Clinical trials: Hip and Knee Replacement Surgeries
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Hip Fracture, Osteoarthritis
Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery
The purpose of this study is to determine the effects of two postoperative interventions designed to preserve muscle protein after major hip or knee surgery.
- Conditions
- Hip Fracture, Osteoarthritis, Femur Head Necrosis
- Trial name
- NCT00393848
- Testing
- Essential amino acid supplement, Ketoconazole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arkansas
Surgical Wound
PICO 7 vs PICO 14 in Revision Hip and Revision Knee Surgery.
This is a single-site trial, and it has been designed to compare a revision hip cohort with a revision knee cohort. All consecutive eligible patients, under the care of participating Co-Investigator Orthopaedic Surgeons, are…
- Trial name
- NCT05389410
- Testing
- PICO 7, PICO 14
- Where
- United Kingdom
- Volunteers
- 164 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Orthopedic Procedure
Implementation of Fast-track Surgery Program for Total Hip and Knee Replacement and the Evaluation of the Risks and Benefits for the Patient
Implementation of Fast-track surgery for total hip replacement and total knee replacement and evaluation of the risks and benefits for the patients.
- Trial name
- NCT03028779
- Testing
- Fast-track Total Hip and knee arthroplasty
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty(Postoperative Pain)
Dose Dependent Effects of tDCS on Post-Operative Pain
The proper control of acute and chronic pain is one of the most important areas in health care. Despite the profound advances in neuroscience over the past 20 years, the investigators still largely use opiate narcotics, much as…
- Trial name
- tDCS-TKA (NCT02241967)
- Testing
- 4 Real sessions of Transcranial Direct Current Stimulation, 2 Real Sessions of Transcranial Direct Current Stimulation, 1 Real Session of Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
Arthropathy of Knee, Arthropathy of Hip
Results of the Application of the Clinical Pathway of Intensified Recovery Surgery for Adults in the Processes of Total Knee and Hip Replacement at the Maz Hospital
The investigators are going to study all the patients who have undergone surgery at the MAZ hospital from 2019 to the present for knee replacement and hip replacement.
- Trial name
- NCT05338255
- Where
- Spain
- Volunteers
- 534 people
- Sponsor
- Universidad de Zaragoza
Total Hip and Knee Arthroplasties
Teicoplanin Prophylaxis for Total Hip or Knee Arthroplasty
This is a prospective, open-label, randomized clinical trial where patients were administered prophylaxis for total hip or knee arthroplasty either with teicoplanin or with other antibiotics.
- Trial name
- NCT00719056
- Testing
- Teicoplanin, β-lactams or ciprofloxacin
- Where
- 3 sites in Greece
- Volunteers
- 616 people
- Sponsor
- University of Athens
Osteoarthritis
Out Patient Surgery for Total Knee and Hip Replacement and Unicompartmental Knee Replacement - a Feasibility Study
The purpose of this study is to evaluate feasibly of outpatient Total Knee Replacement, Total Hip Replacement and Unicompartmental Knee Replacement in a modern fast-track setup.
- Trial name
- NCT02544620
- Testing
- Does fulfil of discharge criteria on the day of the surgery, Does not fulfil of discharge criteria on the day of the surgery
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Kirill Gromov
Old Age, Knee Replacement Surgery
Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality
Sleep disturbances are prevalent in older patients with osteoarthrosis or fracture who are scheduled for knee or hip replacement surgery.
- Conditions
- Old Age, Knee Replacement Surgery, Hip Replacement Surgery, Dexmedetomidine
- Trial name
- NCT05950646
- Testing
- Dexmedetomidine, Esketamine, Normal saline
- Where
- 2 sites in China
- Volunteers
- 154 people
- Sponsor
- Peking University First Hospital
Orthopedic Surgery, Rehabilitation
Comparison of Telerehabilitation and Usual Rehabilitation After Knee or Hip Surgery
After knee or hip replacement surgery, rehabilitation helps patients regain mobility, improve muscle strength, and return to their daily activities.
