabetes Mellitus, Type 2, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT05666479
- Testing
- Dexcom G6 Pro Continuous Glucose Monitor (CGM)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stony Brook University
Femoral Fractures, Pelvic Fractures
Tactile Incentiviser Improves Partial Weight Bearing After Lower-Limb Surgery
Background: After lower-limb surgery, many patients are instructed to walk with only a fraction of their body weight on the operated leg (partial weight bearing).
- Conditions
- Femoral Fractures, Pelvic Fractures, Hip Fractures (ICD-10 72.01-72.2), Hip Arthroplasty
- Trial name
- NCT06989554
- Testing
- mechanical feedback insole, Standard physiotherapy without feedback device
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Università degli Studi dell'Insubria
Knee Osteoarthritis, Hip Osteoarthritis
Daycase Hip and Knee Arthroplasty in Møre and Romsdal Trial
The DART Study is a prospective, multicentre observational cohort study evaluating day-case pathways for patients undergoing primary total hip arthroplasty, total knee arthroplasty, or unicompartmental knee arthroplasty at three…
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Osteonecrosis, Osteoarthritis
- Trial name
- DART (NCT07834034)
- Testing
- Total Hip Arthroplasty, Total Knee Arthroplasty, Unicondylar knee artrhoplasty
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Helse Møre og Romsdal HF
Total Hip Replacement, Total Knee Replacement
Dressing-related Experiences and Surgical Site Self-care in Hip and Knee Replacement: an Observational Cohort Study
The goal of this prospective observational cohort study is to investigate dressing-related experiences and surgical site self-care in patients who are undergoing a total hip or knee replacement.
- Trial name
- DRESS-X (NCT07471243)
- Testing
- Wound Dressing Material
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Bournemouth University
Joint Replacement Surgery
The Effect of a Psychosensory Therapy
This is a prospective study looking at the impact of psychosensory therapy and how it can diminish pain and consumption of pain medications.
- Trial name
- NCT02765932
- Testing
- Dummy Movements, Psychosensory Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Hip Fractures, Knee Arthroplasty
Continuous Spinal Anesthesia Versus Combined Spinal Epidural Block
In major orthopaedic surgery of the lower extremities both continuous spinal anesthesia (CSA) and combined spinal epidural anesthesia (CSE) are safe and reliable anaesthesia methods.
- Conditions
- Hip Fractures, Knee Arthroplasty, Femur Fracture
- Trial name
- Spinocath (NCT00616044)
- Testing
- continuous spinal anesthesia, Spinocath a catheter for continuous spinal anesthesia, combined spinal epidural anesthesia
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Sao Jose do Rio Preto Medical School
Prophylaxis, Thromboembolism, Venous, Total Knee Replacement
Study to Observe Safety of Xarelto in VTE Prophlylaxis After Elective TKR (Total Knee Replacement) or THR (Total Hip Replacement)
The primary objective of this study is to evaluate the safety of Xarelto in the prophylaxis of VTE in Indian patients undergoing elective TKR/THR
- Conditions
- Prophylaxis, Thromboembolism, Venous, Total Knee Replacement, Total Hip Replacement
- Trial name
- XYRIS (NCT01523418)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Sponsor
- Bayer
Orthopedic Surgery, Total Hip Prosthesis
Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive and Psychomotor Functions in Output Post Interventional Room Monitoring - COGNIDES
The recovery of cognitive and psychomotor functions is best performed under anesthesia after desflurane when propofol in that obtaining a Aldrete score> 8/10 output of the allowing SSPI.
- Conditions
- Orthopedic Surgery, Total Hip Prosthesis, Total Knee Replacement
- Trial name
- Cognides (NCT02036736)
- Testing
- Intraoperative anesthetic strategy by Propofol, Intraoperative anesthetic strategy by Desflurane
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis
Pain Expectations in Subjects With Osteoarthritis
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat…
- Trial name
- NCT02155257
- Testing
- Modafinil, Gabapentin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Russian Non-Interventional Study on Compliance of Venous Thromboembolism (VTE)
This is a local, prospective, multicenter, non-interventional, observational study. Primary objective is to describe how in "real life" thromboprophylaxis is carried out after the discharge from a hospital in the patients who…
- Trial name
- SOPRANO (NCT01444586)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Russia
- Volunteers
- 2,293 people
- Sponsor
- Bayer
Osteoarthritis, Infection
Prospective, Randomized Study Evaluating The Efficacy of Chlorhexidine Gluconate Impregnated No-Rinse Cloths.
Subjects in the study were randomized to a treatment group using Chlorhexidine cloths or a standard-of-care group who only had a bath with antibacterial soap and water.
- Trial name
- SAGE (NCT02469311)
- Testing
- chlorhexidine impregnated cloths, Standard of care bathing with antibacterial soap and water
- Volunteers
- 539 people
- Sponsor
- LifeBridge Health
Osteoarthritis, Depression
Psychological, Sexually and Social Consequences of Osteoarthritis Treatment With THA or TKA and Joint Preserving Surgery
The project runs as a Ph.d. project at the Faculty of Health Sciences- University of Copenhagen. In Denmark the investigators operate around 16.000 artificial hips and knees yearly, mainly due to osteoarthritis.
- Conditions
- Osteoarthritis, Depression, Hip Dysplasia
- Trial name
- NCT01305759
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Hvidovre University Hospital
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Effects of Preoperative Education, and Follow-up Sessions of Patients With Total Hip and Knee Arthroplasty (ESIPPES)
The shortening of the length of stay implies rethinking the perioperative management (around the operative period), which precedes and immediately follows the operation, in order to ensure a good preparation of the patient and an…
- Trial name
- ESIPPES (NCT05452161)
- Testing
- Control group, Intervention group A, Intervention group B
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- Haute Ecole de Santé Vaud