Clinical trials: Holmium Laser Enucleation of the Prostate
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Retrospective Review a Comprehensive Case Database of HoLEP Procedure Performed by a Single Surgeon
Persistent detrusor overactivity (DO) after transurethral prostatectomy results in symptomatic failure in more than one third of the patients.
- Trial name
- NCT01604148
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Benign Prostatic Hypertrophy, Holmium Laser Enucleation of the Prostate
Outpatient Holmium LASER Enucleation of the Prostate: Benefit of MOSES(TM) 2.0 Technology
The aim of this study is to compare the success rate of outpatient surgery after holmium LASER enucleation of the prostate (HoLEP) for the treatment of BPH with and without the use of the MOSES 2.0 effect.
- Trial name
- MOSES (NCT05768776)
- Testing
- HoLEP patients without MOSES(TM) 2.0 effect (open label), HoLEP patients with MOSES(TM) 2.0 effect (open label)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
Benign Prostatic Hyperplasia, Nocturia Associated With Nocturnal Polyuria
A Clinical Observation Study of a Chinese Patent Medicine Combined With Tamsulosin in Improving Sleep and Nocturia Symptoms After Enucleation of the Prostate
This study will test whether a traditional Chinese medicine called Lingze tablets, when added to the standard drug tamsulosin, can better improve sleep and nighttime urination problems in men after prostate surgery.
- Trial name
- NCT07357324
- Testing
- Tamsulosin Hydrochloride Sustained-Release Capsules, Lingze Tablets
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms
Emsella for Reducing tSUI After HOLEP
This study aims to investigate the effectiveness of the Emsella chair treatments at different timepoints. Before and after the holmium laser enucleation of the prostate (HoLEP).
- Conditions
- Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms, Enlarged Prostate (BPH)
- Trial name
- NCT07580404
- Testing
- Emsella chair
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
BPH With Urinary Obstruction, Male
HoLEP vs BPRP in the Management of a Large Volume (> 80 gm) Symptomatic BPH
To compare bipolar resection versus holmium laser enucleation for management of symptomatic large BPH (> 80 gm)
- Trial name
- NCT04935151
- Testing
- holmium laser enucleation of the prostate, Bipolar resection of the prostate
- Where
- 2 sites in Egypt
- Volunteers
- 112 people
- Sponsor
- Cairo University
Benign Prostatic Hyperplasia
IIT-2022-Simultaneous Urolift™ and Median Lobe Enucleation
To evaluate postoperative outcomes of BPH/Lower urinary tract symptoms, erectile function, and ejaculatory capacity of simultaneous UroLiftTM and Holmium laser enucleation of the prostatic median lobe.
- Trial name
- NCT06157164
- Testing
- UroLift™ System and Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Kansas Medical Center
Sexual Functions and Problems in the Adult
Evaluation of the Effects of Different Prostate Surgeries on Urinary and Sexual Function
The impact of of different surgical treatment modalities of benign prostatic hyperplasia in men on their sexual function is not well studied.
- Trial name
- NCT01810068
- Testing
- Holmium laser enucleation of the prostate, Monopolar transurethral resection of the prostate, Bipolar transurethral resection of the prostate
- Where
- Egypt
- Volunteers
- 262 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Feasibility and Utility of a Prehabilitation Program for Use in Patients With Benign Prostatic Hyperplasia Who Have Elected to Undergo Holmium Laser Enucleation of the Prostate (HoLEP).
Benign prostatic hyperplasia (BPH) is a debilitating condition which is highly prevalent in older males, up to 45% of those over the age of 45 are affected and 80% of those over the age of 70 are affected.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Outflow Obstruction
- Trial name
- NCT07552961
- Testing
- Comprehensive Prehabilitation Programming
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Holmium Laser Enucleation of the Prostate, Lung Protective Ventilation
Intraoperative Lung Mechanics Changes During HoLEP Surgery
This study aims to evaluate changes in driving pressure and static lung compliance during HoLEP surgery and to investigate their relationship with surgical and perioperative factors.
- Conditions
- Holmium Laser Enucleation of the Prostate, Lung Protective Ventilation, Driving Pressure
- Trial name
- NCT07607704
- Testing
- HoLEP surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Benign Prostatic Hyperplasia With Outflow Obstruction
Learning Curve of Tri-lobar HoLEP Versus En-bloc HoLEP
Several HoLEP techniques have been developed, with the conventional tri-lobar and the en-bloc approaches being the most commonly practiced.
