Clinical trials: Homelessness
Homelessness, Youth
Transitioning Youth Out of Homelessness 2.5 (TYOH 2.5)
The idea for this study came from the research team's current study called Transitioning Youth Out of Homelessness (TYOH) 2.0, which provides coaching and a leadership guide to youth transitioning out of homelessness.
- Trial name
- NCT06425458
- Testing
- Co-Designed Strengths-Based Leadership Program
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV Prevention
Mobile Vehicle-Based Delivery of Lenacapavir Pre-Exposure Prophylaxis in Los Angeles County
This project evaluates the implementation strategy of the delivery of lenacapavir pre-exposure prophylaxis (LEN PrEP) - a newly available long-acting, injectable medication for human immunodeficiency virus (HIV) prevention - via…
- Trial name
- MOVE-LA (NCT07467018)
- Testing
- Community-based healthcare delivery, Lenacapavir
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Homelessness
A Pragmatic Trial Integrating Homelessness Diversion Services Into an Emergency Department Discharge System
The purpose of this study is to determine whether a homelessness diversion program integrated into a hospital emergency department (ED) will lower ED use, to identify characteristics of individuals most likely to benefit from…
- Trial name
- NCT05823220
- Testing
- Homeless diversion (HD), Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Use Disorder
Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness
Seventy to eighty percent of Veterans experiencing homelessness (VEH) smoke, which is four times the rate of the U.S. population and 2.5 times higher than among impoverished Americans.
- Trial name
- New HART (NCT07714200)
- Testing
- Cognitive Behavioral Therapy for Smoking Cessation, Nicotine Replacement Therapy, Bupropion
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Acute Care Service Utilization, Mental Health Status
Homeless Veterans and Peer Whole Health Coaching
Use of acute care services (e.g., hospitalizations, Emergency Department visits) contributes substantially to the cost of healthcare for Veterans. Homelessness is a robust social determinant of super utilization of acute care.
- Conditions
- Acute Care Service Utilization, Mental Health Status, Physical Health Status, Housing
- Trial name
- PWHC (NCT05176977)
- Testing
- Peer Support-Whole Health Coaching
- Where
- 3 sites in United States
- Volunteers
- 177 people
- Sponsor
- VA Office of Research and Development
Dietary Modification, Physical Activity
Evaluation of a Shelter-Based Diet and Physical Activity Intervention for Homeless Adults
The proposed study will utilize a randomized controlled trial design to pilot-test a 4-week shelter-based diet and physical activity intervention in a sample of homeless adults residing in the transitional shelter at The Bridge…
- Trial name
- NCT02427100
- Testing
- Diet/Physical Activity
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Youth, Homelessness
Generating Evidence for a Support Package to Stabilize Youth Trajectories Out of Homelessness
This project builds upon initial proof of concept work examining the optimal set of supports for youth who have recently exited homelessness - an intervention comprised of mental health and peer supports alongside transitional…
- Trial name
- NCT03277794
- Testing
- HOP-C, Transitional Case Management Only
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Centre for Addiction and Mental Health
Families Experiencing Homelessness and/or Housing Instability, Housing Stability
Silicon Valley Guaranteed Income Project
The goal of this clinical trial is to learn about how unconditional cash payments equivalent to $1,000 for 24 months (also called 'guaranteed income') might help families experiencing homelessness and/or unstable housing in Santa…
- Trial name
- SVGIP (NCT05698498)
- Testing
- Guaranteed Income, Public Benefits Information Session
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco
Hepatitis C Virus (HCV) Infection
Development of a Community-based HCV Treatment Completion Intervention Among HCV Positive Homeless Adults
This randomized controlled trial (RCT) will test the efficacy of a Community Health Worker/Registered Nurse (CHW-RN) HCV intervention for homeless individuals, many who are also drug users.
- Trial name
- NCT04513899
- Testing
- Community health worker (CHW)/ registered nurse (RN) [CHW/RN], Clinic-based Standard of Care (cbSOC) Program (control group)
- Where
- 7 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of California, Irvine
Tobacco Use Disorder, Homelessness
Abstinence Reinforcement Therapy (ART) for Homeless Veteran Smokers
The goal of this research study is to examine the effects of a treatment for helping homeless veterans who smoke to stop smoking. Participants in the study will be assigned to one of two study groups.
