Clinical trials: Homosexuality
HIV Prevention Program
Testing of the JomPrEP App for HIV Prevention Among Malaysian MSM
This project will involve conducting a Type I Hybrid Implementation Science trial to assess the efficacy of the JomPrEP app while measuring contextual implementation factors to guide its future adoption and scale-up.
- Trial name
- JomPrEP (NCT05325476)
- Testing
- JomPrEP App, Inactivated JomPrEP app
- Where
- 2 sites in Malaysia
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
HIV Transmission, Transtheoretical Model of Change
Partner Services Pre-exposure Prophylaxis (PS-PrEP)
This study evaluates the feasibility (reach, adoption, safety and implementation) and initial efficacy (higher linkage to care) of the Partner Services Pre-exposure Prophylaxis (PS-PrEP) intervention versus phone based…
- Trial name
- PS-PrEP (NCT02749955)
- Testing
- PS-PrEP Intervention Group, PrEPLine Control Group
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Suicide
Implementing Evidence Informed Practices in Schools to Address LGBTQ Adolescent Suicide
Reducing youth suicide in the U.S. is a national public health priority. Sexual and gender minority adolescents are at elevated risk for suicide. Safer school environments, however, can decrease this risk.
- Trial name
- RLAS (NCT02875535)
- Testing
- RLAS
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
HIV, PrEP
Behavioral Intervention for PrEP Service Utilization Among Chinese MSM: A HAPA and CEI Integrated Model
The goal of this clinical trial is to evaluate the effectiveness of a novel, intelligent intervention platform in bridging the "intention-behavior gap" for pre-exposure prophylaxis (PrEP) uptake among men who have sex with men…
- Conditions
- HIV, PrEP, MSM, Behavior Changes
- Trial name
- NCT06931106
- Testing
- HAPA and CEI behavioral intervention, HAPA-based intervention
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Peking University
Human Immunodeficiency Virus, Stigma, Social
Mitigating Sexual Stigma Within Healthcare Interactions Improve Engagement of MSM in HIV Prevention
The purpose of this study is to explore drivers and mitigators of anal sex stigma in healthcare, and then to develop and pilot an intervention for health workers that mitigates the deterrent effects of this stigma on the…
- Conditions
- Human Immunodeficiency Virus, Stigma, Social, Patient Engagement
- Trial name
- NCT04779736
- Testing
- A set of implementation strategies to reduce sexual stigma
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis
STI Prophylaxis and Emergence of Antimicrobial Resistance
The goal of this observational study is to understand the risk of antibiotic resistance and changes in the human microbiome (bacteria that live inside and on us), if people use antibiotics to prevent sexually transmitted…
- Conditions
- Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis, Antibiotic Resistance, Bacterial, Microbiome
- Trial name
- SPEAR (NCT06778083)
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University College, London
Sexually Transmitted Infection (STI), Mycoplasma Genitalium Infection
Community Burden of MG Infection
Objective: To assess the burden and the transmission dynamics of Mycoplasma genitalium (MG) infection in men who have sex with men in Hong Kong.
- Trial name
- NCT06793605
- Where
- Hong Kong
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
STI
Population Burden of STI and Implication for Intervention in Hong Kong
This is a 5-year cross-disciplinary sexually transmitted infection (STI) project involving a) territory-wide and community-based studies (survey and specimen collection); b) simulation of STI transmission dynamics and comparison…
- Trial name
- NCT04793841
- Testing
- self-sampling kits for STI testing in laboratory
- Where
- Hong Kong
- Volunteers
- 1,977 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV/AIDS
Biomedical HIV/AIDS Prevention Program Yunnan
B-HAPPY is an implementation project to study the process by which pre-exposure prophylaxis (PrEP) is introduced and integrated into a specific international health system facing high rates of HIV incidence among men who have sex…
- Trial name
- B-HAPPY (NCT03992274)
- Testing
- Enhanced implementation of PrEP
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Columbia University
Recreational Drug Use
Chemsex Engagement and HIV Biomedical Prevention in MSM
HIV biomedical prevention through treatment-as-prevention (TasP) and pre-exposure prophylaxis (PrEP) is highly efficacious for reducing HIV transmission risk.
