Clinical trials: Homelessness
Smoking
A Pilot Randomized Controlled Trial of Financial Incentives, Text Messaging, and Usual Care for Homeless Smokers
The QUIT (Quitting with Usual Care, Incentives, and Technology) Smoking Study is a 3-arm pilot randomized controlled trial that will test the effect of 2 different experimental smoking cessation interventions relative to a…
- Trial name
- QUIT (NCT02565381)
- Testing
- Transdermal nicotine patch, In-person smoking cessation counseling, Contingent financial rewards for smoking abstinence
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Massachusetts General Hospital
Substance-related Disorders
Voucher-Based Incentives in a Prevention Setting
This study evaluates a contingency management program that rewards homeless, non-treatment-seeking substance abusing men who have sex with men (MSM) for abstaining from drugs and for performing prosocial behaviors.
- Trial name
- VIPS (NCT00607269)
- Testing
- Voucher-Based Reinforcement Therapy
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Friends Research Institute, Inc.
Hepatitis C Virus (HCV) Infection
Development of a Community-based HCV Treatment Completion Intervention Among HCV Positive Homeless Adults
This randomized controlled trial (RCT) will test the efficacy of a Community Health Worker/Registered Nurse (CHW-RN) HCV intervention for homeless individuals, many who are also drug users.
- Trial name
- NCT04513899
- Testing
- Community health worker (CHW)/ registered nurse (RN) [CHW/RN], Clinic-based Standard of Care (cbSOC) Program (control group)
- Where
- 7 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of California, Irvine
Substance Abuse
Evaluation of Treatments for Homeless Youths
Youth who leave home for the streets are at significantly more risk for a multitude of problems, yet little research is available to guide treatment intervention efforts with this population.
- Trial name
- NCT01143792
- Testing
- Community Reinforcement Approach (CRA) + HIV prevention, Case Management + HIV Prevention, Motivational Enhancement Therapy (MET) + HIV prevention
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Ohio State University
Veterans, Homeless Persons
Improving Housing Outcomes for Homeless Veterans
Many homeless Veterans with serious mental illness (SMI) enroll in the VA's Supported Housing (VASH) program but struggle to obtain and sustain housing.
- Conditions
- Veterans, Homeless Persons, Mentally Ill Persons
- Trial name
- NCT03646149
- Testing
- Housing Skills Training Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Office of Research and Development
Psychotic Disorders, Schizophrenia
A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness
This is a prospective study using a concierge model of customized adherence enhancement and long-acting injectable antipsychotic (CAL-Concierge) in 30 individuals with schizophrenia or schizoaffective disorder at risk for…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Medication Adherence
- Trial name
- CAL-C (NCT02085447)
- Testing
- CAE-L
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
Homeless Persons
Effect of a Rent Subsidy and Mentoring on Youth Transitioning Out of Homelessness
Compared to the vast amount of literature about the risk factors associated with young people entering and becoming entrenched in homelessness, much less is known about how to facilitate and sustain transitions off the streets.
- Trial name
- NCT03779204
- Testing
- Mentorship, Rent Subsidies
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Latent Tuberculosis Infection
Nurse-Led Community Health Worker Adherence Model in 3HP Delivery Among Homeless Adults at Risk for TB Infection and HIV
Tuberculosis (TB) is the prototypical disease of poverty as it disproportionately affects marginalized and impoverished communities.
- Trial name
- 3HP-LTBI (NCT03702049)
- Testing
- Nurse-led Community Health Worker TBI (RN/CHW TBI) program
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of California, Irvine
Tobacco Smoking
Financial Incentives for Homeless Smokers: A Community-based RCT
This community-based randomized controlled trial will test the effect of contingent financial rewards on smoking abstinence among homeless-experienced adult cigarette smokers.
