Clinical trials: Hormones
HIV, Prophylaxis
Cabotegravir-Hormone PK/PD Interactions for HIV Prevention
This is a research study to better understand how long-acting cabotegravir (CAB-LA) works to prevent HIV in people. This study will also evaluate the impact of endogenous and therapeutic hormones on CAB-LA pharmacology.
- Conditions
- HIV, Prophylaxis, Injectable
- Trial name
- CHIPP-PrEP (NCT07672717)
- Testing
- Cabotegravir Injectable Suspension (CAB LA)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Polycystic Ovary Syndrome
AMH, Glucose Intolerance and Metabolic Syndrome in PCOS
Association between serum anti-Mullerian hormone (AMH) level and prevalence of glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS)
- Trial name
- NCT02676518
- Testing
- serum
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Healthy
Anti-mullerian Hormone Levels in Healthy Females
The purpose of this study is to have a better understanding of the normal blood levels of AMH in females from 0-18 years of age and how the blood AMH levels correspond to a female's reproductive development.
- Trial name
- AMH (NCT04537390)
- Testing
- Blood sample collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erin Rowell
Transgender Women, HIV/AIDS
Effects of Gender-Affirming Hormone Therapy Among Transgender Women
In this study, investigators plan to evaluate the cardiometabolic effects of initiating gender-affirming hormone therapy among transgender women with and without HIV.
- Conditions
- Transgender Women, HIV/AIDS, Cardiovascular Diseases, Metabolic Disease
- Trial name
- NCT04128488
- Testing
- Abdominal MR Imaging, Cardiac MRI/MRS, Oral Glucose Tolerance Testing
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypopituitarism, Central Diabetes Insipidus
Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)
Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function.
- Conditions
- Hypopituitarism, Central Diabetes Insipidus, Panhypopituitarism, Psychological Disorder
- Trial name
- NCT04902235
- Testing
- Experimental: CRH administration
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Obesity, Dietary Intervention
Effects of Boron and Mediterranean Diets on Gut Microbiota and Metabolic Health
This study investigated the effects of a boron-rich diet compared with a Mediterranean-style diet (Smart Alternative Food Formulation; SAFF) on obesity-related outcomes in adults.
- Conditions
- Obesity, Dietary Intervention, Gut Microbiota, Cardiometabolic Risk Factors
- Trial name
- BOR-SAFF (NCT07156097)
- Testing
- Mediterranean-style Diet (SAFF), Boron-rich Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dicle University
Dietary Behavior, Stress
Dietary Plant Hormone and Mental Health
The aim of this cross-sectional online study is to investigate the association between regular feeding behavior and stress, sleep as well as anxiety and depressive symptoms in healthy subjects.
- Conditions
- Dietary Behavior, Stress, Sleep, Depression, Anxiety
- Trial name
- NCT05276479
- Testing
- Anonymous online survey on dietary habits and mental health
- Where
- Switzerland
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Bern
Overweight and Obese Women
Impact of Beta-glucan Supplementation During Calorie and Carbohydrate-restricted Diet on Body Weight and Body Fat Loss, Appetite, and Gastrointestinal Appetite Hormones.
This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite…
- Trial name
- NCT07299942
- Testing
- Beta-glucan addition to a restricted calorie of meal replacements and carbohydrate diet.
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Risk Factor, Cardiovascular, Physical Activity
Exercise Effects on Appetite-regulating Hormones and Cardiovascular Risk Factors
The aim of this study is to examine the effect of a single bout of moderate exercise, standardized breakfast and buffet meal on appetite-related hormones, type two diabetes and cardiovascular risk factors with a comparison…
- Conditions
- Risk Factor, Cardiovascular, Physical Activity, Pre-diabetes
- Trial name
- NCT03698786
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kingston University
Post Partum Depression
Relationship-Based Intervention for Post-Partum Depression
A short term dyadic psychotherapy intervention for mothers with Post-Partum depression and their babies in the first year of life was developed.
- Trial name
- NCT04193462
- Testing
- Post-partum depression- Dyadic psychotherapy-, Post-partum depression- Psycho-educational therapy
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Interdisciplinary Center Herzliya
Osteoporosis
Long-term Nutritional Intervention Study to Determine How Protein Affects Calcium Metabolism
Osteoporosis is a major health problem in men and women in this country and the incidence of this disease is rising. We think that environmental factors such as nutrition may play a role in the increasing prevalence of…
- Trial name
- NCT00671944
- Testing
- Low protein diet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Yale University
Roux-en-Y Gastric Bypass, Obesity
Meal Glycaemic Index and Exercise After Gastric Bypass
The study will evaluate postprandial glucose excursions and gut hormone secretion after ingestion of meals with different glycaemic index (GI) values (high vs low) followed by an acute bout of exercise or rest in gastric bypass…
- Trial name
- NCT03478098
- Testing
- Low GI mealtest, Low GI mealtest and subsequent exercise, High GI mealtest
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kirstine Nyvold Bojsen-Moeller
Healthy Volunteers
Effect of Short Term Growth Hormone Releasing Hormone in Healthy Men
The purpose of this trial is to examine the short-term effects of Growth Hormone Releasing Hormone (GHRH, tesamorelin) administration in healthy men.
- Trial name
- NCT00850564
- Testing
- Growth Hormone Releasing Hormone (Tesamorelin)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity, Women
Probiotics' Effects on Hormones, Body and Mood in Obese Women
To evaluate the regulatory effect of probiotics formula on visceral fat metabolism and sex hormone balance in obese women.
- Trial name
- NCT07013409
- Testing
- Probiotic, Maltodextrin
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Growth Hormone, Elderly
The Effect of Local Injectet GH on the Collagen Synthesis in the Ligamentum Patella
Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached.
- Trial name
- NCT01158612
- Testing
- Growth Hormone
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy, Appetite
Pasta Formulations, Portion Sizes and Their Effect on Appetite
Investigators are interested in learning how appetite responds to pasta containing different amounts of protein and fiber when provided in two different portion sizes.
- Trial name
- SET (NCT01199770)
- Testing
- Control, small, Experimental B, small, Experimental pasta C, small
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Healthy Volunteers
Gut Hormone Secretion and Macronutrients
The role of gut hormone (GLP-1, GIP, PYY...) in glucose homeostasis has been widely demonstrated. Furthermore modifications in their pattern of secretion seem to be involved in the improvement of glucose control in obese patients…
- Trial name
- NCT00869453
- Testing
- test meal, glucose, fat
- Where
- 2 sites in Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Endocrine System Diseases
Effect of a Test Meal on Satiation Hormones in Obese and Normal Weight Adolescents
The objective of this study is to examine ghrelin, amylin, glucagon and glucagon-like peptide (GLP)-1 responses to a test meal in lean and obese individuals.
- Trial name
- NCT02020395
- Testing
- test meal (500 kcal)
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Other Complications Associated With Artificial Fertilization
Efficacy of Luteinizing Hormone (LH) Activity in Low Responder Patients With Transdermal Testosterone
The investigators have previously demonstrated the utility of transdermal testosterone in in vitro fertilization (IVF) low responder patients.
- Trial name
- NCT01291212
- Testing
- Testosterone and FSHr-LHr, testosterone and FSHr alone
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Healthy
Effect of Antidepressants on Sex Hormone Levels and Sexual Functioning
This study will evaluate the effect of antidepressants on sex hormone levels in women and if the potential changes in sex hormone levels are related to sexual side effects.
- Trial name
- NCT00611975
- Testing
- Fluoxetine, Bupropion
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
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