Clinical trials: Hormonal Changes
Appetite Regulation
Brain Activity and Hormonal Changes During Food Administration
The amount and kind of food which is ingested influences the regulation of meal size. Neural signals from the gastrointestinal tract travel via the vagus nerve to the brainstem and thalamus, which projects to the rest of the…
- Trial name
- NCT01644539
- Testing
- Water with guar gum - Non Caloric, Chocolate milk - Oral Caloric, Chocolate milk - Intra Gastric Caloric
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Nocturia, Menopause
Hormonal Influences on Diuresis
The aim of this study was to observe the effect of hormonal treatment (oral or transdermal substitution therapy) on diuresis (salt and water diuresis) and lower urinary tract symptoms (LUTS) in postmenopausal women
- Conditions
- Nocturia, Menopause, LUTS, Diuresis
- Trial name
- HODI (NCT04891926)
- Testing
- ICIQ FLUTS Questionaires, Frequency Volume Chart, Renal Function Profile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Major Depressive Disorder, Sexual Behavior
The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling
Large register based work has shown that starting on oral contraceptives (OCs) is associated with an increased risk of developing depressive episodes.
- Conditions
- Major Depressive Disorder, Sexual Behavior, Mood Disturbance, Mood Change
- Trial name
- NCT05212389
- Testing
- Femicept
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Infantile Spasms
Trial of the Modified Atkins Diet in Infantile Spasms Refractory to Hormonal Therapy
Infantile spasms comprise an infantile epileptic encephalopathy characterized by hypsarrhythmia on EEG, and frequent neurodevelopmental regression. Unfortunately the treatment of this disorder remains difficult.
- Trial name
- NCT01549288
- Testing
- modified Atkins diet, no dietetic input
- Where
- India
- Sponsor
- Lady Hardinge Medical College
Polycystic Ovary Syndrome
Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome
To assess the effects on hormonal and metabolic changes in the PCOs patients after ingestion of Arabic gum
- Trial name
- GA&PCO (NCT04215380)
- Testing
- Acacia Senegal extract, Pectin
- Where
- Sudan
- Volunteers
- 60 people
- Sponsor
- Lamis Kaddam
Vasomotor Symptoms Associated With Menopause, Hot Flashes
A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 52 Weeks in Women Who Have Been Through the Menopause
Researchers are looking for a better way to treat women who have hot flashes after they have been through the menopause. Hot flashes are caused by the hormonal changes that happen when a woman's body has been through the…
- Trial name
- OASIS-3 (NCT05030584)
- Testing
- Elinzanetant (BAY3427080)
- Where
- 86 sites in United States, Belgium and 7 more
- Volunteers
- 628 people
- Sponsor
- Bayer
Breast Cancer, Endometrial Cancer
Endometrial Changes in Breast Cancer Women With or Without Hormonal Therapies
A history of breast cancer is a risk factor for the development of endometrial pathologies, such as typical and atypical glandular hyperplasia, endometrial polyps, uterine fibroids, endometrial adenocarcinoma and uterine sarcoma…
- Trial name
- BETA-1 (NCT03898947)
- Testing
- Diagnostic hysteroscopy and targeted endometrial biopsy
- Volunteers
- 1,329 people
- Sponsor
- Università degli Studi dell'Insubria
Appetite Regulation, Healthy Young Adults
Satiety Evaluation of Mature Okra Flour-incorporated Biscuit
This study aims to evaluate whether eating biscuits made with mature okra flour can help young adults feel fuller (enhance satiety) and change certain blood markers compared to eating standard biscuits.
- Trial name
- MOFB (NCT07631663)
- Testing
- Mature Okra Flour-incorporated Biscuit (MOFB), Control Biscuit
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Advanced Nonsmall Cell Lung Cancer
Hormone Changes in Women With Stage IIIB or Stage IV Non-Small Cell Lung Cancer Receiving Erlotinib
Studying samples of blood in the laboratory from patients receiving erlotinib may help doctors learn more about the effects of erlotinib on hormone levels.
- Trial name
- NCT00602433
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northwestern University
Glucose Metabolism, Hormonal Changes
Long Time Metabolic Changes Induced by Genetically Modified Potatoes
In this study the effects of genetically modified potatoes on the human metabolism will be observed. Healthy volunteers receive for one week muffins, produced with starch from a genetically modified potato or with a normal…
- Conditions
- Glucose Metabolism, Hormonal Changes, Satiety
- Trial name
- NCT00953602
- Testing
- Genetically modified potato
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Diabetes Mellitus, Type 2, Gestational Diabetes
Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders.
