Clinical trials: Holmium Laser Enucleation of the Prostate
Prostatic Hyperplasia
Impact of Bladder Underactivity on Treatment Outcomes of Laser Prostatectomy
The aim of this study was to evaluate an impact of preoperative bladder underactivity on treatment outcomes of photoselective vaporization of the prostate (PVP) or holmium laser enucleation of the prostate (HoLEP) in the…
- Trial name
- NCT02243540
- Where
- South Korea
- Volunteers
- 1,828 people
- Sponsor
- Seoul National University Hospital
Benign Prostatic Hyperplasia
Trial of HoLEP vs. PVP in Treating BPH in Patients With Bleeding Tendency
Patients presented for BPH surgery at our out patient clinic will be assessed for abnormal bleeding profile. Patients with bleeding tendency will be offered either HoLEP or Greenlight laser PVP based on prostate size cut off…
- Trial name
- NCT02293759
- Testing
- HoLEP, Greenlight laser PVP
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia With Outflow Obstruction, Urinary Retention
Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate
The purpose of this study is to allow us to assess the effectiveness (or success) of starting pelvic floor physical therapy (i.e.
- Conditions
- Benign Prostatic Hyperplasia With Outflow Obstruction, Urinary Retention, Lower Urinary Tract Symptoms
- Trial name
- NCT06179654
- Testing
- Preoperative pelvic floor physical therapy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Cleveland Clinic
BPH (Benign Prostatic Hyperplasia)
HoLEP-ThuLEP - Comparing Lasers for BPH Surgery
Benign prostatic hyperplasia (BPH) is a very common condition in older men. As the prostate enlarges, it can press on the urethra and make urination difficult.
- Trial name
- HOT (NCT07565961)
- Testing
- Thulium Laser Enucleation of the Prostate (ThuLEP), Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Learning Curve, Laser
The Learning Curve of Transurethral Holmium Laser Enucleation of the Prostate, Prospective Assessment
Despite the high-quality evidence supporting the safety and efficacy of Holmium laser enucleation of the prostate (HOLEP), wide adoption of the procedure is hindered by learning difficulties.
- Conditions
- Learning Curve, Laser, Prostate Hyperplasia
- Trial name
- NCT06038890
- Testing
- Holmium laser enucleation of the prostate using the veil-sparing technique
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom
A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate
This study compares the safety and efficacy of three endoscopic enucleation techniques for large prostates (>100 mL) in patients with benign prostatic hyperplasia (BPH): Thulium Fiber Laser Enucleation (ThuFLEP), Holmium Laser…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom, Bladder Outlet Obstruction
- Trial name
- NCT07627178
- Testing
- Thulium Fiber Laser Enucleation of the Prostate (ThuFLEP), Holmium Laser Enucleation of the Prostate (HoLEP), Bipolar Transurethral Enucleation of the Prostate (B-TUEP)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Sexual Functions and Problems in the Adult
Evaluation of the Effects of Different Prostate Surgeries on Urinary and Sexual Function
The impact of of different surgical treatment modalities of benign prostatic hyperplasia in men on their sexual function is not well studied.
- Trial name
- NCT01810068
- Testing
- Holmium laser enucleation of the prostate, Monopolar transurethral resection of the prostate, Bipolar transurethral resection of the prostate
- Where
- Egypt
- Volunteers
- 262 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia, Cognitive Functions
Comparative Neurocognitive Outcomes Following Prostate Surgery
This prospective observational cohort study aims to evaluate postoperative cognitive outcomes in patients undergoing surgical treatment for benign prostatic hyperplasia (BPH).
- Trial name
- NCT07468084
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Cengiz Canakci, MD
Benign Prostatic Hyperplasia
Thulium Fiber Laser (TFL) vs Holmium MOSES for Treatment of Benign Prostatic Hyperplasia (BPH)
Benign prostatic hyperplasia (BPH), the non-cancerous enlargement of the prostate, places pressure on the urethra and causes urination and bladder problems.
- Trial name
- NCT05240001
- Testing
- Thulium Fibre Laser, MOSES Holmium Laser
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Benign Prostate Hypertrophy(BPH)
Evaluation of the Application Effect of a Surgical Navigation System in HoLEP Surgery
3D imaging-assisted surgical navigation system was established using the following specific procedures: 1) Prostate MRI Acquisition and 3D Reconstruction: patient prostate MRI images are acquired, and professional engineers…
- Trial name
- NCT07251621
- Testing
- use the 3D imaging-assisted surgical navigation system during surgery
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese PLA General Hospital
BPH With Urinary Obstruction, BPH
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines.