- Trial name
- NCT02245308
- Testing
- Nicotine Patches, mobile contingency management (mCM), Smoking cessation counseling
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- VA Office of Research and Development
Alcohol Use, Unspecified, Homelessness
Life Enhancing Alcohol-management Program
People experiencing chronic homelessness comprise a small yet high-morbidity, high-cost subset of the larger homeless population and are disproportionately impacted by alcohol-related harm.
- Conditions
- Alcohol Use, Unspecified, Homelessness, Harm Reduction, Community Based Participatory Research
- Trial name
- LEAP (NCT04302740)
- Testing
- LEAP
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Washington
COVID-19
Evaluation of Vaccination Coverage and Determinants of Success of the COVID-19 Vaccination Program Among Populations in Very Precarious Situations
The main objective of the study is to assess the level of vaccination coverage (VC) against COVID-19 among migrants, homeless and travelling community, according to their living conditions and housing.
- Trial name
- PREVAC (NCT05075941)
- Testing
- Vaccination coverage
- Where
- 2 sites in France
- Volunteers
- 3,811 people
- Sponsor
- Epicentre
Hospitalization, Patient Readmission
Intervening With and Improving Care for Patients at Risk for Frequent Hospital Admissions
Patients with frequent hospital admissions account for a disproportionate share of visits and costs. An intervention that can bridge the gap between hospital and community based care for a population of patients with frequent…
- Trial name
- NCT01292096
- Testing
- Provision of extra (care coordination and management) services
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Overdose, Harm Reduction
Shelter HArm Reduction Evaluation
The proposed study will use mixed methods research to examine overdose and other health-related impacts of harm reduction initiatives in NYC homeless shelters.
- Trial name
- SHARE (NCT07170072)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
Lung Diseases, Tuberculosis
Tuberculosis Prophylaxis in the Homeless--A Controlled Trial
To conduct a three-arm, randomized controlled trial of methods to improve adherence to biweekly directly observed prophylaxis (DOPT) for tuberculosis in homeless adults in San Francisco.
- Trial name
- NCT00005737
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Homelessness
Emergency Department Linkage to Care for Patients Experiencing Homelessness
In an effort to improve access to primary care at time of discharge, patients who are homeless will be given either enhanced follow up through a street medicine team or routine follow up in clinic.
- Trial name
- NCT07209072
- Testing
- Street medicine follow up
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Denver Health and Hospital Authority
Hepatitis C, Chronic
The No One Waits Study: Acceptability and Feasibility of Community-based Point-of-diagnosis HCV Treatment Study
Direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) offers a cure to those with chronic HCV infection. For marginalized communities, linkage to care services often aren't enough to overcome barriers to accessing the…
- Trial name
- NOW (NCT03987503)
- Testing
- Epclusa (SOF/VEL), Standard of care, Fibroscan® 430 Mini Plus
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Substance Use, Sexual Risk Behavior
Substance Use and Sexual Risk Reduction Intervention for Homeless Youth
The goal of this study is to evaluate a group-based motivational interviewing (MI)-delivered risk reduction program for homeless young adults.
- Trial name
- NCT02188797
- Testing
- Group MI risk reduction program
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RAND
Number of Emergency Department and Hospital Visits Among Adults Experiencing Homelessness, Medication Adherence
Interactive Care Coordination and Navigation:RCT To Assess the Impact of a mHealth Intervention for Homeless Individuals
People experiencing homelessness (PEH) are at exceptionally high risk of frequent emergency department (ED) and hospital use, poor functional outcomes, and increased morbidity and mortality from poorly managed chronic health…
- Conditions
- Number of Emergency Department and Hospital Visits Among Adults Experiencing Homelessness, Medication Adherence, Social Support, Pyschological Distress
- Trial name
- iCAN (NCT05365867)
- Testing
- iCAN Group
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Leticia R. Moczygemba
Substance Use Disorder, Mental Health Disorder
MISSION-CJ for Justice-Involved Homeless Veterans
The purpose of this study is to determine whether Maintaining Independence and Sobriety through Systems Integration, Outreach and Networking - Criminal Justice version (MISSION-CJ) is effective for reducing criminal recidivism…
- Conditions
- Substance Use Disorder, Mental Health Disorder, Homelessness
- Trial name
- MISSION-CJ (NCT04523337)
- Testing
- Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking- Criminal Justice, Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking Peer Support
- Where
- 3 sites in United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development