The first aim of this study is to describe maternal hormonal and inflammatory changes during pregnancy in women that differ metabolically (limited to women with type 2 diabetes, gestational diabetes and/or overweight).
- Conditions
- Diabetes Mellitus, Type 2, Gestational Diabetes, Overweight and Obesity, Pregnancy in Diabetic
- Trial name
- HI-MET (NCT04617405)
- Testing
- No interventions
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
Epileptic Spasms, Failed Hormonal Therapy
Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study
This study has been planned to compare the efficacy and tolerability of topiramate, a commonly used second line agent, with modified Atkins diet in children with epileptic spasms refractory to hormonal treatment, in a randomized…
- Trial name
- TOPAMAD (NCT05958160)
- Testing
- Modified Atkins diet, Topiramate
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Lady Hardinge Medical College
Menopause Surgical
Hormonal Regulation of Cardiometabolic Health Study
The goal of this observational study is to understand how the loss of ovarian function after oophorectomy affects the health and well being of women aged 35-50. The study focuses on four areas: 1.
- Trial name
- HoCa (NCT07406412)
- Testing
- Surgical removal of ovaries, Hormone Replacement Therapy (HRT)
- Where
- 7 sites in Finland
- Volunteers
- 120 people
- Sponsor
- University of Jyvaskyla
Emotional Eating, Overweight or Obesity
Efficacy of Satisens® in Reducing Emotional Eating
This study evaluates the efficacy of Satisens®, a dietary supplement composed of plant extracts, in reducing emotional eating and sweet cravings in healthy adults.
- Conditions
- Emotional Eating, Overweight or Obesity, Hormonal Changes, Neurotransmitter Agents
- Trial name
- Satisens (NCT07079046)
- Testing
- Intervention 1: Satisens®
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- José Enrique de la Rubia Ortí, Ph
Contraceptive Usage, Metabolic Syndrome
Metabolic Profile of Users of Hormonal and Non-hormonal Contraceptives
Evaluation of metabolic profile of users of hormonal and non-hormonal contraceptives during five years follow-up
- Conditions
- Contraceptive Usage, Metabolic Syndrome, Body Weight Changes
- Trial name
- NCT03383185
- Testing
- Intrauterine device, Combined Oral Contraceptive, Progestin-only pills
- Where
- Brazil
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Bariatric Surgery, Obesity
Endocrinological and Neuronal Aspects of Bariatric Surgery
The overall aim of the proposed project is to investigate the contribution of changes in neuronal food processing, hypothalamic reactivity and hormonal factors to weight loss after bariatric surgery.
- Trial name
- BACEN (NCT04634929)
- Testing
- bariatric surgery, conservative diet
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Heidelberg Medical Center
Overtraining Syndrome
Changes in the Hormonal and Inflammatory Profile of Young Sprint- and Endurance-trained Athletes.
One essential element of athlete training is conditioning camps, where athletes undergo a rigorous and targeted training schedule to prepare for upcoming sporting events.
- Trial name
- CHIPYA (NCT06150105)
- Testing
- Exercise training
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Hot Flashes, Night Sweats
Comparison of Hormonal Therapy: Mediating Hot Flashes Tapering Regimens for Mediating Hot Flashes
This study will evaluate whether there is a difference in the proportion of women who report a worsening severity of their hot flashes between three tapering schedules for one accepted HT/ET regimen.
- Trial name
- NCT00547001
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Healthy
ORAL T-8 Oral Testosterone for Male Hormonal Contraception
The purpose of this study is to test how the body absorbs a new form of oral testosterone (T). On Day 1 and Day 9 there are overnight stays in the General Clinical Research Center at the University of Washington to monitor blood…
- Trial name
- Oral T8 (NCT01167829)
- Testing
- Oral Testosterone, Acyline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Washington
Smoking
Brief Interventions on Smoking for Hormonal Contraceptive Users
Despite rising smoker rates, particularly in girls and young women, only few studies have focused on smoking cessation in young smokers.
- Trial name
- BRISC (NCT00726141)
- Testing
- Brief intervention, Motivational Interviewing, Expert System
- Where
- Germany
- Volunteers
- 699 people
- Sponsor
- University of Luebeck