- Trial name
- TELEARTHROPOST (NCT07902505)
- Testing
- Standard Inpatient Rehabilitation, Telerehabilitation
- Where
- France
- Volunteers
- 216 people
- Sponsor
- Centre Hospitalier de Valenciennes
Surgical Wound, Knee Arthroplasty
Skin Closure in Prosthetic Joint Surgery: Comparative Evaluation of the "Barbed Sutures and Skin Glue" Technique (Cica-Pro)
The choice of skin closure (staples vs. monofilament sutures vs. barbed sutures/adhesive) is critical for wound healing quality in prosthetic surgery (hip and knee).
- Conditions
- Surgical Wound, Knee Arthroplasty, Hip Arthroplasty
- Trial name
- Cica-Pro (NCT07749495)
- Testing
- primary knee replacement, Primary hip replacement.
- Volunteers
- 400 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Pulmonary Embolism
Prophylaxis Against DVTs After Primary Hip and Knee Replacement Surgery
The purpose of this research is to find a better way to prevent the post operative development of clots in the deep veins of the legs (also called Deep Vein Thrombosis or DVT).
- Trial name
- DVT (NCT00767559)
- Testing
- warfarin, Fondaparinux:
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- The New England Baptist Hospital
MYOCARD INFARCTUS, Non Cardiac Surgery
Myocardial Injury After Noncardiac Surgery (MINS) in Patients Undergoing Knee and Hip Arthroplasty
The aim of this study is to determine the incidence of myocardial injury after noncardiac surgery (MINS) in patients undergoing elective total knee or hip arthroplasty, and to identify the demographic, clinical, laboratory, and…
- Conditions
- MYOCARD INFARCTUS, Non Cardiac Surgery, ARTHROPLASTY, REPLACEMENT; ANESTHESIA
- Trial name
- MINS (NCT07098468)
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis, Pain Assessment
A Study to Evaluate the Effectiveness and Safety of Multiple Doses of Tapentadol(CG5503) in Patients Awaiting Joint Replacement Surgery
The purpose of this study is to evaluate in patients who are eligible for elective primary total or partial joint replacement of the hip or knee due to chronic osteoarthritis the efficacy (level of pain control) of CG5503 over 5…
- Conditions
- Osteoarthritis, Pain Assessment, Arthralgia
- Trial name
- NCT00361582
- Testing
- CG5503 IR; tapentadol
- Volunteers
- 669 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Opioid Use, Pain, Post Operative
A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery
Opioid addiction in post-operative patients is recognized but not fully understood; therefore, in order to address this growing crisis, it is essential to explore alternative approaches to managing pain and apply them to the…
- Trial name
- NCT05252858
- Testing
- nCAP Signal Relief Patch, Standard of Care
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Jacques E. Chelly
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Osteoarthritis, Arthroplasty
Heidelberg Registry for Hip and Knee Joint Implants and Revisions
The Endoprosthesis Registry Heidelberg (EPR-HD) is a clinical registry designed to systematically collect and analyze data from patients undergoing primary implantation or revision surgery of artificial hip and knee joints.
- Trial name
- EPR-HD (NCT06850818)
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- University Hospital Heidelberg
Osteoarthritis
Ergometer Cycling After Replacement of the Hip or Knee Joint
Despite the widespread use of hip and knee replacement surgery, there is a considerable lack of consensus regarding postoperative treatment and rehabilitation, mostly because of the lack of well-designed studies testing the…
- Trial name
- NCT00951990
- Testing
- Ergometer Cycling, No ergometer cycling
- Where
- 5 sites in Germany
- Volunteers
- 457 people
- Sponsor
- Verein zur Förderung der Rehabilitationsforschung in Schleswig-Holstein
Caregiver Burnout
Understanding Caregiver Burden for Hip and Knee Replacement Surgery Patients
Caregiver burden is the response to the emotional, financial, physical, psychological, and social stressors associated with having to care for another family member.
- Trial name
- NCT04838197
- Testing
- Questionnaires and Surveys
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Women's College Hospital