Clinical trials: Home Mechanical Ventilation
Chronic Respiratory Failure
Family Connections
This study seeks to evaluate a Structured Family Deliberation that will serve as the primary intervention in a multicenter controlled trial involving families considering tracheostomy and home ventilation for the child.
- Trial name
- NCT05379439
- Testing
- Structured Family Deliberation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
Invasive Mechanical Ventilation, Children With Medical Complexity
Parent-to-parent Coaching While Awaiting Hospital Discharge With a Child With a Ventilator
The objective of the study is to pilot a parent-to-parent coaching model with experienced family members of children with Invasive Mechanical Ventilation (IMV) as parent coaches.
- Conditions
- Invasive Mechanical Ventilation, Children With Medical Complexity, Home Nursing, Empowerment
- Trial name
- NCT05880953
- Testing
- Parent-to-parent coaching
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Childhood Asthma, Allergy
AsthmaVent - Effect of Mechanical Ventilation on Asthma Control in Children
AsthmaVent is a multi-center study, investigating the association between indoor air quality and childhood asthma. In Denmark, we spend more and more time indoors.
- Trial name
- AsthmaVent (NCT02068573)
- Testing
- Ventilation
- Where
- 7 sites in Denmark
- Volunteers
- 46 people
- Sponsor
- University of Aarhus
Hospitalized Patient, Home Mechanical Ventilation
The PAINN Study - a Pilot Cross Sectional Study
Pain prevalence in hospitalized patients has been reported between 65% and 75%, indicating poor and/or insufficient management. In addition, pain prevalence has been estimated for separate groups of individuals with specific…
- Conditions
- Hospitalized Patient, Home Mechanical Ventilation, Pain, Pain Management
- Trial name
- PAINN (NCT06980987)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Respiratory Therapy, Respiration, Artificial
Initiation of Home Mechanical Ventilation at Home in Patients With Chronic Hypercapnic Respiratory Failure
Objective: To prove that initiation of chronic ventilatory support at home, in patients with chronic hypercapnic respiratory failure due to neuromuscular disease (NMD) or thoracic cage problem is not inferior compared to…
- Conditions
- Respiratory Therapy, Respiration, Artificial, Positive-Pressure Respiration, Neuromuscular Diseases
- Trial name
- Homerun (NCT03203577)
- Testing
- Initiation of mechanical ventilation
- Where
- Netherlands
- Volunteers
- 96 people
- Sponsor
- University Medical Center Groningen
Sleep-Disordered Breathing
Home Initiation of Noninvasive Positive Pressure Ventilation in Children With Medical Complexity
Children with medical complexity (CMC) often have trouble breathing at night and need to use a breathing machine. This breathing machine is called noninvasive positive pressure ventilation (NiPPV).
- Trial name
- NCT05881031
- Testing
- Home Initiation of NiPPV
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
Chronic Obstructive Pulmonary Disease
Home Mechanical Ventilation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Hypercapnic Response
The objective of this study is to evaluate the clinical benefits of home mechanical ventilation associated to oxygen therapy in COPD patients with chronic respiratory failure (CRF) who develop hypercapnia and nocturnal…
- Trial name
- NCT01120574
- Testing
- Home mechanical ventilation
- Where
- Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Long-term Ventilation at Home
Transition to LIVE (Long-term In Home Ventilation Engagement) Study
The rising prevalence of ventilator assisted individuals (VAIs) who depend on Home Mechanical Ventilation (HMV) is an escalating public health challenge with important social and economic implications.
- Trial name
- TTLive (NCT04180722)
- Testing
- aTouchAway™ platform
- Where
- 8 sites in Canada
- Volunteers
- 444 people
- Sponsor
- The Hospital for Sick Children
Hypercapnic Respiratory Failure, Sleep Disordered Breathing
Remote Monitoring to Improve Low Adherence in Non-invasive Ventilation
Patients are invited to participate in a trial to test a new way to optimise long-term use of non-invasive ventilation using remote monitoring.
- Conditions
- Hypercapnic Respiratory Failure, Sleep Disordered Breathing, COPD, Obesity Hypoventilation Syndrome (OHS)
- Trial name
- READ-NIV (NCT04884165)
- Testing
- Remote monitoring of home mechanical ventilation (NIV) using SRETT, Home mechanical ventilation (NIV) without remote monitoring
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Critical Illness, Mechanical Ventilation Complication
A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults
This study will apply an evidence based program to assist ICU survivors to overcome cognitive problems as a result of their critical illness.