- Trial name
- NCT07890103
- Testing
- Tri-lobar HoLEP, En-bloc HoLEP
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Benign Prostatic Hypertrophy With Outflow Obstruction, Overactive Detrusor
Prognostic Value of the Urinary Nerve Growth Factor in the Patients With Benign Prostatic Hyperplasia
Persistent detrusor overactivity (DO) after transurethral prostatectomy results in symptomatic failure in more than one third of the patients.
- Trial name
- NCT01781117
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Holmium laser enucleation system and morcellator
- Where
- South Korea
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- KYU-SUNG LEE
Enlarged Prostate (BPH), Enlarged Prostate With Lower Urinary Tract Symptoms
Ejaculatory-Sparing HoLEP vs Standard HoLEP
The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.
- Trial name
- NCT07631286
- Testing
- Ejaculatory-sparing (ES-sparing) HoLEP
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Benign Prostatic Hyperplasia (BPH)
Aquablation vs. Holmium Laser Enucleation of the Prostate in the Treatment of Benign Prostatic Hyperplasia in Medium to Large Size Prostates
Benign prostatic hyperplasia (BPH) is one of the most common diseases in men. As BPH progresses, surgical treatments often become necessary.
- Trial name
- ATHLETE (NCT04560907)
- Testing
- Aquablation, HoLEP
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Dr. med. Gautier Müllhaupt
Benign Prostatic Hyperplasia
HoLEP vs BipolEP in Management of BPH Patients With Large Prostates
This is a non-inferiority prospective randomized comparative clinical trial aiming to prove the non-inferiority of bipolar enucleation of the prostate in comparison to holmium laser enucleation of the prostate in management of…
- Trial name
- NCT06759194
- Testing
- Holmium Laser Enucleation of the Prostate, Bipolar Enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 98 people
- Sponsor
- Assiut University
Benign Prostatic Hyperplasia With Outflow Obstruction, Urinary Retention
Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate
The purpose of this study is to allow us to assess the effectiveness (or success) of starting pelvic floor physical therapy (i.e.
- Conditions
- Benign Prostatic Hyperplasia With Outflow Obstruction, Urinary Retention, Lower Urinary Tract Symptoms
- Trial name
- NCT06179654
- Testing
- Preoperative pelvic floor physical therapy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Cleveland Clinic
BPH (Benign Prostatic Hyperplasia)
HoLEP-ThuLEP - Comparing Lasers for BPH Surgery
Benign prostatic hyperplasia (BPH) is a very common condition in older men. As the prostate enlarges, it can press on the urethra and make urination difficult.
- Trial name
- HOT (NCT07565961)
- Testing
- Thulium Laser Enucleation of the Prostate (ThuLEP), Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
BPH (Benign Prostatic Hyperplasia), HoLEP
Comparison of Convective Water Vapor Ablation (Convective Water Vapor Energy, WAVE™) With the Rezum™ System Versus Holmium Laser Enucleation of the Prostate (HoLEP) Versus Bipolar Transurethral Resection of the Prostate (TUR-P) in Patients With Benign Prostatic Syndrome (BPS) - A Randomized Study
Benign prostatic enlargement (BPH/BPS) is one of the most common benign diseases in adult men. About 50% of men are affected by the age of 50, and between the ages of 70 and 80 the prevalence rises to 70-80%.
- Conditions
- BPH (Benign Prostatic Hyperplasia), HoLEP, Rezum, TURP(Transurethral Resection of Prostate)
- Trial name
- Vektor (NCT07204002)
- Testing
- Treatment BPH
- Volunteers
- 198 people
- Sponsor
- Medical University of Graz
HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia
Metabolic and Clinical Effects of Hyperchloremia During HoLEP Surgery.
This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change.
- Conditions
- HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia, Perioperative Management
- Trial name
- NCT07655830
- Testing
- HoLEP surgery
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Registry of MIUS for Benign Prostatic Obstruction
This national, multicenter, prospective registry aims to collect standardized perioperative and follow-up data on patients undergoing minimally invasive surgical management for benign prostatic obstruction (BPO) in Turkey.
- Trial name
- ReMIUS-BPO (NCT07159165)
- Testing
- Minimally invasive surgical treatment for benign prostatic obstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Ondokuz Mayıs University
Prostatic Hypertrophy
Impact of Intraoperative Instillation of Normothermal Saline on the Prevention of Intraoperative Hypothermia and Perioperative Morbidity of Prostatic Enucleation With Holmium Laser
For the treatment of benign prostatic hyperplasia (BPH), 2 types of endoscopic surgery are currently performed: transurethral prostate resection (TPR), the reference surgery, and laser prostatic enucleation (LPE).
- Trial name
- THERMHOLEP (NCT04761224)
- Testing
- Fluido® Irrigation Fluid Heater System
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph