Clinical trials: Hopefulness
Head and Neck Cancer
Head and Neck Cancer Omics/Integrated Precision Medicine (HOPE)
Study Background and Rationale Head and neck cancer (HNC) is the sixth leading cause of cancer-related death, with over 650,000 new cases diagnosed worldwide each year.
- Trial name
- HOPE (NCT07190573)
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
Mental Illness, Social Isolation
"Recovery 4 US" - A Photovoice-based Social Media Program
This study is a randomized trial evaluating "Recovery 4 US", a social media program aimed at the enhancement of community participation and overall recovery of individuals with psychiatric disabilities.This innovative e-mental…
- Conditions
- Mental Illness, Social Isolation, Loneliness
- Trial name
- R4US (NCT03266614)
- Testing
- Recovery 4 Us
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Boston University Charles River Campus
Hepatitis B， Chronic, Hepatitis C
The HOPE Study: Characterizing Patients With Hepatitis B and C
This is an observational, longitudinal, prospective study for sample collection and evaluation for future therapy or disease progression of chronic hepatitis B and C.
- Trial name
- NCT02995252
- Testing
- Blood draws, Tenofovir Alafenamide, Knowledge Index Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Stroke, Advance Care Planning
The Impact of an Advance Care Planning Game on Life-Sustaining Treatment Preferences, Depression, and Hope in Older Adults With Stroke
Stroke is the world's third leading cause of death and a major source of disability, with high rates of recurrence and mortality that often limit patients' ability to express their values and treatment preferences.
- Trial name
- NCT07235839
- Testing
- ACP Block Game Intervention
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- Lotung Poh-Ai Hospital
Anaplastic Thyroid Cancer
Phase II Study Assessing the Efficacy and Safety of Lenvatinib for Anaplastic Thyroid Cancer
The purpose of this phase Ⅱ study is to assess the efficacy and safety of lenvatinib for anaplastic thyroid cancer patients who are diagnosed as unresectable. The total duration of the study will be 30 months.
- Trial name
- HOPE (NCT02726503)
- Testing
- Lenvatinib
- Where
- 23 sites in Japan
- Volunteers
- 39 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Anxiety
A Mind-Body Medicine Curriculum for Peer Counselors
This study will evaluate a Mind-Body Medicine curriculum for high school peer counselors in order to answer the following research questions: 1.
- Trial name
- NCT03718845
- Testing
- Mind-Body Medicine Curriculum
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine
Advanced Malignant Mesothelioma, Carcinoma of the Appendix
Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
RATIONALE: An orientation and patient education program and telephone counseling may help improve the quality of life in patients with peritoneal surface malignancies.
- Conditions
- Advanced Malignant Mesothelioma, Carcinoma of the Appendix, Ovarian Sarcoma, Ovarian Stromal Cancer
- Trial name
- HOPE (NCT01126346)
- Testing
- HIPEC Orientation, Consultation with Survivorship Navigator, Questionnaires
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Dementia
Pilot Study of the Living With Hope Program for Family Caregivers of Persons With Dementia Residing in Long Term Care
Hope is important for family/friends of persons with dementia residing in Long Term Care Facilities. Our research team has developed a program (Living with Hope) to increase hope and quality of life of family caregivers.
- Trial name
- NCT02038192
- Testing
- Living with Hope Program, Stories of the Present
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Alberta
Depression
Programa Esperanza (Project Hope): A Depression Program for Older Latinos With Chronic Medical Conditions
The purpose of this study is to determine whether individually-administered Problem Solving Treatment is effective in managing depressive symptomatology in 250 primarily Spanish-speaking Latino patients ≥55 years of age or older…
- Trial name
- NCT02459860
- Testing
- Problem Solving Treatment, Enhanced Usual Care
- Volunteers
- 259 people
- Sponsor
- University of Southern California
Breast Carcinoma, Colorectal Carcinoma
HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics
This clinical trial studies the effectiveness of a web-based cancer education tool called Helping Oncology Patients Explore Genomics (HOPE-Genomics) in improving patient knowledge of personal genomic testing results and cancer…
- Conditions
- Breast Carcinoma, Colorectal Carcinoma, Lung Carcinoma, Malignant Solid Neoplasm
- Trial name
- NCT04905082
- Testing
- Best Practice, Educational Intervention, Genomic Profile
- Where
- United States
- Volunteers
- 465 people
- Sponsor
- City of Hope Medical Center
Drugs of Abuse
An Evaluation of California's Experiment With HOPE
The phase I evaluation is intended to assess whether or not frequent drug testing and immediate short-term incarceration for drug use and/or other violations and mandated drug treatment for multiple violations, reduces the…
- Trial name
- NCT01237691
- Testing
- HOPE supervision, Parole-as-usual
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Pepperdine University
Idiopathic Pulmonary Fibrosis
High Oxygen Delivery to Preserve Exercise Capacity in Idiopathic Pulmonary Fibrosis Patients Treated With Nintedanib
The purpose is to determine if patients with idiopathic pulmonary fibrosis (IPF) taking nintedanib will have improved exercise endurance, breathlessness and quality of life if breathing 60% oxygen compared to standard of care…
- Trial name
- HOPE-IPF (NCT02551068)
- Testing
- 60% Oxygen, Standard of Care
- Where
- 8 sites in Canada
- Volunteers
- 78 people
- Sponsor
- University of British Columbia
Recurrent Ovarian Carcinoma
Helping Ovarian Cancer Patients Cope With Their Illness (HOPE)
This clinical trial compares the effect of the Helping Ovarian Cancer Patients Cope with Their Disease (HOPE) intervention to usual care for the reduction of hopelessness and helplessness in patients with ovarian cancer that has…
- Trial name
- NCT06666218
- Testing
- Behavioral Intervention, Electronic Health Record Review, Interview
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Fred Hutchinson Cancer Center
Fabry Disease
Study Based on Electronic Health RecOrds to Identify Patients at High-risk of Fabry DiseasE (HOPE Fabry)
Primary objective: To estimate the prevalence of patients who are at high-risk for Fabry Disease (FD) in the Cleveland Clinic, Abu Dhabi (CCAD) United Arab Emirates (EMR) database from May 2016 to May 2022, according to the…
- Trial name
- NCT05671770
- Where
- United Arab Emirates
- Volunteers
- 15 people
- Sponsor
- Sanofi
Heart Transplant Failure and Rejection, Coronary Artery Disease
Percutaneous Coronary Intervention in Patients witH OrthotoPic hEart Transplantation: the PCI-HOPE a Multicenter Study.
This is a retrospective, multicenter, study including patients undergone to one or more percutaneous revascularization after OHT.
- Trial name
- PCI-HOPE (NCT03538509)
- Testing
- PCI and implantation drug eluting stent or bare metal stent
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fabrizio D'Ascenzo
Mental Health Literacy, Depression Literacy
Online HOPE Intervention on Mental Health Literacy Among Youths in Singapore: An RCT Protocol
The author developed the HOPE intervention based on a systematic review (Tay, Tay, \& Klainin-Yobas, 2018). The overall aim of the study is to test the effectiveness of the online HOPE intervention in enhancing mental health…
- Conditions
- Mental Health Literacy, Depression Literacy, Psychological Well-being, Stress, Psychological
- Trial name
- NCT04266119
- Testing
- Online HOPE intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Laughter Yoga
The Effect of Laughter Yoga on Hope and Well-Being Levels of Earthquake Victim Mothers
In Turkey, on February 6, 2023, an earthquake measuring 7.7 in magnitude centered in the Pazarcık district of Kahramanmaraş Province, followed by a second earthquake measuring 7.6 in magnitude centered in Elbistan, caused the…
- Trial name
- NCT06757036
- Testing
- Laughter Yoga
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Firat University
Eco-anxiety, Psychological Distress
The Impact of an Art and Philosophy-based Intervention on Children's Eco-anxiety
Objective: To examine the impact of climate change on children's mental health by comparing the effectiveness of an arts only intervention (ABI) and an arts and philosophy-based intervention (APBI) on children's eco-anxiety…
- Conditions
- Eco-anxiety, Psychological Distress, Tolerance to Distress, Hope
- Trial name
- NCT06937021
- Testing
- Art and philosophy intervention (APBI), Art based intervention (ABI)
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Bishop's University
Pneumonia, Viral, Covid-19
Chloroquine Phosphate Against Infection by the Novel Coronavirus SARS-CoV-2 (COVID-19): The HOPE Open-Label, Non Randomized Clinical Trial
This is an open label clinical study to evaluate the activity of chloroquine phosphate in patients with SARS-CoV-2 virus infection.
- Trial name
- HOPE (NCT04344951)
- Testing
- UNIKINON (Chloroquine phosphate) 200mg tablets
- Where
- 8 sites in Greece
- Volunteers
- 29 people
- Sponsor
- Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
Malnutrition, Child
Hens Hatching Hope
The study is a prospective community-cluster non-randomized trial that will evaluate the effectiveness of a program that will provide 30-day egg vouchers to mothers of 6 to 24 month-old children living in rural areas of Intibucá…
- Trial name
- NCT04721197
- Testing
- Egg vouchers, Standard of Care
- Where
- Honduras
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University