- Conditions
- Critical Illness, Mechanical Ventilation Complication, Delirium, Cognitive Impairment
- Trial name
- PIC-UPS (NCT03972384)
- Testing
- Post-ICU Problem Solving
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Ohio State University
Chronic Respiratory Insufficiency
Non Invasive Mechanical Ventilation in Chronic Respiratory Insufficiency Patients During Rehabilitation
Patients with Chronic Obstructive Pulmonary Disease (COPD) and chronic respiratory insufficiency (CRI) have severe dyspnoea during exercise at low load.
- Trial name
- NCT01458314
- Testing
- Daily NIV during rehabilitation, Rehabilitation without NIV
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Fondazione Salvatore Maugeri
Amyotrophic Lateral Sclerosis, Home Mechanical Ventilation
Development in Home Mechanical Ventilation for Patient With Amyotrophic Lateral Sclerosis.
The aims of the study are to calculate the positive predictive value (PPV) of the codes for home mechanical noninvasive and invasive ventilation in patients with Amyotrophic lateral sclerosis in Denmark, and to describe the…
- Trial name
- NCT07819890
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ventilator Lung
Life-dependent Home Mechanical Ventilation
In Denmark, life-dependent home-mechanical ventilation (HMV) is given under the surveillance of a specifically trained respiratory patient caregiver (tPCG).
- Trial name
- NCT06151886
- Where
- Denmark
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pulmonary Disease, Chronic Respiratory Failure
Home Mechanical Ventilation Effectiveness and Air Leaks
Non invasive ventilation (NIV) usually presents air leaks that may determine the result of this treatment. The clinical usefulness of analyzing (and quantifying) these leaks during the adaptation period to NIV has not been…
- Conditions
- Pulmonary Disease, Chronic Respiratory Failure, COPD
- Trial name
- NCT01090986
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chronic Respiratory Failure
Telemedicine for Patients With Chronic Respiratory Insufficiency
In unstable patients needing oxygen and/or home mechanical ventilation, a nurse-centred TM programme (supported by continuous availability of a call centre and a pulsed oxygen system) is cost/effective saving health care…
- Trial name
- NCT00563745
- Testing
- telemedicine program
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Michele Vitacca
Asthma
Mechanical Heat Recovery Ventilation on House Dust Mite Sensitive Asthma
Asthma has become increasingly common in the UK, demanding our consideration of the cause. Many patients with asthma are allergic to house dust mites, which thrive in modern housing.
- Trial name
- NCT00148096
- Testing
- Mechanical Heat Recovery Ventilation
- Where
- United Kingdom
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Ventilator Weaning
Home-based Optimization of Mechanical Ventilation in Children
Some children who are born very early or have other congenital conditions may develop severe, long-term lung problems that make them need to use a breathing machine to live at home.
- Trial name
- HOMVent4Kids (NCT06055413)
- Testing
- Remote patient monitoring (RPM) bundle
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Home Mechanical Ventilation, Prolonged Mechanical Ventilation
Patient Characteristics, Feasibility, and Outcomes of a Home Mechanical Ventilation Program in a Developing Country
This study aims to describe the patient characteristics, feasibility, and outcomes of an home mechanical ventilation (HMV) program at a university hospital in Thailand.
- Trial name
- NCT02927613
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Thammasat University
Chronic Obstructive Pulmonary Disease, Neuromuscular Disease
Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation
The critical nature of respiratory diseases, the continuously increasing prevalence of these conditions, and the subjective perception of patients vis-à-vis their pulmonary function and health status underscore the importance of…
- Conditions
- Chronic Obstructive Pulmonary Disease, Neuromuscular Disease, Chest Wall Disorders, Obesity Hypoventilation Syndrome
- Trial name
- TeleMotiNIV (NCT01560741)
- Testing
- Telemonitoring tools, Usual Care
- Where
- Portugal
- Volunteers
- 128 people
- Sponsor
- Hospital Sao Joao
Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease
The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation
Patients suffering chronic hypercapnic respiratory insufficiency (e.g. in chronic obstructive pulmonary disease, obesity hypoventilation syndrome) benefit from home mechanical ventilation.
- Conditions
- Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease, Obesity Hypoventilation Syndrome, Restrictive Lung Disease
- Trial name
- NCT03506906
- Testing
- Sleep studies under noninvasive ventilation therapy, Routine tests
- Where
- Germany
- Volunteers
- 105 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V