Clinical trials: Hormone Deficiency
Ovarian Diseases, Ankylosing Spondylitis
Ovarian Reserve and Ankylosing Spondylitis
The aim of this study was to determine the status of ovarian reserve in patients with ankylosing spondylitis (AS) using anti-mullerian hormone (AMH) level and antral follicle count (AFC).
- Conditions
- Ovarian Diseases, Ankylosing Spondylitis, Anti-Mullerian Hormone Deficiency
- Trial name
- NCT04209881
- Testing
- ovarian reserve for Ankylosing spondylitis and control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Vitamin D Deficiency
Reference Interval of Vitamin D of Coastal Fishermen in Cox's Bazar District of Bangladesh
Lack of adequate sun exposure due to urbanization is prone to hypovitaminosis D. Vitamin D (25-hydroxyvitamin D) deficiency is now a major health concern in the western world.
- Trial name
- NCT04986319
- Testing
- Serum vitamin D assay
- Where
- 2 sites in Bangladesh
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders
Growth Hormone Deficiency With Pituitary Anomalies
Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency
The Macimorelin Growth Hormone Stimulation Test (GHST) will be compared with the Insulin Tolerance Test (ITT) in an open-label, randomized, 2-way crossover Trial.
- Trial name
- NCT02558829
- Testing
- Macimorelin, Insulin
- Where
- 27 sites in United States, Austria and 7 more
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- AEterna Zentaris
Early Childhood Caries, Vitamin D Deficiency
Vitamin D Status With Early Childhood Caries
Studies that give people vitamin D supplements to prevent caries have found that vitamin D is effective at preventing the development of caries.
- Trial name
- NCT03521492
- Testing
- serum vitamin D , calcium , parathyroid hormone and albumin level
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Acromegaly, Growth Hormone Deficiency
Inter-Assay Growth Hormone and IGF-I Variability
The purpose of this study is to demonstrate the degree of variability in commercially available assays for Growth Hormone measurement in the context of clinical decision making for Growth Hormone (GH) deficiency and Acromegaly…
- Trial name
- NCT00638287
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Pediatric Growth Hormone Deficiency (PGHD)
A Bioequivalence Study of Two Different Processes of PEG-rhGH Preparations
The purpose of this study is to investigate whether PEG-rhGH with new preparation is bioequivalent to PEG-rhGH with present preparation.
- Trial name
- NCT06840691
- Testing
- PEG-rhGH with new preparation (T), PEG-rhGH with present preparation (T)
- Where
- China
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Calcium Deficiency, Vitamin D Deficiency
Human Pharmacology Trial of Calcium-vitamin D3 Tablet in Healthy Participants
The purpose of this study is to demonstrate that the intestinal absorption of calcium from a newly developed calcium carbonate-vitamin D3 chewable tablet formulation increases the amount of calcium excreted in urine and decreases…
- Trial name
- Osteopro (NCT01639222)
- Testing
- Calcium 500 mg and Vitamin D3 800 IU, Low calcium meals
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Takeda
Crohn Disease, Ovary Disease
Ovarian Reserve in Crohn's Disease
Crohn's disease reduces fertility by inducing inflammation both directly and in the fallopian tubes and ovaries and indirectly through surgical interventions and tubal adhesions associated with disease treatment.
- Conditions
- Crohn Disease, Ovary Disease, Anti-Mullerian Hormone Deficiency
- Trial name
- NCT03897400
- Testing
- AMH levels in young women with crohn's disease will be considered.
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Growth Hormone Deficiency, Traumatic Brain Injury
Charactertizing Growth Hormone Deficiency in Traumatic Brain Injury
The goal of this observational study is to characterize the impact of growth hormone deficiency (GHD) on quality of life, symptom burden, and sleep in adults with traumatic brain injury (TBI), and to evaluate whether these…
- Trial name
- NCT07795736
- Testing
- Not applicable (observational study)
- Where
- 2 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Vitamin D Deficiency, Secondary Hyperparathyroidism
Vitamin D Status in Males in Jerusalem Area and Its Correlation to Parathyroid Hormone (PTH) Level and Bone Mineral Density
Because of its high sun exposure, Israel was traditionally supposed to be protected from vitamin D deficiency, and the country food products hardly contain vitamin D supplements.
- Conditions
- Vitamin D Deficiency, Secondary Hyperparathyroidism, Osteomalacia
- Trial name
- NCT01025128
- Testing
- 25 OH vitamin D
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Hypopituitarism, Central Diabetes Insipidus
Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)
Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function.
- Conditions
- Hypopituitarism, Central Diabetes Insipidus, Panhypopituitarism, Psychological Disorder
- Trial name
- NCT04902235
- Testing
- Experimental: CRH administration
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cognitive Impairment, Estrogen Deficiency
Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function
Complaints about memory and thinking are common in women as they go through menopause. The female hormone estrogen is important for both the health of both the brain and the blood vessels.
- Conditions
- Cognitive Impairment, Estrogen Deficiency, Menopause, Endothelial Dysfunction
- Trial name
- NCT03112226
- Testing
- GnRHant + E2
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Severe Adult Growth Hormone Deficiency
Effect of Pegvisomant on GH/IGF-I Relationship in GHD
Approximately 50% of middle-aged patients with severe AGHD have a normal age-related serum IGF-I. It remains unclear if in these individuals serum IGF-I is GH dependent or independent.
- Trial name
- NCT00468624
- Testing
- arginine stimulation test after each limb
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Christie NHS Foundation Trust
Diagnosis of Adult Growth Hormone Deficiency (AGDH)
Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test.
The diagnosis of growth hormone deficiency (GHD) in adults is established by laboratory testing in patients with an appropriate clinical history of hypothalamic pituitary disease.
- Trial name
- NCT00448747
- Testing
- AEZS-130 (formerly ARD-07), L-ARG+GHRH
- Where
- 13 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- AEterna Zentaris