- Conditions
- BPH With Urinary Obstruction, BPH, Hematuria, Same Day Discharge
- Trial name
- NCT05620784
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prostatic Hyperplasia, Stress Urinary Incontinence
Pelvic Floor Physical Therapy to Reduce Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate
Holmium laser enucleation of the prostate (HoLEP) is a surgical procedure used to treat benign prostatic hyperplasia (BPH). HoLEP involves the removal of obstructive prostatic tissue via an endoscopic approach to relieve…
- Trial name
- NCT06209307
- Testing
- Pelvic floor physical therapy
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Irvine
Benign Prostatic Hyperplasia (BPH)
Aquablation vs. Holmium Laser Enucleation of the Prostate in the Treatment of Benign Prostatic Hyperplasia in Medium to Large Size Prostates
Benign prostatic hyperplasia (BPH) is one of the most common diseases in men. As BPH progresses, surgical treatments often become necessary.
- Trial name
- ATHLETE (NCT04560907)
- Testing
- Aquablation, HoLEP
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Dr. med. Gautier Müllhaupt
Benign Prostatic Hyperplasia (BPH)
HoLEP in Management of BPH Patients With Predominant Voiding vs Storage LUTS: A Comparative Retrospective Study
Comparison in outcomes of a minimally invasive surgical modality (Holmium Laser Enucleation of Prostate) in management of voiding versus storage lower urinary tract symptoms associated with Benign Prostatic Hyperplasia
- Trial name
- NCT04178811
- Testing
- Holmium Laser Enucleation of Prostate
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Assiut University
Benign Prostatic Hyperplasia With Outflow Obstruction
Learning Curve of Tri-lobar HoLEP Versus En-bloc HoLEP
Several HoLEP techniques have been developed, with the conventional tri-lobar and the en-bloc approaches being the most commonly practiced.
- Trial name
- NCT07890103
- Testing
- Tri-lobar HoLEP, En-bloc HoLEP
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Urologic Diseases, Prostate Obstruction
Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures
The primary aim is to assess the impact of laser setting frequency and wattage during holmium laser enucleation of the prostate.
- Trial name
- NCT06531473
- Testing
- HoLEP
- Where
- United States
- Volunteers
- 278 people
- Sponsor
- Northwestern University
BPH (Benign Prostatic Hyperplasia), HoLEP
Comparison of Convective Water Vapor Ablation (Convective Water Vapor Energy, WAVE™) With the Rezum™ System Versus Holmium Laser Enucleation of the Prostate (HoLEP) Versus Bipolar Transurethral Resection of the Prostate (TUR-P) in Patients With Benign Prostatic Syndrome (BPS) - A Randomized Study
Benign prostatic enlargement (BPH/BPS) is one of the most common benign diseases in adult men. About 50% of men are affected by the age of 50, and between the ages of 70 and 80 the prevalence rises to 70-80%.
- Conditions
- BPH (Benign Prostatic Hyperplasia), HoLEP, Rezum, TURP(Transurethral Resection of Prostate)
- Trial name
- Vektor (NCT07204002)
- Testing
- Treatment BPH
- Volunteers
- 198 people
- Sponsor
- Medical University of Graz
Benign Prostate Obstruction (BPO)
The Effects of Holmium Laser Enucleation and Thulium Laser Enucleation on Continence, Urethral Stricture, and Sexual Function in Benign Prostatic Hyperplasia
This study aims to evaluate the effects of Holmium Laser Enucleation of the Prostate (HoLEP) and Thulium Laser Enucleation of the Prostate (ThuLEP), performed for the treatment of benign prostatic hyperplasia (BPH), on the…
- Trial name
- EHTCUS (NCT07334730)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- TC Erciyes University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Water Vapor Thermal Therapy Versus Ejaculation-Preserving HoLEP for Benign Prostatic Hyperplasia
This prospective comparative study will evaluate Water Vapor Thermal Therapy (Rezum) versus ejaculation-preserving Holmium Laser Enucleation of the Prostate (EP-HoLEP) in sexually active men with symptomatic benign prostatic…
- Trial name
- NCT07648875
- Testing
- Water Vapor Thermal Therapy, Ejaculation-Preserving Holmium Laser Enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Difficult Intubation, Holmium Laser Enucleation of the Prostate
Difficult Intubation in HoLEP Surgery
The goal of this observational study is to determine the incidence of difficult intubation and evaluate the associated clinical risk factors in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP) surgery under…
- Trial name
- NCT07688954
- Where
- Turkey (Türkiye)
- Volunteers
- 700 people
- Sponsor
- Ankara City Hospital Bilkent