Clinical trials: Hormonal Contraception
Contraception
Pharmacists Expand Access to Reproductive heaLthcare
Prospective cohort study of women presenting to initiate hormonal contraception, prescribed by a clinician or pharmacist. Women will be followed for one year to assess contraceptive continuation and unintended pregnancy rates, as…
- Trial name
- PEARL (NCT03830567)
- Testing
- Pharmacist prescription, Clinician prescription
- Where
- United States
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
HIV Infections
Hormonal Birth Control and the Risk of Acquiring HIV
The purpose of this study is to find out whether hormonal birth control increases, decreases, or does not change the risk of women becoming infected with HIV.
- Trial name
- NCT00006324
- Testing
- Ethinyl estradiol/levonorgestrel, Medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 6,360 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cystitis, Interstitial, Dysmenorrhea
Chronic Pain Risk Associated With Menstrual Period Pain
The purpose of this study is to determine if some women with dysmenorrhea (painful periods) are at higher future risk of developing chronic pelvic pain (CPP) and if oral contraceptives (OC) can be used to reverse this chronic…
- Conditions
- Cystitis, Interstitial, Dysmenorrhea, Migraine Disorders, Pelvic Pain
- Trial name
- CRAMPP (NCT02214550)
- Testing
- cyclic microgestin 1/20, continuous microgestin 1/20
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Contraception
Effects of Hormonal Contraceptives on Liver Proteins and Coagulation Factors: A Comparison of a Contraceptive Vaginal Ring and an Oral Contraceptive
The purpose of this 3-month (cycle) study was to evaluate the effects of hormonal contraceptives containing a progestin and an estrogen on liver proteins and coagulation factors that are sensitive to estrogen.
- Trial name
- NCT00213096
- Testing
- Nestorone/ethinyl estradiol contraceptive vaginal ring; levonorgestrel/ethinyl estradiol oral contraceptive
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Population Council
Musculoskeletal Injury, Hypogonadism
Adaptions and Resiliency to Multi-Stressor OpeRations
Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits.
- Conditions
- Musculoskeletal Injury, Hypogonadism, Hormonal Contraception
- Trial name
- ARMOR (NCT06455969)
- Testing
- Goserelin 3.6 MG, Multi-Stressor Training, Testosterone gel (AndroGel 5g)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bradley Nindl
Uterine Hemorrhage, Contraception
Does Concomitant Use of Combined Oral Hormonal Steroids Stop Bleeding in Women Using Etonogestrel Implants (Implanon/Nexplanon®)?: A Randomized Controlled Study
The specific aims are to determine if more women using Etonogestrel (ENG) contraceptive implants who report a bleeding-spotting episode of at least seven days will stop bleeding within 3 days of beginning a 14-day course of…
- Trial name
- NCT01968135
- Testing
- Combined Oral Contraceptive Pill
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pharmacokinetics
The Pharmacokinetics of 12 Week Continuous Patch Use
Investigators propose a descriptive pharmacokinetic study of the serum hormone levels of estrogen and progesterone with extended use (12 weeks) of the contraceptive patch.
- Trial name
- NCT02585999
- Testing
- Xulane Contraceptive Patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Contraception
Male Hormonal Contraceptive Development-ACY-5
The purpose of this research study is to help in the development of male contraception (birth control).
- Trial name
- ACY-5 (NCT00161447)
- Testing
- Acyline, Testosterone Gel, Depo-Medroxyprogesterone
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Washington
Contraceptive Usage, Vaginal Epithelial Disruption
Hormonal Contraception and Vaginal Health
The purpose of this study is to help determine if the route by which women receive hormonal contraception causes different changes to occur in the lining of the vagina.
- Trial name
- NCT00612508
- Testing
- Desogen (ethinyl estradiol and desogestrel), NuvaRing (ethinyl estradiol and etonogestrel)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
The Direct Access Study: Access to Hormonal Birth Control Through Community Pharmacies
Hormonal birth control methods include birth control pills, patches, and vaginal rings; they are normally available only with a doctor's prescription.
- Trial name
- NCT00065871
- Testing
- Contraceptive Screening by Pharmacist, Contraceptive Prescribing by Pharmacist
- Where
- 5 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Contraception
Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 Cycles
To demonstrate the contraceptive efficacy of LF111 . To demonstrate the safety and tolerability of LF111 and assessment of pharmacokinetics of LF111.
- Trial name
- NCT02269241
- Testing
- LF111 (drospirenone)
- Where
- 37 sites in United States
- Volunteers
- 1,552 people, healthy volunteers welcome
- Sponsor
- Laboratories Leon Farma, S.A.
Contraception
A Multicentre, Prospective, Open-label, Non-comparative Study
As there are no recent studies conducted in Italy on the profile of this COC, the purpose of this study is to evaluate its efficacy and tolerability in a given subset of women residing in Italy that are in need of contraception.
- Trial name
- NCT06067256
- Testing
- Female Contraceptive
- Where
- Italy
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Italfarmaco
Lactation
Combined Hormonal Versus Progestin Only Contraception During Lactation
Objective: To determine and compare the effect of low dose estrogen combined hormonal contraceptives and progestin-only contraceptives on lactation.
- Trial name
- NCT00374972
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Cerebral Perfusion, Contraception
The Effects of the Female Hormones on Cerebral Perfusion
Measuring brain perfusion is biased by a inter- and intrasubject variability, caused by physiological and lifestyle factors. In this study, the investigators want to investigate the variations in cerebral perfusion and other…
- Conditions
- Cerebral Perfusion, Contraception, Menstrual Cycle
- Trial name
- NCT03299179
- Testing
- MRI scan, Physiological monitoring, Blood sample
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Ghent
Substrate Utilization
Substrate Utilization and Hormonal Status in Women
Women sexual hormones (i.e. estrogen) are involved in the regulation of substrate utilization and storage. Being under oral contraception (OC) may conduct to metabolic and hormonal modifications, but results are confused…
- Trial name
- NCT01095614
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand