Clinical trials: Hormone Replacement
Covid-19, SARS
Tocilizumab vs CRRT in Management of Cytokine Release Syndrome (CRS) in COVID-19
Some patients infected with the COVID-19 can develop uncontrolled immune response, leading to potentially life-threatening damage to lung tissue. Tocilizumab was first approved by the U.S.
- Conditions
- Covid-19, SARS, Cytokine Storm, Cytokine Release Syndrome
- Trial name
- TACOS (NCT04306705)
- Testing
- Tocilizumab, Standard of care, Continuous renal replacement therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
Neoadjuvant Therapy, Chemotherapy
The Use of Molecular Breast Imaging in the Evaluation of Tumor Response to Neoadjuvant Therapy in Women With Breast Cancer
In patients with breast cancer who undergo neoadjuvant chemotherapy or neoadjuvant hormone therapy molecular breast imaging (MBI) is an accurate test for assessing response rate to neoadjuvant therapy.
- Conditions
- Neoadjuvant Therapy, Chemotherapy, Hormone Replacement Therapy, Breast Cancer
- Trial name
- NCT01023802
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Postmenopausal
Effect of 17ß-estradiol on Inflammatory-immune Responses in Post-menopausal Women According to Administration Route
The aim of this pilot study conducted in post-menopausal women is to evaluate the effect of 17ß-estradiol administration on inflammatory-immune cells, namely antigen-presenting cells (monocytes/dendritic cells), and more…
- Trial name
- NCT00701337
- Testing
- oestradiol
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Critical Illness, Acute Kidney Injury
Continuous Renal Replacement Therapy Circuit Lifespan in Intensive Care Patients
The goal of this retrospective observational study is to evaluate how long continuous renal replacement therapy (CRRT) circuits remain in use in adult intensive care unit patients and to describe how CRRT pressure measurements…
- Trial name
- NCT07842562
- Testing
- Archived CRRT Device Log Data
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Qualitative, Nicotine Replacement Therapy
Experiences of Pregnant Women Who Use NRT in Pregnancy as Part of a Quit Attempt
This study is largely a qualitative study with a small survey component. The aim of the survey would be to gain a quantitative perspective of how women use NRT after this has been prescribed by stop smoking services (SSS).
- Conditions
- Qualitative, Nicotine Replacement Therapy, Pregnancy
- Trial name
- NCT02125370
- Testing
- Qualitative and survey
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Non-thyroidal Illness Syndrome
Peri-operative Oral Triiodothyronine Replacement Therapy to Decrease the Risk of Transient Atrial Fibrillation After Off-pump Coronary Artery Bypass Surgery
This study is planned to medicate oral T3(Liothyronine)to the patients who are planned to have OPCAB(off- pump coronary bypass graft surgery.
- Trial name
- NCT01153360
- Testing
- liothyronine sodium
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Diabetes Mellitus, Type 2
Effect of Meal Replacement Therapy on Glucose Control and Metabolic Parameters in Patients With Uncontrolled Diabetes
To evaluate the effect of meal replacement therapy on glucose control and other metabolic parameters in patients with uncontrolled type 2 diabetes. Methodology: This is an open-label, prospective, randomized control trial study.
- Trial name
- NCT06862180
- Testing
- Meal replacement therapy
- Where
- Malaysia
- Volunteers
- 108 people
- Sponsor
- Hospital Universiti Sains Malaysia
Pregnancy, Smoking Behavior
HISTOLOGICAL RESULTS IN TRANSGENDER INDIVIDUALS ASSIGNED TO FEMALES AT BIRTH UNDERGOING GENDER AFFIRMATION SURGERY AND IN TESTOSTERONE THERAPY
The aim of this study is to report histological results of genital organs removed during gender affirmg surgery in transgender people assigned female at birth (AFAB), to increase the knowledge about the long-term effects of…
- Conditions
- Pregnancy, Smoking Behavior, Testosterone Replacement Therapy, Drugs
- Trial name
- NCT06710496
- Testing
- analysis of medical records
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Veterans, Tobacco Use Disorder
Varenicline for Smoking Reduction in Veterans Not Ready To Quit
In order to reduce the prevalence of cigarette smoking among Veterans, it is vital that healthcare providers offer effective tobacco treatment to all Veterans who smoke, including those not ready to make a quit attempt.
- Conditions
- Veterans, Tobacco Use Disorder, Cigarette Smoking, Tobacco Dependence
- Trial name
- NCT06966362
- Testing
- Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT)
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- VA Office of Research and Development
Cushing's Syndrome, Postoperative
Contralateral Adrenal Volume Predicts Duration of Postoperative Steroid Replacement Therapy in Non-ACTH-dependent Hypercortisolism
To identify preoperative factors influencing the duration of steroid replacement therapy after adrenalectomy/adrenal-sparing surgery in patients with non-ACTH-dependent hypercortisolism.
- Conditions
- Cushing's Syndrome, Postoperative, Glucocorticoid, Prediction
- Trial name
- NCT07282223
- Testing
- observational diagnostic model development
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Peking University First Hospital
Thyroid Carcinoma, Hypothyroidism
The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma
The purpose of this study is to evaluate whether taking thyroid hormone medication with beverages other than water, decreases absorption of the medication by the intestine.
- Trial name
- NCT01707056
- Testing
- Black Coffee, Coffee with Milk, Black Tea
- Where
- 3 sites in United States
- Sponsor
- Medstar Health Research Institute
Type 2 Gaucher Disease
Convection-Enhanced Delivery of Glucocerebrosidase to Treat Type 2 Gaucher Disease
This study will use an experimental method of delivering the enzyme glucocerebrosidase directly into the brain of a patient with Gaucher disease to treat disease symptoms.
- Trial name
- NCT00244582
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
COVID-19
Intravenous Immunoglobulin Replacement Therapy for Persistent COVID-19 in Patients With B-cell Impairment
This is a multicenter, randomized controlled trial aiming to investigate the efficacy of intravenous immunoglobulin (IVIG) replacement therapy under the hypothesis that immunoglobulin replacement would have therapeutic effects on…
- Trial name
- NCT06159283
- Testing
- Immunoglobulins
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Jaehoon Ko
Acute Kidney Injury, COVID-19
Incidence of Acute Kidney Injury in Covid-19
Acute kidney injury (AKI) in Covid-19 patients is a topic that receives little attention in the literature, although being important in clinical practice in the ICU, particularly in Oman.
- Conditions
- Acute Kidney Injury, COVID-19, Critically Ill
- Trial name
- COVIDAKI (NCT05467956)
- Testing
- Covid-19
- Where
- Oman
- Volunteers
- 286 people
- Sponsor
- Sultan Qaboos University
Acute Kidney Injury
Renal Replacement Therapy and In-Hospital Mortality Incidence in Cardiac Surgery Associated Acute Kidney Injury
The goal of this study is to analyse the relation of severe acute kidney injury post cardiac surgery which characterised by the need of renal replacement therapy, with in-hospital postoperative mortality incidence.
- Trial name
- NCT06091982
- Testing
- Renal Replacement Therapy (RRT)
- Where
- Indonesia
- Volunteers
- 1,113 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Thyroid Diseases, Respiratory Failure
Respiratory Muscle Function After Thyroid Hormone Replacement Therapy in Nonthyroidal Illness Syndrome
Although it is now recognized that a variety of respiratory abnormalities, such as diaphragmatic dysfunction, can be present in primary hypothyroidism and reverse with adequate hormone treatment, the role of thyroid hormone…
- Trial name
- NCT03157466
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Smoking Cessation, Tobacco Use Cessation
Interactive Communication Technologies and Nicotine Replacement Therapy Sampling for Smokers
Brief advice combined with active referral to smoking cessation (SC) services increases quitting. We aim to strengthen the effect of combined intervention by using interactive communication technologies and nicotine replacement…
- Trial name
- NCT04001972
- Testing
- Brief advice (AWARD model), NRT-S, IM Apps and Chatbot
- Where
- Hong Kong
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sepsis
Normal Saline Versus Ringer's Lactate for Initial Fluid Resuscitation in Sepsis
This clinical trial aims to determine if the type of intravenous fluid used for initial resuscitation affects the short-term outcomes of adult patients with sepsis who are treated in the emergency department.
- Trial name
- NCT07240701
- Testing
- Ringer's Lactate, Normal Saline (0.9% Sodium Chloride)
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Egemen Yildiz
Acute Pancreatitis
Early High-volume Continuous Veno-venous Hemofiltration for Patients With Severe Acute Pancreatitis
The purpose of this study is to determine the effect and safety of early high-volume continuous veno-venous hemofiltration for patients with severe acute pancreatitis.
- Trial name
- EHVCVVHSAP (NCT01595672)
- Testing
- AN69 hemofilter, conventional treatments
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Air Force Military Medical University, China
Infection During Renal Replacement Therapy, Critically Ill
Ceftaroline Pharmacokinetics in Continuous Renal Replacement Therapy
Dosing of ceftaroline in patients with chronic kidney disease is defined, but there is no data on pharmacokinetics and pharmacodynamics of the drug in patients receiving continuous renal replacement therapy (CRRT).
- Trial name
- NCT04152694
- Testing
- Ceftaroline levels in CRRT
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore
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