- Trial name
- NCT04445662
- Testing
- Financial incentives, Varenicline, Tobacco coaching
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Massachusetts General Hospital
Youth, Homelessness
The Identity Project
Understanding how to create successful pathways out of homelessness is crucial. Thirty young people (aged 18 - 26 years) who have transitioned out of homelessness within the past three years will be offered scholarships to…
- Trial name
- TIP (NCT03772522)
- Testing
- dk Leadership
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Feasibility
The EMERGE Project: Feasibility of Assessing Economic and Sexual Risk Behaviors Using Text Messages in Young Adults
As part of the development of the Engaging Microenterprise for Resource Generation and Health Empowerment (EMERGE) Project, the study team will conduct a single-group study to examine the feasibility of assessing economic and…
- Trial name
- NCT03237871
- Testing
- Text-message survey and informational text messages
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Alcohol Dependence
Pilot Study of Depot NTX in Homeless Veterans
Almost 200,000 veterans are homeless each night, about one-quarter to one-third of homeless adults in the U.S. Half need treatment for a substance use disorder, usually alcohol dependence, but sobriety is often required to access…
- Trial name
- NCT01155869
- Testing
- Depot naltrexone, Oral Naltrexone
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- US Department of Veterans Affairs
Housing Problems, Drug Use
ED-Home Pilot Study
This is a single-arm pilot study to test the feasibility of homelessness prevention and substance use interventions to be delivered to at-risk patients in the Bellevue Hospital emergency department (ED).
- Conditions
- Housing Problems, Drug Use, Alcohol; Use, Problem
- Trial name
- NCT03864341
- Testing
- Referral to homelessness prevention services, Substance use services, Follow-up
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Youth, Homelessness
Generating Evidence for a Support Package to Stabilize Youth Trajectories Out of Homelessness
This project builds upon initial proof of concept work examining the optimal set of supports for youth who have recently exited homelessness - an intervention comprised of mental health and peer supports alongside transitional…
- Trial name
- NCT03277794
- Testing
- HOP-C, Transitional Case Management Only
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Centre for Addiction and Mental Health
Homelessness, Youth
Transitioning Youth Out of Homelessness 2.5 (TYOH 2.5)
The idea for this study came from the research team's current study called Transitioning Youth Out of Homelessness (TYOH) 2.0, which provides coaching and a leadership guide to youth transitioning out of homelessness.
- Trial name
- NCT06425458
- Testing
- Co-Designed Strengths-Based Leadership Program
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Depression, Anxiety
The Efficacy of Cranial Electrostimulating Therapy for Depression and Anxiety Among Homeless Adults
This is a trial of the use of cranial electrostimulating therapy for depression and anxiety among homeless adults.
- Trial name
- NCT02732561
- Testing
- Alpha Stim device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Lung Cancer, Tobacco Use
Lung Cancer Screening Navigation for Homeless People
The investigators will conduct a pragmatic clinical trial to test the effect of patient navigation on lung cancer screening (LCS) low-dose computed tomography (LDCT) completion among Boston Health Care for the Homeless Program…
- Conditions
- Lung Cancer, Tobacco Use, Homelessness
- Trial name
- NCT04308226
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Dietary Modification, Physical Activity
Evaluation of a Shelter-Based Diet and Physical Activity Intervention for Homeless Adults
The proposed study will utilize a randomized controlled trial design to pilot-test a 4-week shelter-based diet and physical activity intervention in a sample of homeless adults residing in the transitional shelter at The Bridge…
- Trial name
- NCT02427100
- Testing
- Diet/Physical Activity
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes Mellitus, Type 2, Housing Problems
Diabetes Homeless Medication Support
This randomized pilot trial of the Diabetes Homeless Medication Support intervention vs. brief diabetes education will test the perception and feasibility of anticipated study procedures and refine randomization and blinding.
- Conditions
- Diabetes Mellitus, Type 2, Housing Problems, Psychological Distress
- Trial name
- D-HOMES (NCT05258630)
- Testing
- Diabetes Homeless Medication Support (D-Homes), Enhanced usual care
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hennepin Healthcare Research Institute
HIV/AIDS, Housing Problems
Enhanced Housing Placement Assistance
Randomized controlled trial of housing placement assistance for homeless persons with HIV
- Trial name
- EHPA (NCT03334825)
- Testing
- Enhanced housing placement assistance, Standard housing placement assistance
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- New York City Department of Health and Mental Hygiene