- Trial name
- NCT05031832
- Testing
- HIV test
- Where
- Hong Kong
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pre-Exposure Prophylaxis (PrEP), Counseling
Filling Gaps in the HIV Pre-exposure Prophylaxis Cascade Through Counseling
This study s objective is to test the acceptability and feasibility of a guide to facilitate counseling about HIV prevention, focusing on HIV pre-exposure prophylaxis (PrEP).
- Conditions
- Pre-Exposure Prophylaxis (PrEP), Counseling, Sexual and Gender Minorities
- Trial name
- NCT06710171
- Testing
- Counseling, List of resources
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV/AIDS
Using Open Contest and Neuro-influence Experiment to Develop and Evaluate PrEP Promotion Messages for High Risk Men
The aim of this study is to examine the utility of neuroimaging technique to evaluate pre-exposure prophylaxis (PrEP) promotion messages for men who have sex with men (MSM) at risk of HIV in Baltimore.
- Trial name
- NCT04166851
- Testing
- PrEP campaign messages developed via open contest, PrEP campaign messages developed via social marketing approach
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV Infections
Young Men's Health Project Targeting HIV Risk Reduction and Substance Abuse
YMHP is a counseling intervention program for which the goals are to better understand HIV-prevention focused self-management behaviors among HIV-negative YMSM, and to study the implementation of YMHP to improve portability and…
- Trial name
- YMHP (NCT03577301)
- Testing
- Clinic-based Delivery, Remote Delivery, Multi-modal Delivery
- Where
- 3 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Florida State University
Gonorrhea, Chlamydia
Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Men
The purpose of this study is to understand if taking an antibiotic called doxycycline by mouth as soon as possible after sexual contact without a condom can reduce the risk of sexually transmitted infections (STIs), including…
- Conditions
- Gonorrhea, Chlamydia, Syphilis
- Trial name
- NCT03980223
- Testing
- Doxycycline Hyclate Delayed-Release 200 mg
- Where
- 3 sites in United States
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV, Sexually Transmitted Infections
Connect 'n Unite: Couples-Based HIV/STI Prevention for Drug-Involved, Black MSM
The study has the following primary aims: (1) to test whether participants assigned to CNU (a 7-session, manualized intervention entitled "Connect 'n Unite") engage in lower HIV/STI behavioral risk compared to participants…
- Trial name
- CNU (NCT01394900)
- Testing
- CNU Intervention, WP Intervention
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Infections
HealthMindr App to Increase Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex With Men (MSM)
This study is a randomized controlled clinical trial of a theoretically based mobile app, HealthMindr, to increase pre-exposure prophylaxis (PrEP) uptake among men who have sex with men (MSM) to prevent human immunodeficiency…
- Trial name
- NCT03763942
- Testing
- HealthMindr App, Control App
- Where
- 3 sites in United States
- Volunteers
- 658 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV
Advanced HIV Prevention (PrEP Chicago)
This study will evaluate the feasibility of a network intervention to train individuals to disseminate PrEP information and motivate initial PrEP interest and knowledge of PrEP in their social networks.
- Trial name
- NCT02896699
- Testing
- PrEP Intervention Group, Control Group
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Hiv
ANRS 12415 - Quali PrEP Cambodia
Hypothesis: Hypothesis 1 : Regarding the recentness of preexposure prophylaxis (PrEP) implementation with an uptake of 20% and according to the first consultative meeting, awareness and acceptability of PrEP seems to be low in…
- Trial name
- ANRS 12415 (NCT05091489)
- Testing
- Qualitative assessment about PrEP acceptability
- Where
- Cambodia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Social Network Strategy, HIV Self Testing
SNS to Increase HIV Testing Uptake and Linkage to Double Cascade Services Among Adolescent MSM and TGW in Thailand
UNAIDS aims to end AIDS by 2030 using "90-90-90" diagnosis-treatment-viral suppression targets. Thailand has achieved elimination of HIV mother-to-child transmission, but continues to see new infections among adolescent men who…
- Conditions
- Social Network Strategy, HIV Self Testing, Men Who Have Sex With Men
- Trial name
- NCT04953858
- Testing
- Social network strategy (SNS)
- Where
- Thailand
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University